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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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MicroRNAs in Precision Medicine: Regulation, Biomarkers and Novel Therapeutics

edited by Shing Cheng Tan

submission deadline 31 Dec 2025 | Viewed by 89 | Submission Open

Keywords: MicroRNAs; non-coding RNAs; biomarkers; therapeutic targets; cancer; omics technologies; precision medicine; disease pathogenesis

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis and Novel Diagnostic Techniques in Juvenile Idiopathic Arthritis—Second Edition

edited by

Katarzyna Winsz-Szczotka

submission deadline 31 Dec 2025 | Viewed by 89 | Submission Open

Keywords: juvenile idiopathic arthritis; pathogenesis; cartilage and bone anabolism and catabolism; diagnostics; treatment; prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetics in Human Cancer: Emerging Biomarkers and Therapeutic Targets

edited by

Jeong-yeon Lee

submission deadline 31 Dec 2025 | Viewed by 84 | Submission Open

Keywords: cancer; epigenetics; DNA methylation; histone modification; chromatin remodeling; non-coding RNAs; therapeutic resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis and Therapeutic Intervention of Alzheimer's Disease

edited by Chanchal Sharma

submission deadline 31 Dec 2025 | Viewed by 74 | Submission Open

Keywords: dementia; Alzheimer’ s disease; neuroinflammation; microglia; gene therapy; stem cells; blood– brain barrier; oxidative stress; gut-microbiome; diet; artificial intelligence

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Genetic Research on Colorectal Cancers

edited by

Wangxiong Hu

submission deadline 31 Dec 2025 | Viewed by 71 | Submission Open

Keywords: high microsatellite instability; epigenetic age acceleration; spatial omics and single-cell sequencing; cold tumors and immunotherapy; driver gene; DNA replication repair; liquid biopsy; ctDNA

(This special issue belongs to the Section Cancer Biology and Oncology)

Vitamin D in Health and Disease (4th Edition)

edited by

Giuseppe Murdaca

submission deadline 31 Dec 2025 | Viewed by 67 | Submission Open

Keywords: vitamin D and the immune system; vitamin D and cytokines; vitamin D and microbiome; vitamin D and respiratory diseases; vitamin D and autoimmune diseases; vitamin D and allergies

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Pathogenesis and Treatment of Infectious Diseases

edited by Francesca Gioia

submission deadline 31 Dec 2025 | Viewed by 66 | Submission Open

Keywords: antimicrobial resistance; phage therapy; host– pathogen interactions; molecular diagnostics; immunotherapy

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Pathomechanisms of Disturbances Underlying Chronic Disorders—Third Edition

edited by

Dorota Formanowicz

submission deadline 31 Dec 2025 | Viewed by 64 | Submission Open

Keywords: chronic disorders; atherosclerosis; inflammation; oxidative stress; lipoproteins; endothelial dysfunction; biomarkers; pathomechanisms

(This special issue belongs to the Section Immunology and Immunotherapy)

Signaling of Protein Kinases in Development and Disease (2nd Edition)

edited by

John Zheng Fu

submission deadline 31 Dec 2025 | Viewed by 64 | Submission Open

Keywords: kinase; phosphorylation; signaling; mutation; mechanism; development; inhibitor; disease

(This special issue belongs to the Section Cell Biology and Pathology)

Novel Drug Delivery Systems: Design, Evaluation and Application: 2nd Edition

edited by

Yongtai Zhang

submission deadline 31 Dec 2025 | Viewed by 61 | Submission Open

Keywords: pharmaceutics; drug delivery systems; nanoparticles; nanomedicine; biomolecules; hydrogels; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Chondrocyte Biology (2nd Edition)

edited by

Bo Qiu

submission deadline 31 Dec 2025 | Viewed by 59 | Submission Open

Keywords: osteoarthritis; chondrocyte; differentiation; proliferation; signaling pathways; transcription factor; inflammation; cellular processes; cartilage repair

(This special issue belongs to the Section Cell Biology and Pathology)

Inflammation in Neurogenerative Diseases: Mechanisms and Therapeutic Frontiers

edited by

Shao-Bin Wang

submission deadline 1 Jan 2026 | Viewed by 81 | Submission Open

Keywords: neuroinflammation; neurodegenerative diseases; biomarkers mitochondria dysfunction; microglia; immune response; therapeutic development; gene therapy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticles for Glioblastoma Therapy

edited by Shambhavi Pandey and

Benjamí Oller-Salvia

submission deadline 20 Jan 2026 | Viewed by 59 | Submission Open

Keywords: nanoparticles; blood& ndash; brain barrier; gene delivery; glioblastoma; cancer stem cells; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Prostate Cancer: From Pathology to Novel Therapeutic Approaches (2nd Edition)

edited by

Gvantsa Kharaishvili

submission deadline 30 Jan 2026 | 1 articles | Viewed by 2179 | Submission Open

Keywords: prostate cancer; castration-resistant prostate cancer; metastatic disease; biomarker; tumor microenvironment; treatment; immunotherapy; drug resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Feature Reviews in Cytokines

edited by

Monika Zajkowska

submission deadline 30 Jan 2026 | 2 articles | Viewed by 1489 | Submission Open

Keywords: cytokines; neurodegenerative disease; cancer; diabetes; obesity; immunological disorder; cardiovascular disease; diagnosis; biomarker; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms of Cell Death in Cancer Cells: A New Therapeutic Opportunity—2nd Edition

edited by

Adrian-Bogdan Țigu

submission deadline 31 Jan 2026 | 6 articles | Viewed by 15298 | Submission Open

Keywords: cell death; drug repositioning; translational research; oncology; cancer therapy; apoptosis

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Biomarkers in Inflammatory Bowel Disease: Pathophysiology and New Therapeutic Strategies—Second Edition

edited by

Marino Vilović

submission deadline 31 Jan 2026 | 5 articles | Viewed by 12228 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; biomarkers; molecular biomarkers in IBD; pathophysiology; therapeutic approaches in IBD; precision medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiovascular and Metabolic Disease: New Treatment and Future Directions—4th Edition

edited by

Alfredo Caturano

submission deadline 31 Jan 2026 | 11 articles | Viewed by 11712 | Submission Open

Keywords: cardiovascular disease; metabolic disease; diabetes; therapy; drugs; implantable device; heart failure; heart transplantation; cardiac surgery; future directions

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Research of Neurodegenerative and Psychiatric Diseases, 2nd Edition

edited by

Dubravka Švob Štrac

submission deadline 31 Jan 2026 | 6 articles | Viewed by 10383 | Submission Open

Keywords: neurodegenerative disorders; psychiatric diseases; biomarkers; therapeutic targets; omics approaches; molecular pathways; cell biology; animal models; clinical studies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Mechanisms and Novel Therapies for Brain Injury: 2nd Edition

edited by

Arjun Sapkota

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8076 | Submission Open

Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood– brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticle-Based Drug Delivery in Cancer Therapy: Current Progress and Challenges

edited by

Menghuan Tang

and

Zhaoqing Cong

submission deadline 31 Jan 2026 | 3 articles | Viewed by 7310 | Submission Open

Keywords: nanoparticle; targeted drug delivery; controlled release; clinical translation; drug resistance; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Therapeutic Potential for Cannabis and Cannabinoids, 3rd Edition

edited by

Wesley M. Raup-Konsavage

submission deadline 31 Jan 2026 | 2 articles | Viewed by 6502 | Submission Open

Keywords: cannabis; tetrahydrocannabinols (THC); cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN); cannabichromene (CBC); pain; cancer; anxiety; PTSD; sleep disorders; neuroprotection; anti-inflammatory

(This special issue belongs to the Section Molecular and Translational Medicine)

Hypertension and Chronic Renal Failure

edited by

Caterina Carollo

submission deadline 31 Jan 2026 | 4 articles | Viewed by 6399 | Submission Open

Keywords: hypertension; chronic renal failure; NephroCardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering

edited by

Andrei Vasile Nastuta

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6193 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy

(This special issue belongs to the Section Molecular and Translational Medicine)

Triple Negative Breast Cancer: From Mechanisms to Therapeutic Approaches

edited by Emad Rakha and Padmashree Rida

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6144 | Submission Open

Keywords: triple-negative breast cancer; neoadjuvant; adjuvant; chemotherapy; immunotherapy; antibody– drug conjugates; immune checkpoint inhibitors; DNA damage; EGFR; FGFR; microtubule dynamics; centrosome amplification

(This special issue belongs to the Section Cancer Biology and Oncology)

Medicinal Chemistry in Drug Design and Discovery, 2nd Edition

edited by

Małgorzata Jarończyk

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4468 | Submission Open

Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4136 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

PPARs in Health and Disease, 2nd Edition

edited by

Maria Konstandi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3722 | Submission Open

Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3401 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Infection and Immunity

edited by

Vijay Singh Gondil

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3378 | Submission Open

Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition

edited by

Wen-Lin Su

, Chih-Hao Shen,

Sheng-Kang Chiu

and

Yi-Ting Chen

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3206 | Submission Open

Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3202 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes

edited by

Xian (Phoebe) Zhou

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3189 | Submission Open

Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Human Reproductive Biology

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3034 | Submission Open

Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty

(This special issue belongs to the Section Molecular and Translational Medicine)

Infectious Diseases: Prevention, Diagnosis, and Treatment Under Antimicrobial Resistance Global Urgency

edited by

Célia F. Rodrigues

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3015 | Submission Open

Keywords: AMR; infectious diseases; bacteria; fungi; alternative treatment

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders

edited by Raffaella Cascella

submission deadline 31 Jan 2026 | 4 articles | Viewed by 2978 | Submission Open

Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in Genetic Research and Molecular Diagnostics for Hematological Diseases

edited by Ying S. Zou and Leonard N. Yenwongfai

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2876 | Submission Open

Keywords: hematological diseases; genetic research; benign hematology; inherited disorders; next-generation sequencing/long-read sequencing; optical genome mapping; transcriptome; proteomics; digital pathology; deep convolutional neural networks

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Role of Glycomics in Health and Diseases

edited by

Tijl Vermassen

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2554 | Submission Open

Keywords: glycomics; protein chemistry; tumor immunology; biomarker research

(This special issue belongs to the Section Molecular and Translational Medicine)

Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition

edited by

Kristina Pilipović

and

Petra Dolenec

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2544 | Submission Open

Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

edited by Ilaria Dentamaro

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2494 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Exploring Potential Therapeutic Compounds with Anti-Inflammatory Activity

edited by Shomaila Mehmood

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2199 | Submission Open

Keywords: green tea polyphenols; isoflavanoids; resveratrol; curcumin; genistein; melatonin; antioxidants; metalloporphyrins; anti-inflammatory compounds

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions

edited by

Azizah Ugusman

, Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2058 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

The Molecular Basis of the Immune Response in Pulmonary Fibrosis

edited by

Tamara Cruz

and

Fernanda Hernandez

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1907 | Submission Open

Keywords: immune response; fibrosis; aging; senescence

(This special issue belongs to the Section Immunology and Immunotherapy)

Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies

edited by

Deepti Diwan

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1830 | Submission Open

Keywords: neurovascular; blood vessels; nervous system; neurological diseases

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1788 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Therapeutic Strategies in Gynecological Malignant Tumors—2nd Edition

edited by

Alberto Farolfi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1669 | Submission Open

Keywords: targeted therapy; precision medicine; gynecological cancers; ovarian cancer; endometrial cancer; cervical cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition

edited by

Kan Katayama

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1564 | Submission Open

Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular and Translational Medicine)

Clinical, Radiological, and Molecular Insights into Craniopharyngioma

edited by Ernest Jan Bobeff and

Bartosz Szmyd

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1387 | Submission Open

Keywords: neuro-oncology; brain tumors; skull base; craniopharyngioma; stalk

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neural Nexus: Interdisciplinary Perspectives on Neurological Disorders

edited by Gianandrea Traversi,

Marianna Mazza

and Giuseppe Marano

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1313 | Submission Open

Keywords: neurological disorders; mental health; artificial intelligence; machine learning; biomarkers; drug discovery; therapeutic targets; neuroscience research

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Recent Advances in Targeted Drug Delivery Systems

edited by

Santosh Bashyal

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1154 | Submission Open

Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Displaying special issue 351-400 on page 8 of 16.

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