Functional and Structural Insights of Non-coding RNA in Cancer

Dear Colleagues,

The majority of the eukaryotic genome is transcribed into non-coding RNAs (ncRNAs) that are not translated into proteins, and include small non-coding RNAs and long non-coding RNAs. Increasing evidence demonstrates that ncRNAs play key roles in different cellular processes in the cell nucleus, the cytosol, and the extracellular space. NcRNAs frequently elicit their functions as components of RNA–protein complexes (ribonucleoproteins, RNPs) that act in response to a broad spectrum of molecular mechanisms. Different ncRNA biotypes have been reported to be dysregulated in various cancer types, thereby opening diagnostic and therapeutic possibilities in cancer involving ncRNAs. This Special Issue aims to publish research articles elucidating functional and structural aspects of the molecular mechanisms involving ncRNAs during the tumorigenesis and metastasis of different cancer types.

Dr. Guillermo Barreto
Dr. Marco Marcia
Dr. Bruno Charpentier
Guest Editors

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