Interconnectivity of Cell Death Pathways in Cancer

Dear Colleagues,

Programmed cell death research has encountered major developments over the last two decades. In the past, apoptosis was considered the only mechanistic pathway for regulated cell death, but recently various regulated cell death pathways (i.e., necroptosis, pyroptosis, ferroptosis) have emerged as playing a major role in both normal and pathological conditions. Today, we understand that many cell death pathways are interconnected and this fact may be critical to overcome bacterial resistance or chemoresistance.

This Special Issue plans to give an overview of the most recent advances in the field of programmed cell death and to bring into attention the interconnectivity of cell death pathways. This Special Issue is aimed at stressing the role of different cellular organelles in the cellular decision to succumb or survive upon receiving cell death signal.

Potential topics include, but are not limited to:

• programmed cell death;
• necroptosis;
• apoptosis;
• pyroptosis;
• ferroptosis;
• cell organelles and cell death;
• reversibility of cell death

Dr. Ilana Chefetz
Guest Editor

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