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Brain Sciences
Special Issues
Ageing and Geriatric Neuropsychology: Assessment and Intervention
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Ageing and Geriatric Neuropsychology: Assessment and Intervention

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropsychology".

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 2876

Special Issue Editor

Dr. Sara Palermo

E-Mail Website
Guest Editor
1 Department of Psychology, University of Turin, Turin, Italy
2 Neuroradiology Unit, Department of Diagnostic and Technology, Fondazione IRCCS Isttuto Neurologico Carlo Besta, Milan, Italy
Interests: successful ageing; frailty; neurocognitive disorders; neuropsychology; metacogni-tive–executive functions; placebo; pain; neuroimaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Geriatric neuropsychology focuses on the relationship between cognition, the brain, patients' clinical status, and risk and protective factors. Playing a significant role in supporting older adults, it can aid with diagnostic elucidation, including the distinction between cognitive decline associated with normal aging or pathological processes. It can also identify mood alterations and psychopathological processes that compromise autonomy. Additionally, it helps clarify the factors that contribute to successful aging. Geriatric neuropsychology also facilitates the development and implementation of intervention strategies that promote cognitive, emotional, and functional resilience within older adults, providing evidence-based interventions to optimize older adults' quality of life.

This Special Issue will provide a resource for clinicians, incorporating recent research and information from geriatric neuropsychology and related disciplines. Original research and theoretical contributions (reviews, hypotheses, and opinion articles on future directions) are welcome.

Dr. Sara Palermo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ageing
  • frailty
  • neurocognitive disorders
  • dementia
  • cognition
  • behaviour
  • quality of life
  • biomarkers
  • comprehensive geriatric assessment (CGA)
  • prevention (primary secondary and tertiary)

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Published Papers (3 papers)

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Research

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17 pages, 1058 KiB  
Article
Subjective Cognitive Impairment Can Be Detected from the Decline of Complex Cognition: Findings from the Examination of Remedes 4 Alzheimer’s (R4Alz) Structural Validity
by Eleni Poptsi, Despina Moraitou, Emmanouil Tsardoulias, Andreas L. Symeonidis and Magda Tsolaki
Brain Sci. 2024, 14(6), 548; https://doi.org/10.3390/brainsci14060548 - 27 May 2024
Viewed by 876
Abstract
R4Alz is utilized for the early detection of minor neurocognitive disorders. It was designed to assess three main dimensions of cognitive-control abilities: working-memory capacity, attentional control, and executive functioning. Objectives: To reveal the cognitive-control dimensions that can differentiate between adults and older adults [...] Read more.
R4Alz is utilized for the early detection of minor neurocognitive disorders. It was designed to assess three main dimensions of cognitive-control abilities: working-memory capacity, attentional control, and executive functioning. Objectives: To reveal the cognitive-control dimensions that can differentiate between adults and older adults with healthy cognition, people with subjective cognitive impairment, and people diagnosed with mild cognitive impairment by examining the factorial structure of the R4Alz tool. Methods: The study comprised 404 participants: (a) healthy adults (n = 192), (b) healthy older adults (n = 29), (c) people with SCI (n = 74), and (d) people diagnosed with MCI (n = 109). The R4Alz battery was administered to all participants, including tests that assess short-term memory storage, information processing, information updating in working memory, and selective, sustained and divided attention), task/rule-switching, inhibitory control, and cognitive flexibility. Results: A two-factorial structural model was confirmed for R4Alz, with the first factor representing “fluid intelligence (FI)” and the second factor reflecting “executive functions (EF)”. Both FI and EFs discriminate among all groups. Conclusions: The R4Alz battery presents sound construct validity, evaluating abilities in FI and EF. Both abilities can differentiate very early cognitive impairment (SCI) from healthy cognitive aging and MCI. Full article
(This article belongs to the Special Issue Ageing and Geriatric Neuropsychology: Assessment and Intervention)
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12 pages, 740 KiB  
Article
Age-Specific Effects of Visual Feature Binding
by Michelle Werrmann and Michael Niedeggen
Brain Sci. 2023, 13(10), 1389; https://doi.org/10.3390/brainsci13101389 - 29 Sep 2023
Viewed by 1167
Abstract
Temporary binding of visual features enables objects to be stored and maintained in the visual working memory as a singular structure, irrespective of its inherent complexity. Although working memory capacity is reduced in aging, previous behavioral studies suggest that binding is preserved. Using [...] Read more.
Temporary binding of visual features enables objects to be stored and maintained in the visual working memory as a singular structure, irrespective of its inherent complexity. Although working memory capacity is reduced in aging, previous behavioral studies suggest that binding is preserved. Using event-related brain potentials (ERPs), we tested whether stimulus encoding is different in younger (N = 26, mean age = 28.5) and older (N = 22; mean age = 67.4) participants in a change detection task. The processing costs of binding were defined by the difference between feature-alone (color or shape) and feature-binding (color–shape) conditions. The behavioral data revealed that discrimination ability was reduced in the feature-binding condition, and that this effect was more attenuated in older participants. A corresponding ERP effect was not found in early components related to visual feature detection and processing (posterior N1 and frontal P2). However, the late positive complex (LPC) was more often expressed in the feature-binding condition, and the increase in amplitude was more pronounced in older participants. The LPC can be related to attentional allocation processes which might support the maintenance of the more complex stimulus representation in the binding task. However, the selective neural overactivation in the encoding phase observed in older participants does not prevent swap errors in the subsequent retrieval phase. Full article
(This article belongs to the Special Issue Ageing and Geriatric Neuropsychology: Assessment and Intervention)
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Review

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18 pages, 300 KiB  
Review
Spatial Orientation Assessment in the Elderly: A Comprehensive Review of Current Tests
by Panagiota Tragantzopoulou and Vaitsa Giannouli
Brain Sci. 2024, 14(9), 898; https://doi.org/10.3390/brainsci14090898 - 5 Sep 2024
Abstract
Spatial orientation and navigation are complex cognitive functions that integrate sensory information, attention, and memory, enabling individuals to locate themselves in their environment. These abilities decline with age, signaling cognitive impairment in neurological patients, and significantly limit the autonomy of the elderly. Current [...] Read more.
Spatial orientation and navigation are complex cognitive functions that integrate sensory information, attention, and memory, enabling individuals to locate themselves in their environment. These abilities decline with age, signaling cognitive impairment in neurological patients, and significantly limit the autonomy of the elderly. Current neuropsychological assessments fall short in accurately measuring everyday wayfinding abilities, particularly in borderline cases of cognitive decline. This paper reviews various neuropsychological assessments, including Benton’s Judgment of Line Orientation Test, the Almeria Spatial Memory Recognition Test, the Spatial Span subtest from the Wechsler Memory Scale, and the Spatial Orientation in Immersive Virtual Environment Maze Test, evaluating their effectiveness in delineating spatial orientation and navigation skills. The review identifies significant gaps in the validity and reliability of these tests, particularly in their shortened versions, and highlights the potential of virtual reality environments as promising tools for improving diagnostic precision. The findings underscore the need for further research to refine these tools, ensuring they accurately capture cognitive decline and improve the differential diagnosis of neurodegenerative conditions like Alzheimer’s disease. Such advancements hold promise for enhancing the quality of care and autonomy for the elderly. Full article
(This article belongs to the Special Issue Ageing and Geriatric Neuropsychology: Assessment and Intervention)
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