Bone and Soft Tissue Tumors: Molecular Mechanisms, Clinical Practice, and Emerging Therapeutics
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".
Deadline for manuscript submissions: 15 June 2025 | Viewed by 8280
Special Issue Editors
Interests: bone and soft tissue sarcoma
Interests: sarcoma; rare cancer; genomics; clinical trial
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Malignant bone and soft tissue tumors are defined as a rare cancer. Since the introduction of perioperative chemotherapy combined with wide surgical excision for several sarcomas, including osteosarcoma and Ewing sarcoma, the prognosis of patients with localized disease has improved. In the past decade, molecular-targeted drugs for soft tissue sarcoma have been developed and used clinically. However, life prognosis, especially for the patients with metastatic or recurrent disease, has not improved in recent decades. As such, novel diagnostic and therapeutic approaches are urgently needed. This Special Issue will focus on recent developments in basic and clinical research for malignant bone and soft tissue tumors. Both original research articles and reviews are welcome. Research topics may include the following:
- Basic research for molecular mechanisms of sarcoma development;
- Molecular-targeted drugs for bone and soft tissue sarcoma;
- Prognostic parameters and biomarkers;
- New imaging modalities;
- New surgical options for local treatment;
- The role of ‘omics’ (genomics, transcriptomics, proteomics, and metabolomics).
We look forward to receiving your contributions.
Prof. Dr. Toshihiro Akisue
Dr. Shintaro Iwata
Dr. Toru Akiyama
Guest Editors
Manuscript Submission Information
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Keywords
- bone and soft tissue sarcoma
- imaging modality
- surgical treatment
- systemic treatment
- molecular-targeted treatment
- biomarkers
- prognostic parameters
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