The Role of Alarmins and Innate Lymphoid Cells in Allergic Immune Responses
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (30 April 2025) | Viewed by 450
Special Issue Editor
Special Issue Information
Dear Colleagues,
Previously, the pathogenic mechanism of allergy was thought to be an acquired immune response to antigens. However, Moro et al. discovered group 2 innate lymphoid cells (ILC2), which are leukocytes of the innate immune system and are activated by alarmins rather thanantigens, producing type 2 cytokines such as IL-4, IL-5, IL-13 and IL-31, which are involved in the pathogenesis of various type 2 inflammatory and allergic diseases, including atopic dermatitis. Antibody therapy against type 2 cytokines and alarmins has been applied in clinical practice. However, the mechanisms that regulate alarmin itself and how to effectively suppress ILC remain to be elucidated. In addition, the number of papers on ILC and alarmin is still small, despite the attention they have attracted. In this Special Issue, we would like to publish articles that may provide new discoveries, hopes and surprises regarding ILCs, alarmins and allergic diseases.
Dr. Yasutomo Imai
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- innate lymphoid cells
- biologics
- alarmin
- atopic dermatitis
- psoriasis
- asthma
- food allergy
- allergic conjunctivitis
- allergic rhinitis
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
