Special Issue "The Role of Integrins in Cancer"
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (15 April 2019).
Interests: integrins; extracellular matrix; cell-matrix interactions; snake venom-derived integrin inhibitors; redox biology
Interests: integrins; extracellular matrix; fibroblasts; cancer-assocaited fibroblasts; collagen; fibrosis
In recent years, our understanding of the molecular events in solid tumors has increased and undergone several dogma shifts. Instead of focusing solely on the mutations, and the effects of these on the inner life of carcinoma cells, the realization has dawned that, for a tumor to grow and spread, the interactions of tumor cells with the tumor microenvironment and the non-tumor cells residing in the tumor milieu are of utmost importance. Current focus in the field concerns the roles of the extracellular matrix, immune cells, cancer associated fibroblasts and vascular cells in creating a permissive environment for tumor growth, tumor spread and chemoresistance.
In the current issue, we will focus on the role of integrins in cancer cells, on immune cells, in cancer-associated fibroblasts and on vascular cells, to orchestrate the events contributing to tumorigenesis and metastasis.
Prof. Dr. Johannes Eble
Prof. Dr. Donald Gullberg
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- molecular mechanism integrins
- tumor microenvironment
- tumor stroma
- cell–matrix interactions