From Gene to Metabolite: Decoding the Transcriptional Regulatory Networks Controlling the Biosynthesis of Bioactive Compounds
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-derived Molecules".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 77
Special Issue Editor
Interests: regulation of bioactive metabolites in ornamental/medicinal plants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
High-value bioactive compounds are plant-specialized metabolites, providing basic nutritional constituents beyond their unique health benefits. For humans, they display various pharmacological anti-tumor, anti-aging, anti-inflammatory, and anti-cardiovascular disease activities. For plants, they provide abiotic and biotic stress resistance and enable plants to adapt to the environment. The biosynthesis of these bioactive compounds involves a complex transcriptional regulatory network between biosynthetic genes and regulatory elements, with emerging evidence suggesting an integral role for transcription factors. Transcriptional regulation is a critical biological process that allows the plant or organism to respond to a variety of intra- and extra-cellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity.
The present Special Issue welcomes original articles and reviews that focus the exploration of bioactive compound biosynthesis and transcriptional regulation. Studies focusing on how bioactive compounds are regulated by abiotic and biotic factors, exogenous elicitors, and different treatments through high-throughput strategies, including but not limited to genomic, transcriptomic, proteomic, metabolomic, biochemical, molecular, and omics-based techniques, are also welcome.
Dr. Zhenming Yu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bioactive compounds
- transcriptional regulation
- abiotic and biotic factor
- exogenous elicitor
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
