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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Insights into the Immune Contexture of Tumors

edited by

Leonardo Oliveira Reis

and Guilherme Zweig Rocha

submission deadline 31 Mar 2026 | Viewed by 107 | Submission Open

Keywords: immunology; immune oncology; cancer; molecular biology; biomarkers; inflammation

(This special issue belongs to the Section Cancer Biology)

Signaling Mechanisms Controlling Cell Fate in Cancer

edited by Wittaya Chaiwangyen and

Orawan Khantamat

submission deadline 31 Mar 2026 | Viewed by 58 | Submission Open

Keywords: cell fate; cancer signaling; miRNA; p53; Wnt; apoptosis; proliferation; differentiation; therapy resistance; biomarkers

(This special issue belongs to the Section Cell Biology)

Bird Biology and Conservation

edited by

Alessandro Ferrarini

submission deadline 15 Apr 2026 | 11 articles | Viewed by 13754 | Submission Open

Keywords: avian conservation; ecological modeling; GIS; spatial ecology; telemetry

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Mitochondria: The Signaling Organelle

edited by

Nathan Lanning

submission deadline 15 Apr 2026 | 3 articles | Viewed by 6184 | Submission Open

Keywords: mitochondria; signal transduction; homeostasis; metabolism; apoptosis; redox biology; organelle communication

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Maternal Adaptation in Physiological and Pathological Pregnancy (2nd Edition)

edited by

Qi Chen

and

Yunhui Tang

submission deadline 15 Apr 2026 | Viewed by 126 | Submission Open

Keywords: pregnancy; maternal adaptation; placenta; cardiovascular system; immune system; complications of preg-nancy; early prediction

(This special issue belongs to the Section Developmental and Reproductive Biology)

Microbial Drivers of Aquatic Ecosystem Function: From Genomes to Biogeochemical Cycles

edited by

Ji Li

and Jinjun Kan

submission deadline 15 Apr 2026 | Viewed by 66 | Submission Open

Keywords: aquatic microbial ecology; harmful algal blooms; nutrient cycling; trophic interactions; omics technologies; ecosystem resilience; bioremediation; population dynamics in aquatic ecosystems

(This special issue belongs to the Section Marine Biology)

Biology, Ecology, Management and Conservation of Canidae

edited by Alberto Meriggi and

Francesco Maria Angelici

submission deadline 30 Apr 2026 | 8 articles | Viewed by 15266 | Submission Open

Keywords: Canidae; biology; ecology; management; conservation; ecosystem; habitats; niches; biodiversity; physiology; reproduction

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Zoonotic Diseases

edited by

Francesca Mancianti

and

Valentina Virginia Ebani

submission deadline 30 Apr 2026 | 6 articles | Viewed by 6753 | Submission Open

Keywords: zoonoses; zoonotic agents; bacteria; viruses; fungi; protozoa; helminths

(This special issue belongs to the Section Infection Biology)

Application of Metabolomics and Integrated Computing in Chemical Biology

edited by

Saheed Sabiu

submission deadline 30 Apr 2026 | 2 articles | Viewed by 4381 | Submission Open

Keywords: chemical biology; computational biology; metabolomics; computational modeling; new chemical entities (NCE); active pharmaceutical ingredients (API); characterization; metabolite profiling

Machine Learning Applications in Biology—2nd Edition

edited by

Georgios K. Georgakilas

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3527 | Submission Open

Keywords: machine learning; genomics; epigenomics; genetic variation and the environment; gene regulatory networks; integration of multipurpose NGS data

(This special issue belongs to the Section Bioinformatics)

Advances in Systems Metabolic Engineering for Biochemicals Production

edited by

Huan Liu

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2360 | Submission Open

Keywords: systems metabolic engineering; biochemicals; synthetic biology; bioprocess engineering; pathway modification; strain development

(This special issue belongs to the Section Microbiology)

Advancing Translational Science Using Bioinformatics and Big Data-Driven Approaches

edited by

Zongliang Yue

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2195 | Submission Open

Keywords: bioinformatics; big data analytics; artificial intelligence (AI); machine learning; deep learning; translational science; computational biology; drug repositioning; biomarker discovery; genomics; medical imaging; digital pathology; integrative analysis; disease mechanisms; functional genomics analysis; computational tool application; ethical and safety considerations; data-driven approaches

(This special issue belongs to the Section Bioinformatics)

Recent Advances in Animal Anatomy

edited by

Korakot Nganvongpanit

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2057 | Submission Open

Keywords: animal anatomy; comparative morphology; imaging anatomy; molecular anatomy; veterinary anatomy; functional morphology; evolutionary biology; wildlife conservation; developmental anatomy; anatomical adaptations

(This special issue belongs to the Section Zoology)

Molecular Basis of Seed Germination and Dormancy

edited by

Yifeng Wang

Jiezheng Ying

Xiaohong Tong

and Yu Cheng

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2025 | Submission Open

Keywords: molecular mechanism; genetic basis; seed germination; dormancy; genetic improvement

(This special issue belongs to the Section Plant Science)

Epigenetic and Genetic Control of Sperm Development and Function: From Fertility to Inheritance

edited by

Candela Rocío González

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1145 | Submission Open

Keywords: spermatogenesis; epigenetics; sperm; male fertility; DNA methylation; histone modifications; small RNAs; epigenetic inheritance

(This special issue belongs to the Section Genetics and Genomics)

Natural Compounds Targeting 12 Hallmarks of Aging: A Path to Longevity Intervention

edited by

Tawin Iempridee

and

Wannita Klinngam

submission deadline 30 Apr 2026 | Viewed by 819 | Submission Open

Keywords: natural compounds; antiaging interventions; hallmarks of aging; telomere; epigenetics; autophagy; cellular senescence; pharmaceuticals

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Machine Learning in Pathogen Discovery

edited by

Hong Li

submission deadline 30 Apr 2026 | Viewed by 331 | Submission Open

Keywords: pathogen; machine learning; disease; antibiotic; virulence

(This special issue belongs to the Section Bioinformatics)

Effects of Aquatic Sediments on Marine Ecosystems

edited by Ehui Tan and Sibo Zhang

submission deadline 30 Apr 2026 | Viewed by 315 | Submission Open

Keywords: biogeochemical cycling processes; microbial activity; sediment– water interface; benthic organisms; pollutants; global change; nutrients; environmental issues

(This special issue belongs to the Section Ecology)

The Molecular Mechanisms of Chronic Inflammation Occurrence and Development

edited by Meixiu Jiang

submission deadline 30 Apr 2026 | Viewed by 297 | Submission Open

Keywords: atherosclerosis; vascular calcification; neointima; macrophage; inflammation; phenotypic transformation of smooth muscle cell; endothelial dysfunction

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Advances in Cell and Experimental Biology: Cellular Organelle Stress and Homeostasis in Physiology and Diseases

edited by

Wen-Xing Ding

submission deadline 30 Apr 2026 | Viewed by 146 | Submission Open

Keywords: autophagy; integrated stress response; proteotoxic stress response; organelle homeostasis; ubiquitination

(This special issue belongs to the Section Cell Biology)

Germplasm Resources and Molecular Breeding for Sustainable Aquatic Species Improvement

edited by Falin Zhou

submission deadline 30 Apr 2026 | Viewed by 141 | Submission Open

Keywords: germplasm resource evaluation; molecular marker; genomics; gene editing; selective breeding; environment adaptation

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Progress in Microbial Genetics and Genomics

edited by

Rapee Thummeepak

and Udomluk Leungtongkam

submission deadline 30 Apr 2026 | Viewed by 126 | Submission Open

Keywords: antimicrobial resistance (AMR); microbial genetics and genomics; high-throughput DNA sequencing; comparative genomics and pan-genome; metagenomics and microbiome; mobilome; resistome and virulome; medical microbiology; environmental and food microbiology; probiotic genomics; bacteriology; mycology and virology

(This special issue belongs to the Section Microbiology)

Natural Compound–Drug Interactions Related to Metabolizing Enzymes and Transporters

edited by

Mei Hong

submission deadline 30 Apr 2026 | Viewed by 112 | Submission Open

Keywords: drug transporters; drug-metabolizing enzymes; natural products; herb– drug interactions; food– drug interactions; nuclear receptors; kinases; expression regulation; protein targeting; functional regulation

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Animal Models for Disease Mechanisms (2nd Edition)

edited by

Isabel R. Dias

submission deadline 30 Apr 2026 | Viewed by 107 | Submission Open

Keywords: animal models; spontaneous models; induced models; disease mechanisms; pathogenesis research

(This special issue belongs to the Section Zoology)

Cutting-Edge Biomechanics: Unlocking the Future of Biomedical Engineering

edited by

Ye Zeng

submission deadline 30 Apr 2026 | Viewed by 96 | Submission Open

Keywords: computational biomechanics; experimental biomechanics; cellular and molecular biomechanics; tissue biomechanics and regenerative engineering; cardiovascular biomechanics; musculoskeletal biomechanics; sports and injury biomechanics; biomaterials and medical device innovation; medical robotics and haptics; AI and machine learning in biomechanics

(This special issue belongs to the Section Biophysics)

Advances in Cell Division and Chromosome Segregation Mechanisms

edited by Zhixin (Jason) Lyu

submission deadline 30 Apr 2026 | Viewed by 40 | Submission Open

Keywords: cell division; chromosome segregation; bacterial cell biology; mammalian cell cycle; genome stability; cytoskeletal dynamics; structural biology; advanced imaging

(This special issue belongs to the Section Cell Biology)

The Impact of Climate Change on Quality, Yield, and Nutritional Properties of Cereals, Legumes, and Oilseeds

edited by

Vito Butardo

submission deadline 1 May 2026 | 1 articles | Viewed by 1823 | Submission Open

Keywords: climate change; cereals; legumes; oilseeds; grain quality; seed nutrition; yield; elevated temperatures; drought; salinity; atmospheric CO2; multi-omics; field trials; crop modelling; data integration; climate resilience; breed-ing strategies; agronomic practices; beneficial microorganisms; underutilised crops; orphan crops

(This special issue belongs to the Section Plant Science)

Microbial Contamination and Food Safety (Volume II)

edited by

Joana Barbosa

submission deadline 15 May 2026 | 5 articles | Viewed by 15338 | Submission Open

Keywords: food contamination; food safety practices; microbial inactivation; microbial safety; microbiological hazards

(This special issue belongs to the Section Microbiology)

Internal Defense System and Evolution of Aquatic Animals

edited by

Alessio Alesci

submission deadline 15 May 2026 | 8 articles | Viewed by 13516 | Submission Open

Keywords: internal defense system; evolution; aquatic animals; immunology; aquatic environment; biodiversity; pollution; ecosystems

(This special issue belongs to the Section Evolutionary Biology)

Genetic and Genomic Insights into Cardiovascular Disease

edited by Silvio Zaina and

Carol C. Shoulders

submission deadline 15 May 2026 | Viewed by 113 | Submission Open

Keywords: coronary and carotid atheroma; lipids; thrombosis; inflammation; vascular calcification; vascular smooth muscle cells; foam cells; endothelium; immune cells; epigenetics; genetic variation; gene expression and proteomics; cell and disease models

(This special issue belongs to the Section Genetics and Genomics)

The Biology of Animal Reproduction

edited by

Jingli Tao

submission deadline 30 May 2026 | 9 articles | Viewed by 11580 | Submission Open

Keywords: the regulation of animal reproduction; follicular development and atresia; gamete and embryo development; hormonal control of reproductive processes; epigenetic regulation in reproductive biology

(This special issue belongs to the Section Developmental and Reproductive Biology)

Genetic Variability within and between Populations

edited by

Sankar Subramanian

submission deadline 31 May 2026 | 15 articles | Viewed by 13010 | Submission Open

Keywords: genetic structure; population differentiation; FST or fixation index; migration; gene flow; admixture; heterozygosity; inbreeding; coalescence time; allele frequency; random mating

(This special issue belongs to the Section Evolutionary Biology)

Aquatic Animal Nutrition and Feed

edited by

Yun Wang

submission deadline 31 May 2026 | 8 articles | Viewed by 9484 | Submission Open

Keywords: aquaculture; aquatic animals; nutrition; aquatic feed; immunity; metabolism

Application of Bioinformatics to Unravel the Molecular Mechanisms of Cancer Biology

edited by

Yuanyan Xiong

submission deadline 31 May 2026 | 5 articles | Viewed by 9225 | Submission Open

Keywords: cancer biology; bioinformatics; genetics; epigenetics; transcriptomics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Stem Cells in Experimental Medicine

edited by Xinhua Liao and

Xusheng Wang

submission deadline 31 May 2026 | 1 articles | Viewed by 8018 | Submission Open

Keywords: adult stem cells; induced pluripotent stem cells (iPSs); embryonic stem cells; progenitor cells; stem-cell-derived organoids; stem-cell-derived exosomes; stem-cell-based therapy; stem-cell-based disease modeling; stem-cell-based tissue engineering

(This special issue belongs to the Section Cell Biology)

Artificial Intelligence Research for Complex Biological Systems

edited by

Yong Chen

and

Milana Frenkel-Morgenstern

submission deadline 31 May 2026 | 6 articles | Viewed by 7634 | Submission Open

Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics

(This special issue belongs to the Section Bioinformatics)

Young Researchers in Conservation Biology and Biodiversity

edited by

Ettore Randi

submission deadline 31 May 2026 | 4 articles | Viewed by 4230 | Submission Open

Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Mechanisms Underlying Neuronal Network Activity

edited by Jorge Flores-Hernandez

submission deadline 31 May 2026 | 2 articles | Viewed by 3485 | Submission Open

Keywords: neurons; brain circuits; NMDA receptors; acetylcholine; excitability; Parkinson’ s; schizophrenia; learning; attention

(This special issue belongs to the Section Neuroscience)

Research Progress on Salt Stress in Plants

edited by

Yan Cheng

submission deadline 31 May 2026 | 3 articles | Viewed by 2414 | Submission Open

Keywords: salt stress; plants; crops; soil salinization; salt tolerance; abiotic stress; plant protection; plant breeding

(This special issue belongs to the Section Plant Science)

The Biology and Behavior of Bees

edited by

Dimitrios Kanelis

submission deadline 31 May 2026 | 1 articles | Viewed by 2139 | Submission Open

Keywords: pollinators; bee anatomy; bee foraging behavior; bee communication; bee social structure; environmental stressors of bees; effect of pesticide on bees’ behavior; bees’ habitat loss; natural enemies of bees; bees’ disease management

(This special issue belongs to the Section Zoology)

Impact of Climate Change on Structural and Functional Characteristics of Freshwater Ecosystems and Its Implications for Their Resources’ Management

edited by

Franca Sangiorgio

and

Maurizio Pinna

submission deadline 31 May 2026 | 1 articles | Viewed by 1981 | Submission Open

Keywords: AI applications; biodiversity; biological assemblages; climate change; ecological resilience; ecosystem ser-vices; freshwater ecosystems; nutrient cycling; temperature

(This special issue belongs to the Section Ecology)

New Insights in Cancer Genetics—2nd Edition

edited by

Ilda Patrícia Ribeiro

, Isabel Marques Carreira and

Alberto Orfao

submission deadline 31 May 2026 | 1 articles | Viewed by 1886 | Submission Open

Keywords: genomic and epigenetic characterization; diagnosis and prognosis biomarkers; omics profiles; genetic and genomic signature; molecular heterogeneity; molecular targeted therapy; oncogenic signaling pathways; copy number alterations and mutational landscape; chromosome abnormalities

(This special issue belongs to the Section Cancer Biology)

Recent Advances in Metabolic Disorders

edited by

Vinood B. Patel

submission deadline 31 May 2026 | 1 articles | Viewed by 1505 | Submission Open

Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals; alcohol; treatment TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Physiology)

The Role of Lipids in Cardiovascular and Neurodegenerative Diseases

edited by

Yuanyuan Ji

Ronghui Gu

and Yaxin Li

submission deadline 31 May 2026 | 1 articles | Viewed by 1231 | Submission Open

Keywords: lipid biology; lipid peroxidation; lipidomics; lipid foods or nutrients; cardiovascular disease; neurodegenerative diseases

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Recent Advances in Biological Research on Prostate Cancer

edited by Samson Mashele and Pakiso Makhoahle

submission deadline 31 May 2026 | 1 articles | Viewed by 1192 | Submission Open

Keywords: prostate cancer; biological research; molecular mechanisms; biomarkers; precision medicine; therapeutic targets; tumor microenvironment; therapeutic resistance; genomics; quality of life

(This special issue belongs to the Section Cancer Biology)

Head and Neck Cancer: Current Advances and Future Perspectives

edited by Ana Jotic

submission deadline 31 May 2026 | 1 articles | Viewed by 779 | Submission Open

Keywords: head and neck cancer; tumor microenvironment; genetic and epigenetic alterations; oncogenes and tumor suppressor genes; signal transduction pathways; immune evasion; metastasis; drug resistance mechanisms; molecular etiology; cancer biology

(This special issue belongs to the Section Cancer Biology)

Understanding and Targeting Biological Mechanisms of Heart Failure (2nd Edition)

edited by

Lei Ye

and

Wuqiang Zhu

submission deadline 31 May 2026 | Viewed by 673 | Submission Open

Keywords: developmental biology; genetics; stem cells; heart failure; cell therapy

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Coping with Temperature Increase Induced by Climate Warming: Trends in Ectothermic Species—2nd Edition

edited by

Andreas Walzer

submission deadline 31 May 2026 | 1 articles | Viewed by 655 | Submission Open

Keywords: biodiversity; climate warming; ectothermic species; geographic ranges; heat waves; evolutionary adaptations; phenotypic plasticity; species interactions; thermal acclimation

Molecular and Neurological Aspects of Sensory Processing Disorders

edited by

Laura Clara Grandi

Daniele Corbo

and

Stefania Bruni

submission deadline 31 May 2026 | Viewed by 506 | Submission Open

Keywords: sensory processing; sensory processing disorders; SPDs; sensory stimuli; brain activity; genetic; functional neuroimaging studies

(This special issue belongs to the Section Neuroscience)

Studies on Antioxidant Activity of Natural Products from Plants

edited by

Pornsiri Pitchakarn

and

Piya Temviriyanukul

submission deadline 31 May 2026 | Viewed by 374 | Submission Open

Keywords: plant natural products; phytochemicals; antioxidant activity; free radical scavenging; functional foods; oxidative stress-accelerated diseases

(This special issue belongs to the Section Plant Science)

Displaying special issue 151-200 on page 4 of 7.

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