Protein Folding and Misfolding
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (27 December 2013) | Viewed by 220722
Special Issue Editor
Interests: protein physics; protein structure; protein folding; protein folding intermediates; protein design; phase transitions; phase transition kinetics; transition states; antifreeze proteins; amyloids; protein bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The ability of protein chains to spontaneously form their spatial structures was a long-standing puzzle in molecular biology, especially because the measured rates of spontaneous folding range from microseconds to hours: the difference (at least 11 orders of magnitude) is akin to the difference between the life span of a mosquito and the age of the universe. Now, when this puzzle is solved in its basics, the main interest has been shifted (1) to the "natively disordered" proteins, which usually obtain their definite structure only when interact with target molecules, and (2) to the ability of many protein chains to form not only the "native" (properly working) 3D structures, but also the other ("misfolded") structures, which is also often connected with interaction of these chains with the other molecules.
These reconstructions of protein structures sometimes cause deadly diseases, and therefore the problem of protein folding and misfolding attains a great medical interest. Many new challenges are waiting in the field.
To illustrate for the readers of “Biomolecules” the importance of the protein folding and misfolding problem as a multidisciplinary field of research, this special issue is intended to show the various aspects of protein folding, misfolding and unfolding.
We look forward to reading your contributions.
Prof. Dr. Alexei V. Finkelstein
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- protein folding
- protein misfolding
- protein unfolding
- protein structure
- natively disordered proteins
- protein structure reconstruction
- protein physics
- protein engineering
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.