From Gene to Metabolite: Decoding the Transcriptional Regulatory Networks Controlling the Biosynthesis of Bioactive Compounds
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-derived Molecules".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 50
Special Issue Editor
Interests: regulation of bioactive metabolites in ornamental/medicinal plants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
High-value bioactive compounds are plant-specialized metabolites, providing basic nutritional constituents beyond their unique health benefits. For humans, they display various pharmacological anti-tumor, anti-aging, anti-inflammatory, and anti-cardiovascular disease activities. For plants, they provide abiotic and biotic stress resistance and enable plants to adapt to the environment. The biosynthesis of these bioactive compounds involves a complex transcriptional regulatory network between biosynthetic genes and regulatory elements, with emerging evidence suggesting an integral role for transcription factors. Transcriptional regulation is a critical biological process that allows the plant or organism to respond to a variety of intra- and extra-cellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity.
The present Special Issue welcomes original articles and reviews that focus the exploration of bioactive compound biosynthesis and transcriptional regulation. Studies focusing on how bioactive compounds are regulated by abiotic and biotic factors, exogenous elicitors, and different treatments through high-throughput strategies, including but not limited to genomic, transcriptomic, proteomic, metabolomic, biochemical, molecular, and omics-based techniques, are also welcome.
Dr. Zhenming Yu
Guest Editor
Manuscript Submission Information
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Keywords
- bioactive compounds
- transcriptional regulation
- abiotic and biotic factor
- exogenous elicitor
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