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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gastric Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatment

edited by Sharona B. Ross

submission deadline 28 Feb 2026 | 1 articles | Viewed by 723 | Submission Open

Keywords: gastric cancer; tumor microenvironment; molecular mechanism; targeted therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Nervous System Injury and Repair: From Molecular Mechanism to Therapeutic Perspectives

edited by

Shuchao Wang

submission deadline 28 Feb 2026 | 1 articles | Viewed by 623 | Submission Open

Keywords: nervous system injury; neuron; astrocytes; microglial cells; excitotoxicity; inflammation; oxidative stress; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Thyroid Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatment

edited by Sonam Kumari

submission deadline 28 Feb 2026 | 1 articles | Viewed by 572 | Submission Open

Keywords: radioactive iodine (RAI) treatment; tyrosine kinase inhibitors (TKIs); biomarkers; radiolabeled peptides; diagnostic markers; molecular targets; metastatic progressive thyroid cancer; overcoming resistance; personalized therapies; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Multidisciplinary Approaches to Neurodegenerative Disorders

edited by

Toomas Toomsoo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 546 | Submission Open

Keywords: neurodegenerative disorders; lipid metabolism; comorbidity patterns super-agers; precision medicine; biomarker discovery; AI-assisted diagnostics; translational neuroscience; multi-omics integration; neuroinflammation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Peptide Therapeutic Approaches for Cancer Treatment

edited by

Prakash Lingasamy

and

Vijayachitra Modhukur

submission deadline 28 Feb 2026 | Viewed by 522 | Submission Open

Keywords: peptide therapeutics; cancer treatment; drug delivery systems; molecular imaging; bioinformatics; machine learning and artificial intelligence (AI); therapeutic targeting; peptide– drug conjugates; personalized medicine; immunotherapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Adipokines (3nd Edition)

edited by

Christa Büchler

submission deadline 28 Feb 2026 | Viewed by 522 | Submission Open

Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Pulmonary Fibrosis

edited by

Mari Ozaki

submission deadline 28 Feb 2026 | 1 articles | Viewed by 495 | Submission Open

Keywords: pulmonary fibrosis; interstitial lung disease; antifibrotic therapy; precision medicine; imaging diagnostics; novel therapeutics; pathobiology; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

Demyelinating Diseases: Pathophysiology and Emerging Therapeutic Targets

edited by Jude Taylor

submission deadline 28 Feb 2026 | Viewed by 416 | Submission Open

Keywords: demyelinating diseases; pathophysiological processes; diagnostic accuracy and predicting disease; emerging strategies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Recent Advances in Primary and Relapsed Ovarian Cancer

edited by Cornelia Bachmann

submission deadline 28 Feb 2026 | Viewed by 372 | Submission Open

Keywords: ovarian cancer; relapse; BRCA; genetics; immunotherapy; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

The Role of Environmental Pollutants in Cancer and Chemoresistance

edited by

Fabio Altieri

and

Margherita Eufemi

submission deadline 28 Feb 2026 | Viewed by 364 | Submission Open

Keywords: environmental pollutants; cancer cells; therapeutic agents

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances of Amyloid-β Dynamics in Health and Diseases

edited by

Rahat Ullah

submission deadline 28 Feb 2026 | Viewed by 353 | Submission Open

Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Recent Advances in Biomedical Engineering for the Elderly

edited by

Siti Anom Ahmad

submission deadline 28 Feb 2026 | Viewed by 241 | Submission Open

Keywords: biomedical engineering; gerontechnology; artificial intelligence in healthcare; digital health; physiological signal processing; human– machine interaction; rehabilitation engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Cancer Treatment

edited by

Vlasios Karageorgos

and

George Liapakis

submission deadline 28 Feb 2026 | Viewed by 215 | Submission Open

Keywords: targeted therapy; bio-conjugates; biologic agents; precision oncology; personalized cancer treatment; biomarker-guided therapy; cancer drug development; biopharmaceuticals

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis, Diagnosis and Treatment of Endocrine Cancers

edited by

Rajeev Parameswaran

submission deadline 28 Feb 2026 | Viewed by 199 | Submission Open

Keywords: thyroid; parathyroid; adrenal; paraganglioma; genomes; transcriptomes; signalling pathways; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Cannabinoids in Therapeutics: Mechanisms, Signaling Pathways and Personalized Treatment Strategies

edited by

Jan Rožanc

and

Uroš Maver

submission deadline 28 Feb 2026 | Viewed by 197 | Submission Open

Keywords: cannabinoids; endocannabinoid system; cancer; pain; inflammation; personalized medicine; receptor signaling; therapeutic development; drug delivery; pharmacogenomics; systems pharmacology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Single-Cell and Spatial Transcriptomics: Decoding Tumor Heterogeneity and Microenvironment

edited by

Guanhu Yang

submission deadline 28 Feb 2026 | Viewed by 192 | Submission Open

Keywords: single-cell sequencing; spatial transcriptomics; tumor microenvironment; heterogeneity; immunotherapy resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Current Challenges and Future Trends in Intracranial Aneurysms: Mechanisms, Biomarkers, and Therapeutic Strategies

edited by Zhongsong Shi and

Aichi Chien

submission deadline 28 Feb 2026 | Viewed by 176 | Submission Open

Keywords: intracranial aneurysm; subarachnoid hemorrhage; inflammation; immune; smooth muscle cell; endothelial dysfunction; hemodynamic forces; biomarkers; neuroimaging; non-coding RNA; multi-omics; endovascular treatment; computational fluid dynamic

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diagnostic and Therapeutic Approaches to Pancreatic Cancer—Second Edition

edited by

Sanchita Rauth

submission deadline 28 Feb 2026 | Viewed by 168 | Submission Open

Keywords: pancreatic cancer; systemic therapy; immunotherapy; tumor microenvironment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Glioblastoma: From Pathology to Novel Therapeutic Approaches

edited by Carlen A. Yuen

submission deadline 28 Feb 2026 | Viewed by 163 | Submission Open

Keywords: glioblastoma; EGFR; TERT; +7/-10; CAR T-cell therapy; immunotherapy; GammaTile® ; LITT

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Fertility and Reproductive Health: Understanding of Reproductive Physiology and Pathology

edited by Sevastiani Antonouli and

Valentina Di Nisio

submission deadline 28 Feb 2026 | Viewed by 157 | Submission Open

Keywords: female infertility; male infertility; oocyte quality; embryo implantation; follicular dynamics; gamete and embryo ultrastructure; assisted reproduction technologies; reproductive aging; fertility preservation; oncofertility challenges

(This special issue belongs to the Section Gene and Cell Therapy)

New Insights into Breast Cancer Management: From Tumorigenesis to Personalized Treatments—2nd Edition

edited by

Rita De Sanctis

and

Paola Tiberio

submission deadline 28 Feb 2026 | Viewed by 145 | Submission Open

Keywords: breast cancer; diagnosis; prognosis; treatment response prediction; biomarkers; risk factors; new therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

Neurotrauma: Mechanisms, Pathways, and Emerging Therapeutic Interventions, 2nd Edition

edited by Kevin Pierre and

Brandon Lucke-Wold

submission deadline 28 Feb 2026 | Viewed by 145 | Submission Open

Keywords: neurotrauma; traumatic brain injury; spinal cord injury; inflammation; oxidative stress; excitotoxicity; diagnostic biomarkers; imaging techniques; neuroprotection; neurogeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Novel Insight into Human Reproductive Medicines

edited by

Bo Huang

submission deadline 28 Feb 2026 | Viewed by 145 | Submission Open

Keywords: IVF; oocyte; sperm; clinical outcome; embryo; ovulation induction; fertilization; PGT

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Immune and Metabolic Dysregulation in Neurological and Neuropsychiatric Disorders

edited by

Qingkun Liu

and

Xin-An Liu

submission deadline 28 Feb 2026 | Viewed by 142 | Submission Open

Keywords: neuroimmune interaction; neuroinflammation; metabolic regulation; gut– brain axis; microbiome; neuroendocrine system; neurodegeneration; psychiatric disorders; brain injuries

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Innovative Strategies for the Diagnosis and Treatment of Sarcopenia and Osteoporosis

edited by Wei-Bin Hsu and

Meng-Huang Wu

submission deadline 28 Feb 2026 | Viewed by 141 | Submission Open

Keywords: sarcopenia; osteoporosis; healthy aging; bone strength; muscle health; fracture prevention; pharmacological therapies; nutritional support; exercise rehabilitation

(This special issue belongs to the Section Molecular and Translational Medicine)

Neuroimmunology and Neurological Infection

edited by

Mariya Ivanovska

submission deadline 28 Feb 2026 | Viewed by 140 | Submission Open

Keywords: neuroimmunology; neurological infections; immune-mediated diseases; neurodegeneration; biomarkers; immunotherapy; neuroinflammation; clinical neurology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Kidney Disease: From Pathophysiology to Treatment

edited by

Paola Pontrelli

and

Francesca Conserva

submission deadline 28 Feb 2026 | Viewed by 133 | Submission Open

Keywords: acute kidney injury; chronic kidney disease; precision medicine; molecular mechanisms; biomarkers; therapeutic response

Drug Resistance and Novel Targets for Cancer Therapy—Third Edition

edited by

Bruno Kaufmann Robbs

and

Fernando de Carvalho da Silva

submission deadline 28 Feb 2026 | Viewed by 129 | Submission Open

Keywords: cancer; drug resistance; targeted therapy; conventional chemotherapy; natural products; molecular targets; cancer hallmarks; therapeutic agents

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Diagnosis and Therapeutic Strategies in Intraocular Inflammation—Second Edition

edited by

Uwe Pleyer

submission deadline 28 Feb 2026 | Viewed by 128 | Submission Open

Keywords: biomarker; diagnosis; immune pharmacology; immune regulation; immune system; infection; uveitis; therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Human Stem Cells in Disease Modelling and Treatment (2nd Edition)

edited by Sofia M. Calado and

Álvaro Plaza Reyes

submission deadline 28 Feb 2026 | Viewed by 126 | Submission Open

Keywords: induced pluripotent stem cells (iPSCs); embryonic stem cells (ESCs); disease models; cell therapies; cell therapy medicinal products (CTMPs); regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

Anticancer Drugs in Immunotherapy: Molecular Mechanisms, Translational Insights, and Clinical Applications

edited by

Bashir Lawal

submission deadline 28 Feb 2026 | Viewed by 115 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitors; drug synergy; immunogenic cell death; tumor microenvironment; cancer immunology; combination therapy; chemotherapy; targeted therapy; translational oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Eicosanoids and Fatty Acids in Health, Diseases and Therapeutics

edited by Mihai Nechifor

submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open

Keywords: eicosanoids; prostaglandins; leukotrienes; prostacyclin; lipoxins; resolvins; protectins; maresins; arachidonic acid (AA); eicosapentaenoic acid (EPA); docosahexaenoic acid (DHA); cell functions; immunity; cardiovascular; neuropsychiatric; metabolic; digestive; reproductive; hematologic; inflammatory and oncologic pathology; therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Emerging Technologies in Liquid Biopsy of Cancers

edited by Lingdi Yin

submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open

Keywords: liquid biopsy; circulating tumor cells (CTCs); circulating tumor DNA (ctDNA); exosomes; cancer diagnostics; biomarker discovery; minimally invasive monitoring; emerging technologies; clinical translation; molecular profiling

(This special issue belongs to the Section Cancer Biology and Oncology)

Pyroptosis and Cellular Stress: Emerging Mechanisms and Therapeutic Targets

edited by Gang Du

submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open

Keywords: pyroptosis; cellular stress; ROS; programmed cell death; gasdermin; cytokines; inflammation; infection; cellular metabolism; immunometabolism

(This special issue belongs to the Section Cell Biology and Pathology)

Decoding Resistance: Molecular Drivers of Therapy Failure in Advanced Prostate Cancer

edited by

Jyoti Kaushal

submission deadline 28 Feb 2026 | Viewed by 112 | Submission Open

Keywords: prostate cancer; androgen deprivation therapy; molecular signaling; epigenetic remodeling; cancer stem cell; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Emerging Trends in Dental Caries: Insights into Etiology, Risk Factors, and Treatment Strategies (2nd Edition)

edited by

Hee-Eun Kim

submission deadline 28 Feb 2026 | Viewed by 111 | Submission Open

Keywords: antimicrobial effect; demineralization; dental caries; dental plaque; oral biofilm; oral disease; oral management; pathogenicity; prevention; remineralization

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Intestinal Homeostasis and Disease Dysbiosis

edited by

Nikolas Dovrolis

submission deadline 28 Feb 2026 | Viewed by 105 | Submission Open

Keywords: gut microbiota; intestinal homeostasis; dysbiosis; microbiota– drug interactions; host– microbe interactions; microbiome therapeutics; precision medicine

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Diagnostics in Diabetes: From Biomarkers to Clinical Applications

edited by

Robert Stawski

and Konrad Walczak

submission deadline 28 Feb 2026 | Viewed by 104 | Submission Open

Keywords: diabetes; molecular diagnostics; cell-free DNA (cfDNA); microRNAs; circulating biomarkers; diabetes complications; personalized therapy

(This special issue belongs to the Section Cell Biology and Pathology)

Diagnosis and Treatment of Periodontal Disease

edited by

Khaing Myat Thu

submission deadline 28 Feb 2026 | Viewed by 102 | Submission Open

Keywords: periodontitis; gingivitis; periimplantitis; artificial intelligence; X-ray; periodontal treatment; plaque control; oral hygiene

(This special issue belongs to the Section Molecular and Translational Medicine)

Immunotherapy and Immune-Related Adverse Events in Cancer

edited by

Ivana Mikolašević

and

Marin Golčić

submission deadline 28 Feb 2026 | Viewed by 102 | Submission Open

Keywords: immunotherapy; cancer; PD-1 inhibitors; immune-related adverse effects; management

(This special issue belongs to the Section Immunology and Immunotherapy)

Research Progress on Antimicrobial Resistance (AMR)

edited by

Tomohiro Oishi

submission deadline 28 Feb 2026 | Viewed by 99 | Submission Open

Keywords: antimicrobial resistance; mechanism; therapy; experiment; bacteria; antibiotics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Liver Fibrosis: From Mechanisms to Therapeutics

edited by

Kun Zhang

submission deadline 28 Feb 2026 | Viewed by 97 | Submission Open

Keywords: liver fibrosis; therapeutic target; biomarker; hepatocyte; macrophage; LSEC; HSC; immune cells; extracellular matrix

(This special issue belongs to the Section Molecular and Translational Medicine)

Liver Cancer: Molecular and Translational Insights of Carcinogenesis and Treatments

edited by

Joon Hyuk Choi

submission deadline 28 Feb 2026 | Viewed by 96 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; intrahepatic cholangiocarcinoma; carcinogenesis; premalignant lesions; diagnosis; pathology; treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Encephalitis and Viral Infection: Mechanisms and Therapies—2nd Edition

edited by Bradley S. Hollidge and

Samantha S. Soldan

submission deadline 28 Feb 2026 | Viewed by 95 | Submission Open

Keywords: neurovirology; encephalitis; gene therapy; viral vectors; virology; immunology; neuroscience; gene editing; neuroinflammation; arboviruses; innate immunity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Thyroid Disease: From Mechanism to Therapeutic Approaches (2nd Edition)

edited by

Beata Wojtczak

submission deadline 28 Feb 2026 | Viewed by 94 | Submission Open

Keywords: pathogenesis and molecular mechanism of thyroid diseases; genetic disorders of the thyroid; biomarkers for thyroid dysfunctions; diagnostic challenges; new thyroid’ s therapies; immunotherapy; nuclear medicine; minimally invasive treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Generative Artificial Intelligence in Biomedical Sciences: Transforming Research, Diagnosis, and Therapy

edited by Iman Tavassoly

submission deadline 28 Feb 2026 | Viewed by 90 | Submission Open

Keywords: artificial intelligence; biomedical data; generative models; machine learning; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

The Tumor Microenvironment and Heterogeneity: Challenges and Opportunities in Multiple Myeloma Immunotherapy

edited by

Enze Liu

submission deadline 28 Feb 2026 | Viewed by 89 | Submission Open

Keywords: multiple myeloma; immunotherapies; tumor microenvironment; novel targets; surfaceome; expression heterogeneity

(This special issue belongs to the Section Cancer Biology and Oncology)

Anti-Cancer Agents: Synthesis and Evaluation of Pharmacological Activity

edited by Sureshbabu Popuri

submission deadline 28 Feb 2026 | Viewed by 87 | Submission Open

Keywords: anticancer agents; synthesis; pharmacological evaluation; medicinal chemistry; small molecules; metal complexes; structure– activity relationship (SAR); cytotoxic activity; apoptosis; drug discovery; chemotherapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

State of the Art in Mitochondrial Research

edited by

Jan Ježek

submission deadline 28 Feb 2026 | Viewed by 82 | Submission Open

Keywords: mitochondrial metabolism; bioenergetics; mitochondrial signaling; mitochondrial dynamics; reactive oxygen species; apoptosis; hypoxia; mitochondrial genetics; mitochondrial diseases; aging

(This special issue belongs to the Section Cell Biology and Pathology)

Contribution of Neural Stemness and Its Regulatory Networks to Tumorigenesis

edited by

Ying Cao

submission deadline 28 Feb 2026 | Viewed by 79 | Submission Open

Keywords: neural stemness; tumorigenicity; pluripotency; phenotypic heterogeneity; cancer cell; cancer cell-intrinsic neural factors; differentiation therapy via targeting neural stemness; tumorigenesis; therapy resistance; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

Displaying special issue 351-400 on page 8 of 15.

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