Translational Research on Exosomes in Cancer

Dear Colleagues,

Exosomes are actively secreted from living cells and found in body fluids as membrane-structured nanovesicles which contain bioactive molecules such as proteins, RNAs, and lipids. The content reflects the donor cells with their microenvironment and plays key endocrine and paracrine roles in the cell–cell communication of diverse biological processes important for both benign and cancer cells.

Circulating tumor-associated exosomes are still not completely understood but have potential as non-invasive novel biomarkers of (human) cancer, with critical roles already shown in contributing to tumorigenesis, metastasis, and chemotherapy resistance. Exosomes are detectable in body fluids such as blood, salvia, and urine, making them attractive as biomarkers for early cancer detection, diagnosis, and prognosis, and as therapeutic targets and drug delivery vehicles for cancer therapy.

This Special Issue is calling for reviews and original papers covering translational research on exosomes in cancer from basic science to clinical studies with a strong emphasis on improving the knowledge for clinical application.

Dr. Klaus Holzmann
Dr. Lingeng Lu
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.