State of the Art in Multisensory Integration: Predicting Age-Related Clinical Outcomes
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Sensory and Motor Neuroscience".
Deadline for manuscript submissions: 1 June 2025 | Viewed by 975
Special Issue Editor
2. Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA
Interests: multisensory integration; sensorimotor integration; aging; translational and clini-cal research; cognitive neuroscience; neuropsychology; executive function; atten-tion; Alzheimer’s disease; motor control; mobility; gait; balance; falls
Special Issue Information
Dear Colleagues,
Our ability to successfully integrate sensory information across multiple modalities is a vital aspect of functioning and mobility in the real world. Age-related sensory impairments have been individually linked to slower gait, functional decline, balance impairments, falls, and a poorer quality of life. Evidence from the Lancet Commissions (2024) has revealed that impairments in hearing, vision and physical inactivity are three of the fourteen potentially modifiable risk factors for dementia. Further, the National Institute on Aging recognizes that functional changes in both the sensory and motor (i.e., non-cognitive) systems impact the development and progression of Alzheimer’s disease and are currently seeking novel, non-cognitive non-invasive predictors to aid in the early detection of Alzheimer’s disease. While it is known that Alzheimer’s disease alters sensory processing, investigations examining the interplay and time course of multisensory, motor and cognitive dysfunction in disease progression are limited. Recent research indicates that visual-somatosensory integration is linked to mobility impairments, mediated by cognitive status, and associated with amyloid burden, suggesting potential value as a novel marker for preclinical Alzheimer’s disease. The main objective of this Special Issue is to showcase state-of-the-art multisensory integration research and highlight its association with various age-related clinical outcomes (including, but not limited to, Alzheimer’s disease, mobility, quality of life, etc.).
Dr. Jeannette R. Mahoney
Guest Editor
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Keywords
- multisensory integration
- sensorimotor integration
- aging
- mobility
- balance
- falls
- cognition
- dementia
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