Special Issue "Sex Differences in Brain Development"
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (15 December 2016).
Steroid hormones play key roles in normal brain development and are necessary for sexual differentiation of brain morphology, as well behavior during critical periods. Neonatal exposure to steroid hormones controls sex-specific development of brain structures (formation, neurogenesis, and apoptosis), and also changes in brain function and behavior (e.g., learning and memory). However, the cellular and molecular mechanisms of steroid hormone action in the brain largely remain unknown. In rodents, hormonal manipulation alone during the neonatal period can reverse sex differences in brain structures and behaviors. However, studies on songbirds suggest that other factors, such as sex-specific gene expression, are also likely to play important roles in sexual differentiation of brain development. Furthermore, exposure to environmental hormone disruptors, as well as other abuse substances, in early life, can affect normal brain development and cause devastating disorders, such as mental retardation, learning disabilities, and other relevant mental diseases, posing strong adverse effects on health.
The purpose of this Special Issue is to bring together studies from diverse backgrounds, in order to provide a broader view of sex differences in brain development and behavior, hopefully shedding some new light on how sex differences in brain development affect mental disorders differently.
Dr. Yu Ping Tang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- sexual dimorphism
- steroid hormone
- gene expression
- neurotrophic factor
- brain development
- mental disorders