Breast Cancer: Prevention and Treatment

Dear Colleagues,

Breast cancer (BC) is the most common tumor among women worldwide. The introduction of well-defined times and methods of screening contributed to a decline in BC mortality rates in high-resource countries. Moreover, in recent years, many efforts have been focused on the study of contemporaneous risk factors, early detection modalities, and novel effective treatments.

The new Special Issue for the journal Cancers, titled “Breast Cancer: Prevention and Treatment”, will focus on both primary and secondary prevention strategies, as well as the different available treatment options. Specifically, the impact of lifestyle, including diet, physical activity, or tobacco use, will be addressed as well as the risk to harbor genetic mutations for BC predisposition and the indication to genetic testing. Moreover, the use of systemic treatment will be argued with a specific focus on the last approved and the ongoing-investigated therapies, together with the recommendations and prevention strategies of specific sub-populations, such us those at increased risk of BC development due to germline mutations. Finally, there will be a focus on (neo)adjuvant trials, which have recently gained increasing attention due to their ability to directly evaluate treatment effects on tumors and their unique translational research potential. Similar to technologies advances from the pre-genomic to the post-genomic era, (neo)adjuvant treatments enable the identification of better predictive biomarkers with personalized treatment strategies, including the post-neoadjuvant/adjuvant setting, particularly in patients with high-risk disease.

Dr. Elisabetta Munzone
Dr. Carmen Criscitiello
Dr. Paola Zagami
Guest Editors

Manuscript Submission Information

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