Assembly of RNA and DNA

Dear Colleagues,

We are pleased to invite you to contribute to a dedicated exploration of processes and conditions that allow RNA and DNA assemblage. It has been preliminary assumed that RNA and DNA polymerization resulted from the rotational friction of ions and the electric–magnetic processing of electronegative elements dissolved in saline water generated by rising bubbles in the early hot ocean. It has also been hypothesized that bubbles mediated the acceleration of ions intercepted into bubble convex and concave boundaries, which then decelerated within bubble vortices, allowing for their polarization and then rotational–electrodynamic condensation into elongated, spiral polymers. Once assembled, first as RNA and then DNA, these polymers acted as a universal electrodynamic template, enabling the assembly of more complex "informative molecules" which participate in the ongoing creation and evolution of diverse forms of life. Further gathering experimental evidence and theoretical knowledge along this line of research is fundamental. We hope to make progress in understanding the origin of life and elucidating the diverse rotational–electric interactions that are particularly important for further progress in biology, medicine, and humanity overall

This Special Issue aims to approach the interrelation between the physical and chemical fields and the processes responsible for the rotational–electric polarization of electronegative H, C, N, O, and P atoms and their related condensation into elongated self-replicating polymers. In particular, the rotational–electric assemblage of RNA and its rotational–electric functioning at a molecular scale fall within the immediate scope of this Special Issue. Therefore, the proposed Special Issue is dedicated to exploring the electric properties of RNA/DNA operating as an extremely precise (rotational–electric) molecular system responsible for internal and external interactions, as new knowledge on RNA and DNA assemblage may have important biological and medical implications. Experimental and mathematical investigations, as well as theoretical studies, are welcome.

In this Special Issue, original research articles and reviews are welcome on research areas that may include (but are not limited to) the following:

• Ocean-inspired molecules;
• Bubble-mediated polymerization;
• Molecular electric structure and dynamics;
• Generation of electrons in nucleotides;
• Transfer of electrons in biomolecules;
• Cyclic flows of electrons in biomolecules;
• Molecular electro-biochemistry;
• Rotational–electric reproduction;
• Rotational–electric transport of ions;
• Molecular biophysics.

We look forward to receiving your contributions.

Prof. Dr. Roman Marks
Prof. Dr. Jürg Bähler
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• polymerization of RNA and DNA
• electrical functioning of RNA/DNA
• rotational–electric principles of replication
• interactions between RNA/DNA and physical/chemical field
• chirality in biomolecules