Special Issue "Chromosome Maintenance"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (28 February 2017).
Interests: cell cycle regulated transcription and chromosome maintenance
The eukaryotic cell cycle proceeds through tightly regulated transitions to guarantee that specific events take place in an orderly manner to ensure chromosome maintenance. The high frequency of genetic alterations that affect proteins involved in cell cycle control detected in human tumor cells illustrates the importance of this regulation for faithful cell proliferation. Whilst most of these processes are related to the cell cycle we realize now that a much broader cellular controls are involved in chromosome maintenance. This issue intends to showcase up to date reviews about emerging concepts from future leaders in this exciting area of research.
We thus invite submission review manuscripts (although original research manuscripts are welcome as well) that cover any aspect of chromosome maintenance. This could include DNA replication, DNA repair, the mitotic and meiotic cell cycle, cell motility, cancer evolution and nuclear architecture. Many forms of anti-cancer treatment involve inducing chromosome instability, thus insights into the fundamental mechanisms of chromosome maintenance provides novel therapeutic approaches that will aid the diagnosis and treatment of cancer.
We look forward to reading your contributions.
Prof. Dr. Rob de Bruin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- chromosome maintenance
- DNA replication
- DNA damage
- cell cycle checkpoints
- chromatin structure
- cell motility
- cancer evolution
- nuclear architecture