ncRNA in Cancer and Tissue Regeneration

Dear Colleagues,

Non-coding RNAs are a large class of transcripts that can be classified according to their size, comprising small and long RNAs. Rapid technological advances in high-throughput sequencing revealed several novel non-coding RNAs to be associated with distinct diseases. Non-coding RNAs can control multiple cellular functions and, among their roles, they act on gene regulation at transcriptional and/or posttranscriptional levels. Non-coding RNAs are involved in numerous biological processes and are associated with multifactorial diseases, although most of them are still underexplored.

The role of non-coding RNA in carcinogenesis is a promising and fascinating research field that has attracted a lot of attention. Although most cancer molecular markers are based on coding genome regions, an increasing number of studies show the suitability of non-coding regions, such as non-coding RNAs. On the other hand, non-coding RNAs are emerging as potential tools for tissue regeneration and repair.

There are still a lot of questions to be solved and many new non-coding RNA candidates to be explored. Thus, it is expected that this Special Issue will shed attractive and stimulating new light on various aspects of non-coding RNA mechanisms in carcinogenesis and in tissue regeneration/repair. Additionally, their potential as diagnosis and prognosis markers will also be explored."

Dr. Jaqueline Carvalho De Oliveira
Dr. Daniela Fiori Gradia
Dr. Maria Ines Almeida 
Guest Editors

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