Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management
edited by and Sérgio Laranjo
submission deadline 31 May 2026 | Viewed by 326 | Submission Open
Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)
(This special issue belongs to the Section Neuroscience)
Machine Learning Advanced Research on Ecosystem Carbon and Nitrogen Cycles
edited by Fenghui Yuan and
submission deadline 31 May 2026 | Viewed by 145 | Submission Open
Keywords: machine learning; biogeochemical cycles; ecosystem modeling; carbon cycling; nitrogen cycling; greenhouse gas; climate change; land-use change; data assimilation
(This special issue belongs to the Section Ecology)
Pluripotent Stem Cells in Development and Disease
edited by
submission deadline 31 May 2026 | Viewed by 138 | Submission Open
Keywords: pluripotent stem cells (PSCs); early development; regenerative medicine; genetic/epigenetic factors; differentiation; cell fate determination; disease modelling; organoids; genomic editing; single-cell omics
(This special issue belongs to the Section Developmental and Reproductive Biology)
Studies on Insect Genetics and Genomics
edited by Ying Lin
submission deadline 31 May 2026 | Viewed by 118 | Submission Open
Keywords: novel sequencing technologies; genome-editing methods; sex chromosome origins; horizontal gene transfer; resource insects; eco-friendly insect control technologies; genomics; ecology; molecular biology; insect
(This special issue belongs to the Section Genetics and Genomics)
Animal Models for Immune and Infectious Diseases
edited by Shijun Zheng
submission deadline 31 May 2026 | Viewed by 105 | Submission Open
Keywords: animal models; immune responses; autoimmunity; infectious diseases; host– pathogen interaction; immunotherapies
Wetland Ecosystems (2nd Edition)
edited by , Chenglang Pan and Qiang Wang
submission deadline 1 Jun 2026 | 16 articles | Viewed by 33415 | Submission Open
Keywords: biological invasion; pollution; carbon sink function; the biogeochemical cycle of biogenic elements; population and community ecology; global climate change; coastal zone management; the structure and function of the microbiome; environmental adaptation mechanisms of wetland organisms; wetland landscape; wetland degradation
(This special issue belongs to the Section Ecology)
Animal Models of Neurodegenerative Diseases
edited by Xiangyu Guo
submission deadline 1 Jun 2026 | 6 articles | Viewed by 15978 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; Parkinson's disease; Huntington's disease; neuroscience; animal models; pathogenesis
(This special issue belongs to the Section Neuroscience)
Biomarkers in Stress Biology and Ecology submission deadline 1 Jun 2026 | 3 articles | Viewed by 9108 | Submission Open
Keywords: biomarkers; ecotoxicology; environmental contamination; stress ecology; neurotoxicity; oxidative stress; pollution
Interactions and Cross-Kingdom Regulation of Hosts and Pathogens/Parasites
edited by and Jianfeng Qiu
submission deadline 1 Jun 2026 | Viewed by 146 | Submission Open
Keywords: host; pathogen; parasite; interaction; cross-kingdom regulation; immune response; infection
(This special issue belongs to the Section Microbiology)
Sustainable Waste Management: Application of Biotechnology to Reduce Waste
edited by and Hande Ermis
submission deadline 1 Jun 2026 | Viewed by 73 | Submission Open
Keywords: sustainable waste management; environmental biotechnology; microbial waste treatment; bioresource valorization; circular economy; waste-to-energy; bioreactors and bioprocesses; enzymatic degradation; industrial and municipal waste treatment
(This special issue belongs to the Section Biotechnology)
Recent Advances in Biosynthesis and Degradation of Plant Anthocyanin
edited by and
submission deadline 15 Jun 2026 | 8 articles | Viewed by 16962 | Submission Open
Keywords: anthocyanin; fruit ripening; flowering coloration; leaf coloration; secondary metabolite; molecular mechanism
(This special issue belongs to the Section Plant Science)
From Basics to Applications of Gene Regulatory Networks
edited by
submission deadline 15 Jun 2026 | 4 articles | Viewed by 6529 | Submission Open
Keywords: gene regulatory networks; computational methods; modeling and simulation; disease mechanisms; therapeutic targeting; transcriptomics
(This special issue belongs to the Section Genetics and Genomics)
Targeting Neuromuscular Plasticity in Injury and Motoneuron Disease
edited by
submission deadline 15 Jun 2026 | Viewed by 59 | Submission Open
Keywords: neural plasticity; dendritic remodelling; axonal sprouting; metabolic changes; mitochondrial dysfunction; amyotrophic lateral sclerosis; motoneuron; spinal cord injury; regenerative medicine
(This special issue belongs to the Section Neuroscience)
Pregnancy Health and Complications: Molecular Processes and Mechanisms
edited by
submission deadline 30 Jun 2026 | 6 articles | Viewed by 34519 | Submission Open
Keywords: placenta; uterine; fetus; adverse pregnancy outcome; preterm birth; preeclampsia; gestational diabetes; maternal– fetal interface; immune tolerance; inflammation
(This special issue belongs to the Section Developmental and Reproductive Biology)
New Insights into Skeletal Muscle Metabolism in Pathological and Physiological Conditions
edited by
submission deadline 30 Jun 2026 | 10 articles | Viewed by 11430 | Submission Open
Keywords: skeletal muscle; muscle diseases; hormones; physical exercise; muscle physiology; biomarkers; disease prevention; antibodies; pharmacological approaches; cell metabolism
(This special issue belongs to the Section Cell Biology)
Advances in Infection and Genetic Diversity of Zoonotic Parasites, Hosts and Vectors submission deadline 30 Jun 2026 | 1 articles | Viewed by 2162 | Submission Open
Keywords: zoonotic parasites; prevalence of infection; helminths; protozoa; vectors; genetic diversity; zoonoses; hosts
(This special issue belongs to the Section Infection Biology)
Current Advances in Echinoderm Research (2nd Edition)
edited by and
submission deadline 30 Jun 2026 | 3 articles | Viewed by 1982 | Submission Open
Keywords: echinoderms; sea cucumbers; starfish; brittle stars; sea urchins
Advances in Research on Diseases of Plants (2nd Edition)
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1979 | Submission Open
Keywords: phytopathogen; plant immunity; plant disease resistance; gene expression/regulation; signal regulation; pathogenesis; virulence; genetic engineering; disease control
(This special issue belongs to the Section Plant Science)
Plant Stress Physiology: A Trait Perspective
edited by Shuang-Xi Zhou, and Yanchang Wang
submission deadline 30 Jun 2026 | 3 articles | Viewed by 1955 | Submission Open
Keywords: photosynthetic traits; hydraulic traits; metabolic traits; stoichiometric traits; molecular traits; trait plasticity; trait adjustment; stress adaptation; climate resilience
(This special issue belongs to the Section Plant Science)
Evolution, Genetics, and Conservation of Wildlife Respond to Environmental Changes
edited by Jiang Chang and
submission deadline 30 Jun 2026 | 3 articles | Viewed by 1877 | Submission Open
Keywords: environmental change; wildlife; rapid evolution; genetic diversity; conservation genomics; environmental DNA; species distribution models; adaptive evolution; eco-evolutionary dynamics
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Latest Research in Cancer Multi-Omics
edited by Philip Anthony Sutera
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1319 | Submission Open
Keywords: cancer; multi-omics; genomics; transcriptomics; proteomics; metabolomics; radiomics; pathomics; precision medicine; artificial intelligence
(This special issue belongs to the Section Bioinformatics)
Metals in Biology (2nd Edition)
edited by
submission deadline 30 Jun 2026 | Viewed by 1055 | Submission Open
Keywords: metalloenzymes; iron sulfur cluster; mn cluster; photosystem I; photosystem II
Research Advances in Aquatic Omics
edited by , and Haiping Liu
submission deadline 30 Jun 2026 | 1 articles | Viewed by 855 | Submission Open
Keywords: aquatic animals; genomics; transcriptomics; proteomics; metabolomics; genetics; evolutionary biology
(This special issue belongs to the Section Evolutionary Biology)
Vector-Borne Diseases: Host Infection Mechanisms, Immune Response and Epidemiology submission deadline 30 Jun 2026 | Viewed by 821 | Submission Open
Keywords: vector-borne pathogens; host– vector– pathogen interactions; immune response to arthropod-borne infections; vector competence and ecology; one health surveillance; emerging zoonoses; tick-borne diseases; animal vector-borne diseases; veterinary public health
(This special issue belongs to the Section Immunology)
Advances in Biological Breast Cancer Research (2nd Edition)
edited by Anna-Mart Engelbrecht, and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 707 | Submission Open
Keywords: breast cancer; breast tumor; breast cancer cells; animal models; cell death; cancer diagnosis; cancer treatment; biomarkers; cancer microenvironment; carcinogens; estrogen receptor; molecular biology; cell biology
(This special issue belongs to the Section Cancer Biology)
Advancing Crop Nutritional Quality Through Genomic Approaches
edited by Gen Xu
submission deadline 30 Jun 2026 | 1 articles | Viewed by 662 | Submission Open
Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding
(This special issue belongs to the Section Plant Science)
Paper Collection: Understanding Immune Systems
edited by and Jameel M. Inal
submission deadline 30 Jun 2026 | 1 articles | Viewed by 634 | Submission Open
Keywords: immune mechanisms; evolutionary immunology; comparative immunology; innate immunity; adaptive immunity; autoimmunity; chronic inflammation; immune ageing; host– pathogen interactions; vaccinology; regenerative medicine
(This special issue belongs to the Section Immunology)
Biology, Ecology and Management of Invasive Alien Plants (2nd Edition)
edited by and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 575 | Submission Open
Keywords: changes in the composition and distribution of alien plants; invasive mechanisms; invasiveness; invasibility; invasive population; invasive plant interactions with other organisms; impacts on environment; ecosystem services and human health; chemical control; management of invasive plants; utilization of invasive plants
(This special issue belongs to the Section Plant Science)
Precision Nutrition: Unraveling the Molecular Physiology of Nutrient–Gut–Health Axis in Livestock and Poultry
edited by Shengchen Wang, Tingting Li and Xiaoyan Cui
submission deadline 30 Jun 2026 | 1 articles | Viewed by 566 | Submission Open
Keywords: livestock; poultry; animal production; essential nutrients; bioactive compounds; metabolism; animal health; gut physiology; microbiota; molecular
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Interactions Between Membrane Proteins and Membrane Lipids
edited by
submission deadline 30 Jun 2026 | Viewed by 431 | Submission Open
Keywords: membrane protein; lipid bilayer; enzyme; channel; receptor; transporter; cryo-EM; X-ray crystallography; structural biology; drug target
(This special issue belongs to the Section Biophysics)
Mechanisms of Drug Resistance in Cancer Cells
edited by , and
submission deadline 30 Jun 2026 | Viewed by 327 | Submission Open
Keywords: drug resistance; mechanisms; cell growth; cell proliferation; efficacy
(This special issue belongs to the Section Medical Biology)
Genomics and Bioinformatics in Microorganism from the Class Insecta
edited by Irám Pablo Rodríguez-Sánchez
submission deadline 30 Jun 2026 | Viewed by 118 | Submission Open
Keywords: genomics; bioinformatics; microbial communities; insect microbiomes; multi-omics; metagenomics; transcriptomics; host-microbe interactions; evolutionary dynamicsbiotechnological applications
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Nutritional Physiology of Animals
edited by , and Jia Zhou
submission deadline 30 Jun 2026 | Viewed by 111 | Submission Open
Keywords: animals; nutrition; feed additives; novel feed resources; physiology; digestibility; metabolism; stress; reproduction; multi-omics
(This special issue belongs to the Section Physiology)
Genetic Breeding and Reproduction of Aquatic Animals—2nd Edition
edited by , Dongmei Ma and
submission deadline 30 Jun 2026 | Viewed by 108 | Submission Open
Keywords: genetic breeding; reproduction technology; gene; protein; molecular marker; trait; QTLs; molecular marker; fish; shrimp; crab; shellfish; aquatic animals; transcriptomics; proteomics; metabonomics
(This special issue belongs to the Section Zoology)
Applications of Yeast Biotechnology
edited by
submission deadline 30 Jun 2026 | Viewed by 107 | Submission Open
Keywords: biofuel and feed production; biological control; waste treatment and utilization; yeast metabolites; enzyme technology; yeast strain development; process development
(This special issue belongs to the Section Biotechnology)
Breaking Barriers in Metabolic Health: Novel Insights into Obesity and Metabolic Disorders
edited by Aijun Qiao
submission deadline 30 Jun 2026 | Viewed by 90 | Submission Open
Keywords: metabolic disorders; pathogenesis and mechanisms; biomarkers
(This special issue belongs to the Section Medical Biology)
The Plasticity of Autonomic Ganglia submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open
Keywords: acetylcholine; GABA; co-transmission; neuroplasticity; transmitter segregation; synapse; gLTP; binge-eating disorders; dysautonomia; heart disease
(This special issue belongs to the Section Neuroscience)
Cytochrome P450s Across Biological Systems: From Molecular Mechanisms to Biotechnological and Biomedical Applications submission deadline 30 Jun 2026 | Viewed by 81 | Submission Open
Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; biocatalysis and biotransformation; orphan enzymes; redox biology; structural biology; synthetic biology; enzyme engineering; multi-omics approaches
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Environmental and Disease-Driven Biomechanical Stress in Red Blood Cell Biology
edited by
submission deadline 30 Jun 2026 | Viewed by 72 | Submission Open
Keywords: RBCs and environmental factors; RBCs and biomechanical stress; RBCs and pathological conditions; RBCs and microcirculation; RBCs and biomarkers for diseases
(This special issue belongs to the Section Biophysics)
Novel Insights of Bone Repair: Strategies for Improvement, Microscopic, Molecular and Ultrastrastructural Aspects—2nd Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 69 | Submission Open
Keywords: bone repair; aging; bone remodeling; biomaterials; drug delivery; bone regeneration
(This special issue belongs to the Section Medical Biology)
Biosynthesis and Regulation of Plant Tissue-Specific Metabolites
edited by
submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open
Keywords: underground tissue metabolites; root; root exudates; genetic regulation; rhizosphere microbial interaction; environmental response
(This special issue belongs to the Section Plant Science)
Immune Response Regulation in Animals (2nd Edition)
edited by and
submission deadline 30 Jun 2026 | Viewed by 55 | Submission Open
Keywords: immunoregulation of animals; vaccination; immunomodulators; immune memory; cytokine; biotechnology; immune response; molecular networks
(This special issue belongs to the Section Immunology)
The Role of Epigenetics in Cell Fate Determination, Cancer Development, and Aging
edited by and
submission deadline 30 Jun 2026 | Viewed by 29 | Submission Open
Keywords: epigenetics; cell fate determination; cell fate determination; cancer epigenetics; aging; DNA methylation; histone modification; chromatin remodeling; epigenome editing; epigenetic therapy; stem cells
(This special issue belongs to the Section Cell Biology)
Neurogenetics of Behaviour (Volume II) submission deadline 30 Jun 2026 | Viewed by 17 | Submission Open
Keywords: behaviour; genetics; molecules; species; brain; networks; health; disease
(This special issue belongs to the Section Genetics and Genomics)
Research on the Interaction Mechanism Between Animal Intestine and Its Microbiota
edited by and Xiaomin Guo
submission deadline 1 Jul 2026 | Viewed by 234 | Submission Open
Keywords: animal disease; innate immunity; gut microbiota; gut barrier; immune homeostasis
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Feature Papers in 'Conservation Biology and Biodiversity' (2nd Edition)
edited by
submission deadline 1 Jul 2026 | Viewed by 80 | Submission Open
Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Microbial Responses, Pollutant Toxicity Mechanisms, and Human Health Implications
edited by , Zhongquan Jiang and
submission deadline 10 Jul 2026 | 1 articles | Viewed by 718 | Submission Open
Keywords: heavy metal and emerging pollutants; microbiology and plant physiology; aquatic biology; environmental chemistry; anthropogenic disturbances; machine learning; pangenome analysis; computational toxicology; human health
Ultrastructure and Function in In Vitro Cancer Models: From Morphology to Mechanism submission deadline 15 Jul 2026 | Viewed by 16 | Submission Open
Keywords: cancer; organoids; spheroids; transmission electron microscopy; scanning electron microscopy; focused ion beam (FIB)
(This special issue belongs to the Section Cancer Biology)
Plant Perception, Behavior, and Environmental Response Mechanisms
edited by and Bianca Bonato
submission deadline 15 Jul 2026 | Viewed by 9 | Submission Open
Keywords: plant perception; plant movement; social cognition; communication; plant behavior; climbing plants; interactions; plant– plant interactions; environment; plant– environment interactions
(This special issue belongs to the Section Plant Science)
Methods in Bioinformatics and Computational Biology
edited by
submission deadline 25 Jul 2026 | Viewed by 114 | Submission Open
Keywords: bioinformatics; computational biology; machine learning in biomedicine; artificial intelligence; single-cell and spatial transcriptomics analysis; biological network analysis; high-throughput data analysis
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