Cancer Pain: From Basic Research to Drug Discovery and Clinical Studies (2nd Edition)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Survivorship and Quality of Life".
Deadline for manuscript submissions: closed (20 September 2025) | Viewed by 254
Special Issue Editor
Interests: capsaicin (vanilloid) receptor TRPV1; "thermoTRP" expression in cancer; TRP channels as oncotargets; TRP chan-nels as tumor suppressors; sensory nerve–tumor interactions; oncothermia
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the second edition of a previous Special Issue entitled “Cancer Pain: From Basic Research to Drug Discovery and Clinical Studies” (https://www.mdpi.com/journal/cancers/special_issues/68V8460N1Q).
Cancer pain is one of the worst forms of chronic pain, with opioids being the mainstay of treatment. Unfortunately, most patients quickly develop opioid tolerance, leaving them with few therapeutic alternatives while battling this deadly disease. Thus, there is an urgent need to identify the molecular mechanisms driving cancer pain to develop novel analgesic drugs. Most cancer pain occurs when the tumor destroys tissues or presses on nerves. However, cancer cells can also produce substances that make normally innocuous stimuli feel painful. Furthermore, therapeutic interventions can induce pain as an adverse effect, as exemplified by chemotherapy-induced peripheral neuropathy.
With this Special Issue, we aim to explore the current state of the cancer pain field, from basic research through to drug discovery and the development to clinical trials. Original research papers, reviews, clinical studies, and meta-analyses of clinical trials are all welcome to contribute.
Dr. Arpad Szallasi
Guest Editor
Manuscript Submission Information
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Keywords
- cancer pain
- drug discovery
- clinical trials
- management
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