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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Acute Myeloid Leukemia: Updates on Diagnosis, Treatment and Management

edited by

Francesco Lanza

and

Giovanni Marconi

submission deadline 31 Oct 2026 | 2 articles | Viewed by 6492 | Submission Open

Keywords: acute myeloid leukemia; treatment; targeted therapy; molecular profiling; resistance

(This special issue belongs to the Section Methods and Technologies Development)

From Molecular Insights to Cancer Treatments: Progress in Translational Science

edited by

Sanjay V. Malhotra

, Dhanir Tailor and

Annah Rolig

submission deadline 31 Oct 2026 | 3 articles | Viewed by 6091 | Submission Open

Keywords: cancer biology; therapeutics; molecular targets; translational research

(This special issue belongs to the Section Cancer Therapy)

Significance of CAR T-Cell Therapy in Aggressive B-Cell Lymphoma Treatment

edited by

Wing Keung Chan

submission deadline 31 Oct 2026 | 3 articles | Viewed by 5645 | Submission Open

Keywords: CAR-T therapy; non-hodgkin lymphoma; hodgkin lymphoma; CAR-T persistence; immune-related adverse events (irAEs); resistance mechanisms; combination therapy; tumor microenvironment; multiomics data analysis

(This special issue belongs to the Section Cancer Therapy)

Oral Cancer and Precancerous Lesions: Advances in Diagnosis, Prognosis, and Therapy

edited by

Maria Maddalena Marrapodi

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5034 | Submission Open

Keywords: potentially malignant oral disorders (PMODs); malignant transformation; oral cancer and precancerous lesions

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Artificial Intelligence in Urological Oncology: Applications in Imaging, Prognostics, and Precision Disease Management

edited by

Sabine D. Brookman-May

submission deadline 31 Oct 2026 | 4 articles | Viewed by 4731 | Submission Open

Keywords: artificial intelligence; machine learning; urological oncology; imaging, precision medicine; digital pathology; therapeutic decision-making

(This special issue belongs to the Section Cancer Therapy)

Stem Cell Origin of Cancers: Biological and Clinical Implications of a Unified Theory of Cancer (2nd Edition)

edited by Shi-Ming Tu, Louis L. Pisters and

John F. Ward

submission deadline 31 Oct 2026 | 2 articles | Viewed by 4435 | Submission Open

Keywords: cancer stem cells; cancer-initiating cell; progenitor cell; epithelial; Mesenchymal transition; pluripotency; plasticity; heterogeneity; embryogenesis; stem-like; stemness

(This special issue belongs to the Section Cancer Pathophysiology)

Current Research in Pediatric Hematological Oncology

edited by

Santhosh Kumar Pasupuleti

and

Tzu-Chieh Ho

submission deadline 31 Oct 2026 | 4 articles | Viewed by 4292 | Submission Open

Keywords: pediatric hematology; childhood leukemia; acute myeloid leukemia (AML); juvenile myelomonocytic leukemia (JMML); acute lymphoblastic leukemia (ALL); immunotherapy; CAR-T cell therapy; targeted therapies; translational research; survivorship; pediatric oncology models

(This special issue belongs to the Section Pediatric Oncology)

Combination Therapy for the Treatment of Breast Cancer

edited by

Xin Wang

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4024 | Submission Open

Keywords: breast cancer; combination therapy; targeted therapy; immunotherapy; endocrine therapy; chemotherapy; anti-body–drug conjugates; treatment resistance; biomarkers

(This special issue belongs to the Section Cancer Therapy)

Molecular Targets and Therapeutic Pathways in Cancer

edited by Ashish H. Shah and Deepa Seetharam

submission deadline 31 Oct 2026 | 3 articles | Viewed by 3632 | Submission Open

Keywords: cancer therapeutics; molecular targets; signal transduction pathways; targeted therapy; drug resistance; precision oncology; tumor microenvironment; immunotherapy; kinase inhibitors; translational cancer research

(This special issue belongs to the Section Cancer Drug Development)

Advanced Strategies in the Care of Hepatocellular Carcinoma Patients (2nd Edition)

edited by

Matteo Donadon

and

Guido Torzilli

submission deadline 31 Oct 2026 | 3 articles | Viewed by 3288 | Submission Open

Keywords: hepatocellular carcinoma; hepatic resection; hepatectomy; liver resection; liver surgery; parenchymal-sparing liver surgery; intraoperative ultrasound; liver-specific magnetic resonance imaging; trans-arterial therapy; liver function; FibroScan

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Synergistic Radiotherapy and Immunotherapy in Cancer Treatment

edited by

Xiaju Cheng

submission deadline 31 Oct 2026 | 4 articles | Viewed by 3268 | Submission Open

Keywords: radiotherapy; immunotherapy; combination therapy; nanomedicine; immunogenic cell death; tumor microenvironment; immune checkpoint inhibitors; abscopal effect; systemic immunity; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Targeted Therapies for Pediatric Nervous System Tumors

edited by

Mohamed S. Abdelbaki

and Nicole Brossier

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3207 | Submission Open

Keywords: glioma; ependymoma; medulloblastoma; pediatric brain tumors; targeted therapy; MEK inhibitors; NTRK inhibitors; glioma neuroscience; diffuse intrinsic pontine glioma

(This special issue belongs to the Section Pediatric Oncology)

Genetic, Epigenetic and Protein Biomarkers in Gynaecological and Breast Cancers

edited by

Apriliana Kartikasari

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3151 | Submission Open

Keywords: gynecological cancers; breast cancer; cancer biomarkers; genetic biomarkers; epigenetic biomarkers; protein biomarkers; microRNA (miRNA); cancer screening; early diagnosis; prognosis; disease monitoring; treatment stratification; therapeutic response; biomarker discovery; biomarker detection methods; translational research

(This special issue belongs to the Section Cancer Biomarkers)

Cancer Cell Motility (2nd Edition)

edited by

Gianluca Aguiari

and

Nicoletta Bianchi

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3140 | Submission Open

Keywords: cancer; EMT; invasion; metastasis; p53-related signaling; apoptosis; autophagy; cell cycle; anticancer drugs

(This special issue belongs to the Section Tumor Microenvironment)

Ras Signaling and Inhibitors: Strategies to Escape Resistance

edited by Gary Piazza

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2546 | Submission Open

Keywords: RAS; MAPK/AKT signaling; resistance; inhibitors; cancer

Risk Factors of Kidney Cancer

edited by

Ken Batai

and

Salvatore La Rosa

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2508 | Submission Open

Keywords: prevention; survivorship; renal cell carcinoma; kidney cancer epidemiology

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

EGFR-Tyrosine Kinase Inhibitor (EGFR-TKI) for Non-Small Cell Lung Cancer

edited by

Francesca Iommelli

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2486 | Submission Open

Keywords: EGFR TKIs; secondary mutations; alternative signaling pathway activation cancer progression; lung cancer

(This special issue belongs to the Section Cancer Therapy)

Glioma: From Intracellular Oncogenic Pathways to Targeting Therapeutic Strategies

edited by

Shilpi Singh

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2473 | Submission Open

Keywords: glioma; targeted therapies; resistance mechanisms; oncogenic pathways; therapeutic resistance; combination therapies; tumor heterogeneity

(This special issue belongs to the Section Cancer Therapy)

Improving Outcomes in Resected Colorectal Liver Metastases: Risk-Stratified Chemotherapy and Aggressive Integration of Thermal Ablation

edited by

Toru Beppu

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2407 | Submission Open

Keywords: colorectal liver metastases (CRLM); liver resection; systemic chemotherapy; recurrence-risk stratification; carcinoembryonic antigen (CEA); carbohydrate antigen 19-9 (CA19-9); circulating tumor DNA (ctDNA); RAS mutation; thermal ablation

(This special issue belongs to the Section Cancer Metastasis)

The Biomarkers of Oral Cancer

edited by

Yasumasa Kakei

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2354 | Submission Open

Keywords: oral cancer; oral squamous cell carcinoma; oral melanoma; surgery; combination therapy; radiation therapy; immunotherapy; drug resistance; biomarker; liquid biopsy; prognosis

(This special issue belongs to the Section Cancer Biomarkers)

Evolving Paradigms in Acute Myeloid Leukemia: From Molecular Risk to Targeted Treatment

edited by Talha Badar

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2173 | Submission Open

Keywords: acute myeloid leukemia; targeted therapy; precision medicine; menin inhibitors; venetoclax; measurable residual disease (MRD); risk stratification; allogeneic hematopoietic cell transplantation; molecular profiling; AML consolidation therapy

Research and Treatment of Hepatocellular Carcinoma

edited by Chung Cheung Thomas Yau

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2112 | Submission Open

Keywords: hepatobiliary cancer; biomarker; immunotherapy; targeted therapy; combination treatments

(This special issue belongs to the Section Cancer Therapy)

Overcoming Drug Resistance: Precision Medicine Drug Therapy

edited by

Chenyu Sun

, Yuting Huang and Raveena Manem

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2003 | Submission Open

Keywords: drug resistance; precision medicine; molecular and cellular mechanisms; biomarker-guided therapy; genomic profiling; combination treatment; novel drug delivery system

(This special issue belongs to the Section Cancer Drug Development)

AI-Driven Advanced Radiotherapy: Towards Personalized, Predictive and Adaptive Cancer Treatment

edited by Zhen Tian and Chaoqiong Ma

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1910 | Submission Open

Keywords: radiotherapy; artificial intelligence; machine learning; deep learning; outcome prediction; treatment planning; adaptive RT; personalized RT; radiomics

(This special issue belongs to the Section Methods and Technologies Development)

Metabolism and Precision Oncology

edited by Rays H. Y. Jiang and Gloria C. Ferreira

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1858 | Submission Open

Keywords: cancer metabolism; precision oncology; tumor microenvironment; immunometabolism; metabolic reprogramming; redox biology; metabolomics; lipid metabolism; mitochondrial function; therapeutic targeting

(This special issue belongs to the Section Cancer Pathophysiology)

Pituitary Tumors: Molecular Insights, Diagnosis, and Targeted Therapy—Third Edition

edited by

Kazunori Kageyama

and

Mitsuru Nishiyama

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1629 | Submission Open

Keywords: acromegaly; adrenocorticotropic hormone; Cushing’s disease; diagnosis; growth hormone; pituitary tumor; proliferation; transcriptional factor; treatment

Molecular Markers and Targeted Therapy for Hepatobiliary Tumors: 2nd Edition

edited by Masaki Kuwatani

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1575 | Submission Open

Keywords: cholangiocarcinoma; hepatocellular carcinoma; molecule; gene; chemotherapy; phototherapy

Precision Medicine in Hematological Malignancies: Current Insights and Future Directions

edited by Giuseppe Saglio and Mohamed Yassin

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1554 | Submission Open

Keywords: hematological malignancies; precision medicine; targeted therapy; next-generation sequencing; biomarkers; molecular profiling

(This special issue belongs to the Section Cancer Therapy)

The Role of Lifestyle Choices in Cancer Risk

edited by Itunu O. Sokale, Aaron P. Thrift and

Xiaotao Zhang

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1321 | Submission Open

Keywords: cancer risk; lifestyle; behavioral factors; outcome; cancer prevention

The Next Generation of Prognosis: Novel Biomarkers in AML and MDS

edited by

Marijana Virijevic

, Andrija Bogdanovic and Ljubomir Jakovic

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1303 | Submission Open

Keywords: acute myeloid leukemia; myelodysplastic syndrome; biomarkers; minimal residual disease; novel prognostic factors; immune-related biomarkers; molecular targets; genomics; risk stratification

(This special issue belongs to the Section Clinical Research in Cancer)

Advances in Biliary Tract Cancer: Multidisciplinary Perspectives in Surgery, Endoscopic Management, and Epidemiology

edited by Hiroyuki Kato

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1264 | Submission Open

Keywords: biliary tract cancer; cholangiocarcinoma; gallbladder cancer; ampullary cancer; hepatobiliary surgery; ERCP; biliary drainage; epidemiology; immunotherapy; multidisciplinary treatment; translational research

Advances in Imaging Techniques of Molecular Oncology (2nd Edition)

edited by

Angela Spanu

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1255 | Submission Open

Keywords: cancer; oncological imaging; molecular imaging; SPECT/TC; PET/CT; PET/MRI; DWI; DCE-MRI; nanotheranostics; artificial intelligence; radiomics; theranostics

(This special issue belongs to the Section Methods and Technologies Development)

Prognostic Markers in Endometrial Cancer

edited by

Andrzej Semczuk

and Maciej Jóźwik

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1196 | Submission Open

Keywords: endometrial cancer; prognostic markers; overall survival; disease-free survival; genetic markers; immunohistochemical markers; immunological markers

(This special issue belongs to the Section Cancer Biomarkers)

Non-Melanoma Skin Cancer: Promises and Challenges

edited by

Francesca De Felice

and

Valerio Nardone

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1108 | Submission Open

Keywords: non-melanoma skin cancer; AI; radiotherapy; immunotherapy; surgery; biomarker; technique

(This special issue belongs to the Section Cancer Therapy)

Role of Myeloid Cells in the Regulation of Cancer Onset and Development

edited by Rita Campanelli

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1083 | Submission Open

Keywords: myeloid cells; myeloid-derived suppressor cells; hematological malignancies; solid cancers; inflammation; angiogenesis

(This special issue belongs to the Section Tumor Microenvironment)

Innovations in Surgical and Management Strategies for Complex and Advanced Gastric Cancer

edited by

Tsutomu Namikawa

and

Kazuhiro Hanazaki

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1074 | Submission Open

Keywords: advanced gastric cancer; surgical innovation; multimodal therapy; minimally invasive gastrectomy (robotic/laparoscopic); perioperative management; immunotherapy; precision medicine; peritoneal metastasis

(This special issue belongs to the Section Clinical Research in Cancer)

Mechanisms of Resistance and Response to Immune Checkpoint Inhibitors in Squamous Cell Carcinomas

edited by

Dan Yaniv

and

Aviram Mizrachi

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1059 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy resistance; squamous cell carcinoma; tumor microenvironment; tumor–immune interactions; immune evasion mechanisms; biomarkers of immunotherapy response; tumor–host interactions neuro-immune signaling; tumor metabolism and immunity

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Feature Papers in Section "Tumor Microenvironment" (2nd Edition)

edited by

Sanjay Gupta

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1040 | Submission Open

Keywords: tumor microenvironment; cancer progression; interactions; therapeutic targeting; immune response

(This special issue belongs to the Section Tumor Microenvironment)

Metabolomic Biomarkers for Cancers

edited by

Emirhan Nemutlu

and Burak Derkuş

submission deadline 31 Oct 2026 | 1 articles | Viewed by 938 | Submission Open

Keywords: metabolomics; lipidomics; fluxomics; cancer biomarkers; precision oncology; biofluids; exosomes; organoids; extracellular vesicles; multi-omics integration; personalized medicine

(This special issue belongs to the Section Cancer Biomarkers)

Omics Data for Cancer Therapies: From Molecular Profiling to Clinical Applications

edited by

Luciano Cascione

submission deadline 31 Oct 2026 | 1 articles | Viewed by 910 | Submission Open

Keywords: multi-omics integration; precision oncology; biomarker discovery; computational oncology; translational cancer research

(This special issue belongs to the Section Cancer Informatics and Big Data)

Biomarkers in the Management of Lung Cancer

edited by Ole Hilberg

submission deadline 31 Oct 2026 | 1 articles | Viewed by 871 | Submission Open

Keywords: lung cancer; biomarker; precision medicine

(This special issue belongs to the Section Cancer Biomarkers)

Metabolic Reprogramming in Cancer: Implications for Tumor Progression, Metastasis, Immune Evasion and Therapy Resistance

edited by

Vasudevarao Penugurti

and Bramanandam Manavathi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 811 | Submission Open

Keywords: cancer and mitochondrial metabolism; metabolic reprogramming; glutamine metabolism; tumor microenvironment; metabolic plasticity; oxidative phosphorylation; drug resistance; immune evasion; cancer metastasis; therapeutic metabolic targeting

(This special issue belongs to the Section Molecular Cancer Biology)

Oral Potentially Malignant Disorders and Oral Cavity Cancer: 2nd Edition

edited by

I-Ta Lee

submission deadline 31 Oct 2026 | 1 articles | Viewed by 774 | Submission Open

Keywords: OPMDs; oral cavity cancer; molecular biology; genomics; pathology; early detection; personalized therapy; immunotherapy; targeted treatment; translational medicine

(This special issue belongs to the Section Cancer Therapy)

Novel Diagnostic and Therapeutic Approaches in Hepato-Pancreato-Biliary Cancer

edited by

Timothy M. Pawlik

submission deadline 31 Oct 2026 | 1 articles | Viewed by 764 | Submission Open

Keywords: cholangiocarcinoma; intrahepatic; resection; targeted therapy; chemotherapy; outcomes

(This special issue belongs to the Section Cancer Therapy)

Current Treatment Options for Rectal Cancer

edited by Jesús Pedro Paredes Cotoré

submission deadline 31 Oct 2026 | 1 articles | Viewed by 739 | Submission Open

Keywords: rectal cancer; therapeutic approach; rectal surgery; neoadjuvant treatment; radiotherapy; immunotherapy; chemotherapy; quality of life

(This special issue belongs to the Section Cancer Therapy)

Molecular Imaging in Oncology: Recent Advances (2nd Edition)

edited by

Lioe-Fee de Geus-Oei

submission deadline 31 Oct 2026 | 1 articles | Viewed by 730 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET; oncology; cancer; SPECT; precision medicine; personalized medicine; biomarker; targeted radionuclide therapies; personalized dosimetry

(This special issue belongs to the Section Cancer Therapy)

Advances in Skull Base Tumor Surgery: From Diagnosis to Minimally Invasive Treatment

edited by James P Chandler and

Ahmad Pour Rashidi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 690 | Submission Open

Keywords: skull base tumors; minimally invasive neurosurgery; advanced imaging; molecular diagnostics; cranial base reconstruction; targeted therapies; radiosurgery; precision medicine

(This special issue belongs to the Section Clinical Research in Cancer)

Pathological and Molecular Insights into Urothelial Carcinoma

edited by Gabriela M. Quiroga-Garza,

Maedeh Mohebnasab

and Dimitrios Korentzelos

submission deadline 31 Oct 2026 | 1 articles | Viewed by 674 | Submission Open

Keywords: bladder cancer; urothelial carcinoma; diagnosis; histopathology; molecular; genomics; biomarkers; prognosis; immunotherapy

The Development and Application of Imaging Biomarkers in Cancer: 2nd Edition

edited by

Abhishek Mahajan

submission deadline 31 Oct 2026 | 1 articles | Viewed by 669 | Submission Open

Keywords: imaging biomarkers; oncology; cancer imaging; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Nutritional Strategies Across the Cancer Continuum: Prevention, Therapeutic Intervention, Support, and Survivorship

edited by

Ananya Gupta

submission deadline 31 Oct 2026 | 1 articles | Viewed by 592 | Submission Open

Keywords: cancer prevention; clinical nutrition; malnutrition and cachexia; sarcopenia and nutrition; dietary patterns as cancer therapy; treatment-related sensory changes; cancer survivorship

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Displaying special issue 201-250 on page 5 of 22.

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