Genetic Mechanisms in Archaea

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Microbiology".

Deadline for manuscript submissions: 1 May 2024 | Viewed by 250

Special Issue Editors

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Guest Editor
State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
Interests: chromosomal DNA organization; DNA replication; post-translational modification; archaeal virus–host interactions; Sulfolobus cell cycle regulation
Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
Interests: archaeal genetics and genomics; archaeal virus; archaeal cell biology; CRISPR-Cas

Special Issue Information

Dear Colleagues,

DNA transactions on highly organized genomic DNA are an essential cellular process for all living organisms. Archaea employ DNA processing machineries resembling those found in eukaryotes in both structure and function. Owing to the fact that the archaeal proteins/enzymes in these machineries are commonly simpler versions of their counterparts in eukaryotes, archaeal organisms have been regarded as simple prokaryotic model systems that can be used to explore the genetic mechanisms of eukaryotes. On the other hand, many archaeal species have evolved unique proteins or enzymes that serve distinctive roles in chromosome organization and DNA transactions. Therefore, archaea have attracted attention from scientists in the areas of structural biology, biochemistry and genetics.

Although great achievements in this research field have been made, efforts should be made to further understand the genetic mechanisms of archaea at the molecular level. The current Special Issue welcomes both original research and review articles on topics including, but not limited to, the following aspects:

(1) Dynamic of chromosome structure in archaea;

(2) Structure and function of multicomponent molecular machineries in DNA transactions;

(3) Mechanisms of transcription regulation;

(4) Regulating roles of protein post-translational modifications in chromosome structure and gene expression;

(5) DNA replication and integration of archaeal viruses;

(6) New players in regulating the archaeal cell cycle;

(7) Advanced techniques for studying DNA transactions.

Dr. Zhenfeng Zhang
Dr. Changyi Zhang
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • archaea
  • extrachromosomal genetic elements
  • chromosome structure
  • DNA replication
  • DNA repair
  • DNA recombination
  • transcription regulation
  • epigenetic regulation

Published Papers

This special issue is now open for submission.
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