Immunohistochemistry in Translational Research and Diagnostics of Breast Cancer
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (10 August 2023) | Viewed by 691
Special Issue Editors
Interests: translational research; breast cancer; cancer cell biology; tumour microenvironment (TME); biomarkers; FGF–FGFR signalling
Interests: oncology; pathology; breast cancer; biostatistics; biomarkers; cell cycle; machine learning; artificial intelligence; FGF–FGFR signalling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Human breast cancer (BC) represents a spectrum of tumour subtypes with distinct geno- and phenotypes, natural history and responsiveness to therapy. Although several molecular platforms based on transcriptional profiles have been developed in an attempt to capture and translate this diversity into clinical practice, routine immunohistochemistry still lies at the core of treatment decision making in BC patients. Available survival analyses and clinical data on acquired and/or de novo resistance to therapy indicate, however, that this commonly used, well-established diagnostic tool requires significant tuning. New immunohistochemical markers that will provide criteria for better stratification of patients for specific targeted therapies are urgently needed. The focus of this Special Issue is, therefore, hypothesis-driven research of molecular mechanisms of BC that might result in identification of such biomarkers. Original reports on mechanistic studies of molecular regulators of BC progression and resistance to currently available therapies, evaluating their clinical value as potential subtype-specific immunohistochemical markers of prognosis and prediction in BC, are particularly welcome.
We also invite articles and timely reviews on related topics such as:
- Tumour microenvironment (TME) in BC, its molecular components and immunotherapy
- Cell signalling
- Artificial intelligence and machine learning
- Digital pathology
- Inter- and intratumoural heterogeneity of BC
- Diagnostic techniques, which may serve as valid counterparts for immunohistochemistry in clinic
Dr. Hanna M. Romanska
Dr. Marcin Braun
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- breast cancer
- immunohistochemistry
- biomarker
- prognosis
- cell signalling
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
