The Central Nervous System Barriers in Health and Disease

Dear Colleagues,

The central nervous system (CNS) is protected by different barriers that allow its development, maintain its homeostasis, and play a predominant role during diseases. These barriers can be found at the interface between the brain/spinal cord parenchyma and the lumen of blood vessels (blood-brain barrier, blood-spinal cord barrier), the cerebrospinal fluid (CSF) and the choroid plexus blood vessels (blood-CSF barrier), and between the CSF and the meningeal blood vessels (meningeal barrier). In addition, the blood-retinal barrier protects neuronal tissues found in the eyes and the fetal CSF-brain barrier protects the developing CNS. The complexity of these barriers has provided the medical and scientific community with many challenges over the years. Further understanding their intricacies will help on one hand prevent neuroinflammation and restore homeostasis, while, on the other hand, allow targeted access to novel therapeutic approach.

The aim of this special issue of the journal Biomolecules is to highlight biological functions and cell-cell interactions involving these CNS barriers during states of health and disease. Original research manuscripts, reviews and short communications are invited.

Dr. Marc André Lécuyer
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.