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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biofabrication Technologies: Novel Tools for More Effective Personalized Medicine and Regenerative Therapies

edited by

Giovanni Vozzi

Paola Nieri

and Mauro Di Stasi

submission deadline 31 Jul 2026 | 3 articles | Viewed by 5328 | Submission Open

Keywords: biodegradable polymers; biocompatible polymers; biomedical applications; biomaterials; renewable biomaterials; tissue engineering; regenerative medicine; biofabrication and bioprinting; personalized medicine; 3D tissue models

(This special issue belongs to the Section Regenerative Engineering)

Artificial Intelligence in Neurodegenerative Disorders: Advances in Diagnosis, Prognosis and Treatment

edited by Shayne Chau and Mohd. Farooq Shaikh

submission deadline 31 Jul 2026 | 1 articles | Viewed by 5174 | Submission Open

Keywords: artificial intelligence; neurodegenerative disorders; machine learning in neurology; diagnosis; treatment; prognosis

(This special issue belongs to the Section Biosignal Processing)

Novel Techniques in Meniscus Repair

edited by

Yuya Kodama

and

Yuki Okazaki

submission deadline 31 Jul 2026 | 4 articles | Viewed by 5131 | Submission Open

Keywords: meniscus repair; arthroscopic surgery; meniscal root tear; biologic augmentation; knee joint preservation; meniscal healing; sports medicine; regenerative orthopedics

(This special issue belongs to the Section Regenerative Engineering)

Data Modeling and Algorithms in Biomedical Applications

edited by

Ivan Ganchev Ivanov

submission deadline 31 Jul 2026 | 4 articles | Viewed by 4936 | Submission Open

Keywords: computer models; algorithms; biomedical applications; predictive modeling; machine learning; data analysis; data modeling; AI applications

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Technologies for Spine Research

edited by Hyoungmin Kim

submission deadline 31 Jul 2026 | 4 articles | Viewed by 4200 | Submission Open

Keywords: spine biomechanics; spinal implants and devices; computational modeling; tissue engineering; biomedical imaging; artificial intelligence; motion analysis; surgical robotics; regenerative medicine; predictive modeling; personalized spine care; translational bioengineering; smart materials; image-guided interventions

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Brain Stimulation Technology

edited by

Paolo Belardinelli

and

Giulia Liberati

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4140 | Submission Open

Keywords: brain stimulation; state-dependent brain stimulation; brain disorders; deep brain stimulation; transcranial magnetic stimulation; transcranial electrical stimulation; temporal interference stimulation

(This special issue belongs to the Section Biosignal Processing)

Advancements in Artificial Intelligence for Wearable Devices: A New Perspective on Healthcare Applications—2nd Edition

edited by

Maria Giovanna Bianco

Syed Kamrul Islam

and

Salvatore Andrea Pullano

submission deadline 31 Jul 2026 | 4 articles | Viewed by 3925 | Submission Open

Keywords: wearable devices; artificial ilntelligence; machine learning; biomedical signal processing; deep learning; bio-inspired systems; biosensor devices

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Machine Learning and Explainable Artificial Intelligence in Biomedical Data Mining, and Disease Diagnosis Frameworks—2nd Edition

edited by

Amad Zafar

submission deadline 31 Jul 2026 | 6 articles | Viewed by 3741 | Submission Open

Keywords: EEG; fNIRS; MRI; X-rays; biomedical signal and image processing; machine learning; explainable artificial intelligence; biomedical data mining; computer-aided diagnosis; brain– computer interfaces; healthcare

(This special issue belongs to the Section Biosignal Processing)

Metabolic MRI and Beyond: Emerging Technologies and Translational Biomedical Applications

edited by Kejia Cai and Mohan Jayatilake

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3454 | Submission Open

Keywords: metabolic MRI; CEST MRI; deuterium metabolic imaging; hyperpolarized 13C MRI; Arterial Spin Labeling (ASL); artificial intelligence in MRI; MR spectroscopy

(This special issue belongs to the Section Biosignal Processing)

Printable Biomaterials from Tissue Engineering to Orthopedics: Fabrication, Mechanical Performance, and Biological Behavior

edited by

Gianpaolo Serino

and

Gulden Camci-Unal

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3397 | Submission Open

Keywords: advanced printable biomaterials; biocompatibility; bioactivity; mechanical properties; physical and chemical properties

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Dental Pulp Stem Cells in Clinical Application: Present and Future Perspectives

edited by

Ciro Gargiulo Isacco

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3362 | Submission Open

Keywords: dental pulp stem cells; cell injections; modified cells; cell sheets; cell spheroids; regeneration; damaged tissues; immunomodulation

(This special issue belongs to the Section Regenerative Engineering)

Dental Biomaterials: Current and Future Perspectives

edited by Sandro Basso Bitencourt,

Emily Vivianne Freitas da Silva

and Natalia Bastos-Bitencourt

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3301 | Submission Open

Keywords: dental materials; 3D printing; ceramics; CAD/CAM; bioactivity

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanical Assessment in Rehabilitation and Performance

edited by

Eleftherios Paraskevopoulos

and

Dimitris G. Mandalidis

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2534 | Submission Open

Keywords: motion capture analysis; postural control assessment; gait analysis; wearable sensor technologies; muscle activation studies; joint kinematics; sports injuries; sports therapy

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Engineering with Nature: Bioengineering Innovations for the Environment and Nature-Based Solutions

edited by

Kristian L. Dubrawski

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2286 | Submission Open

Keywords: nature-based solutions; bioengineering; environmental sustainability; bioremediation; ecological engineering

(This special issue belongs to the Section Biochemical Engineering)

Radiation Imaging and Therapy for Biomedical Engineering

edited by Bharat Guthikonda and Stanley Hoang

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2258 | Submission Open

Keywords: radiation imaging; radiation therapy; biomedical engineering; diagnostic technologies; therapeutic innovations

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Next-Generation Biosignal Engineering: AI-Driven Diagnostics, Prosthetic Interfaces and Multimodal Physiological Sensing

edited by

Ejay Nsugbe

and

Luca Mesin

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2199 | Submission Open

Keywords: AI-driven diagnostics; multimodal biosignal processing; wearable and implantable sensors; prosthetic and rehabilitation interfaces; sparse-signal and low-density learning (LSDL-aligned); biomedical machine learning; physiological sensing and monitoring; translational bioengineering; computational neuro-musculoskeletal assessment; personalized and population-health technologies

(This special issue belongs to the Section Biosignal Processing)

New Sights of AI Tools and Deep Learning in Biomedicine

edited by

Mirpouya Mirmozaffari

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1756 | Submission Open

Keywords: artificial intelligence; machine learning; optimization; healthcare management; operation research; biomedicine

(This special issue belongs to the Section Biosignal Processing)

Emerging Artificial Intelligence Trends for Predictive Analytics and Personalized Healthcare

edited by

Josu Maiora

Maria Begoña Sanz Echevarría

and

Manuel Graña

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1748 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; predictive analytics; wearable sensors; medical devices; medical image analysis

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Cardiothoracic Assist Devices

edited by Suvitesh Luthra and

Enrique Berjano

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1746 | Submission Open

Keywords: mechanical circulatory support; VAD; OCS; LBE and EVLP; total artificial heart; heart failure; maglev and axial flow pumps; minimally invasive; wireless power; biocompatibility; AI in cardiac devices

(This special issue belongs to the Section Regenerative Engineering)

Advances in Biomolecular Engineering for Regenerative Therapeutics

edited by

Christopher Robinson

, Paul Jordan Christo and

Matthew Chung

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1578 | Submission Open

Keywords: regenerative medicine; growth factors; gene therapy; exosomes; extracellular vesicles; proteomics; genomics; CRISPR; stem cells

(This special issue belongs to the Section Regenerative Engineering)

Intelligent Healthcare and Auditory Health: Machine Learning-Based Multimodal Biomedical Data Mining for Diagnosis

edited by

Meihong Wu

and

Yunfeng Wu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1481 | Submission Open

Keywords: computer-aided diagnosis; speech signal processing; auditory information processing; neurodegenerative diseases; wearable devices; health informatics; multimodal fusion; telemedicine; rehabilitation engineering; noise-robust algorithms; acoustic feature extraction; cognitive impairment screening; end-to-end speech enhancement

(This special issue belongs to the Section Biosignal Processing)

Gene Delivery for Cancer Therapy

edited by Huiyi Liang and Tianqi Nie

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1418 | Submission Open

Keywords: gene delivery; drug delivery; nanoparticles; hydrogel; cancer

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Biomedical Materials Expansion in Tissue Regeneration: Material and Tissue Evaluation

edited by

Osamu Yamamoto

and Takahiro Kawai

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1345 | Submission Open

Keywords: polymers; metals; gels; collagen; in vivo/in vitro evaluation; cells; animal model; clinical trial; biological tissue regeneration

(This special issue belongs to the Section Regenerative Engineering)

Motor Control Techniques: Integrating Motor Neuroscience and Applied Mathematics

edited by

Osmar Pinto Neto

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1228 | Submission Open

Keywords: motor control; computational neuroscience; neural oscillations; electromyography (EMG); neuromodulation (tDCS; TMS); Bayesian models; motor learning and adaptation; biomechanics; rehabilitation engineering; Parkinson's disease

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Cardiac Digital Twins and AI: From Multi-Modal Modeling to Medical Implementation

edited by Lei Li,

Rodrigo Weber Dos Santos

and Julia Camps

submission deadline 31 Jul 2026 | Viewed by 630 | Submission Open

Keywords: cardiac digital twins; multi-modal modeling; AI in cardiology; clinical translation; multi-modal data integration; personalized cardiac modeling; real-time simulation; cardiovascular precision medicine

(This special issue belongs to the Section Biosignal Processing)

Bioactive Ceramics in Regenerative Medicine: From Bone Grafts to Dental Implants

edited by Wenfan Chen

submission deadline 31 Jul 2026 | Viewed by 502 | Submission Open

Keywords: bioceramics; dental implants; bone grafts; regenerative medicine; bone regeneration; biomaterials; three-dimensional printing

(This special issue belongs to the Section Regenerative Engineering)

Robotics and Virtual Reality for Rehabilitation

edited by

Marcos José Navarro-Santana

submission deadline 31 Jul 2026 | Viewed by 495 | Submission Open

Keywords: rehabilitation technology; wearable robotics; telerehabilitation; virtual reality; artificial intelligence; personalized therapy

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Precision Orthodontics in the Digital Era: From Digital Diagnostics to Personalized Planning and Therapies

edited by

Sinan Şen

and Benedict Wilmes

submission deadline 31 Jul 2026 | Viewed by 425 | Submission Open

Keywords: digital orthodontics; 3D imaging; intraoral scanning; CAD/CAM; interdisciplinary treatment; dysgnathia; CAD/CAM

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Next-Generation Medical Signal and Image Analysis

edited by

Ahmed Elnakib

and Mohamed Shehata

submission deadline 31 Jul 2026 | Viewed by 419 | Submission Open

Keywords: medical signal processing; medical image analysis; EEG; ECG; and EMG analysis; physiological signal processing; artificial intelligence in healthcare; machine learning; deep learning; transformer models; large language models in healthcare; multimodal data analysis; computer-aided diagnosis; big data in healthcare; wearable and sensor-based systems; explainable artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Emerging Applications and Insights for Life and Biomaterial Sciences Through Correlated Volume and Electron Microscopy Advances

edited by

Eduardo Rosa-Molinar

and Mark Sanders

submission deadline 31 Jul 2026 | Viewed by 362 | Submission Open

Keywords: resin electron microscopy; volume electron microscopy; correlated electron microscopy; in situ electron microscopy; analytical electron microscopy; correlated cryo-electron tomography

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

MRI Techniques for Disease Detection

edited by Christine Fernandez-Maloigne

submission deadline 31 Jul 2026 | Viewed by 332 | Submission Open

Keywords: MRI; disease detection; artificial intelligence; deep learning

(This special issue belongs to the Section Biosignal Processing)

Engineering Stem Cells and Their Derivatives for Wound Healing and Tissue Regeneration

edited by Yueh Hsun Kevin Yang

submission deadline 31 Jul 2026 | Viewed by 324 | Submission Open

Keywords: stem cells; extracellular vesicles; biomaterials; immunoengineering; gene editing; regenerative medicine; wound healing

(This special issue belongs to the Section Regenerative Engineering)

Dynamic Insights: Unveiling the Biomechanics of Sport Through Motion Analysis, 2nd Edition

edited by

Ukadike Chris Ugbolue

submission deadline 31 Jul 2026 | Viewed by 289 | Submission Open

Keywords: artificial intelligence; augmented reality; biomechanics; E-sports; instrumentation; kinesiology; machine learning; motion analysis; performance enhancement; virtual reality; wearable technology

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advances in Functional Brain Research Using Multimodal and Integrative Techniques

edited by

Stefania Coelli

, Eleonora Maggioni, Letizia Squarcina and

Augusto Bonilauri

submission deadline 31 Jul 2026 | Viewed by 285 | Submission Open

Keywords: EEG; MEG; fMRI; fNIRS; SEEG; Multimodal imaging; data integration; physiological parameters

(This special issue belongs to the Section Biosignal Processing)

Advancements in Drug Design and Delivery for Neuropsychological Disorders: Integrating Bioinformatics and Nanotechnology

edited by

Tahmineh Mokhtari

submission deadline 31 Jul 2026 | Viewed by 284 | Submission Open

Keywords: neuropsychological disorders; drug design; drug delivery; bioinformatics; nanotechnology; computational drug design; targeted therapies; neuropharmacology; nanomedicine; bioengineering

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Integrative Synthetic Biology and Bioelectronic Sensing: Engineering Biomolecules, Microbial Systems and Intelligent Diagnostic Platforms

edited by

Bruna Matturro

and George Luka

submission deadline 31 Jul 2026 | Viewed by 230 | Submission Open

Keywords: synthetic biology; codon optimization; transformer models; protein engineering; biosensing; electrochemical sensors; bioelectronics; genetic circuit design; computational biology; AI for gene design

(This special issue belongs to the Section Biochemical Engineering)

Medical Image Processing: Emerging Techniques and Future Avenues

edited by

Domenico Buongiorno

, Vittoria Nardone and Aydin Eresen

submission deadline 31 Jul 2026 | Viewed by 201 | Submission Open

Keywords: medical image processing; synthetic data generation; multimodal imaging; artificial intelligence; machine learning; data fusion; explainable AI; clinical applications

(This special issue belongs to the Section Biosignal Processing)

Acute Cartilage and Meniscus Injuries: Treatment Strategies for Repair, Replacement, and Regeneration

edited by Tony Chen and Claire D. Eliasberg

submission deadline 31 Jul 2026 | Viewed by 189 | Submission Open

Keywords: acute cartilage and meniscus injuries; meniscus repair; cartilage healing; scaffolds; implants; orthobiologics

(This special issue belongs to the Section Regenerative Engineering)

Heterologous Microbial Production of Health-Promoting Natural Products

edited by Yuheng Lin

submission deadline 31 Jul 2026 | Viewed by 178 | Submission Open

Keywords: microbial production; heterologous host; metabolic pathway engineering; natural products; health-promoting benefits

(This special issue belongs to the Section Biochemical Engineering)

Advances in Biomaterials and Evaluation for Orthopaedic Implants

edited by Amir Human Hoveidaei and Sean A. Tabaie

submission deadline 1 Aug 2026 | 1 articles | Viewed by 448 | Submission Open

Keywords: orthopaedic implants; biomaterials; osseointegration; surface modification; additive manufacturing; implant evaluation; imaging compatibility

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Methods and Applications of MRI, fNIRS, and EEG

edited by

Dongrong Xu

Ravi Bansal

and

Weihui Dai

submission deadline 25 Aug 2026 | 1 articles | Viewed by 2382 | Submission Open

Keywords: MRI; multiparametric MRI; cancer Imaging; tumor characterization; therapy monitoring; whole-body MRI; pediatric MRI; oncologic imaging; clinical MRI

(This special issue belongs to the Section Biosignal Processing)

Advanced Cryopreservation and Innovative Rewarming Strategies for Cells, Tissues, Organs and Organisms

edited by

Ramon Risco

and

Estefanía Paredes

submission deadline 25 Aug 2026 | Viewed by 459 | Submission Open

Keywords: cryopreservation; vitrification strategies; rewarming technologies; cryoprotective agents; fertility preservation; plant cryobiology; aquatic species conservation; astrobiology and extreme environments

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Novel Biotechnology and Tissue Engineering Approaches for Muscle Repair

edited by

Michael J. Mcclure

submission deadline 30 Aug 2026 | Viewed by 169 | Submission Open

Keywords: skeletal muscle; nerve; neuromuscular junction; motor endplate; muscle function

(This special issue belongs to the Section Regenerative Engineering)

Musculoskeletal Function in Health and Disease

edited by Adrian Paul Harrison and Else Marie Bartels

submission deadline 31 Aug 2026 | 7 articles | Viewed by 23231 | Submission Open

Keywords: musculoskeletal disorders; muscle injury; pre-habilitation and rehabilitation; healthcare; wearable technology; quality of life; sport science; sport medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence-Based Medical Imaging Processing

edited by Xin Meng and Yuxiang Zhou

submission deadline 31 Aug 2026 | 14 articles | Viewed by 23158 | Submission Open

Keywords: artificial intelligence; medical imaging; disease detection and prediction; quantitative analysis; clinical integration; bias resilience; model transparency; precision medicine

(This special issue belongs to the Section Biosignal Processing)

Bioengineering and the Eye—3rd Edition

edited by

Dimitrios Karamichos

submission deadline 31 Aug 2026 | 12 articles | Viewed by 16551 | Submission Open

Keywords: stem cell therapies; functional ocular tissue equivalents; biomaterials; 3D bioprinting; tissue engineering

(This special issue belongs to the Section Regenerative Engineering)

AI Advancements in Healthcare: Medical Imaging and Sensing Technologies, 2nd Edition

edited by

Mohammed A. Al-masni

and Kanghyun Ryu

submission deadline 31 Aug 2026 | 10 articles | Viewed by 15109 | Submission Open

Keywords: biomedical imaging; biosignals; medical image analysis; abnormalities classification and detection; medical image segmentation; medical image reconstruction; medical image denoising; medical image registration; AI in biomedical systems; computer-aided diagnosis systems

(This special issue belongs to the Section Biosignal Processing)

Bioengineering in a Generative AI World

edited by

Yifan Zhao

, Ulas Bagci and Yuxiang Zhou

submission deadline 31 Aug 2026 | 4 articles | Viewed by 12252 | Submission Open

Keywords: generative AI; bioengineering; machine learning; synthetic biology; drug discovery

(This special issue belongs to the Section Biosignal Processing)

AI and Data Analysis in Neurological Disease Management

edited by

Bess Lam

and

Ka-Chun Wong

submission deadline 31 Aug 2026 | 8 articles | Viewed by 9200 | Submission Open

Keywords: AI technologies; management of neurological diseases; interdisciplinary approaches; data analysis

(This special issue belongs to the Section Biosignal Processing)

Advanced 3D-Printed Biomaterials in Dentistry

edited by Andreas Zenthöfer and Ralf Erber

submission deadline 31 Aug 2026 | 5 articles | Viewed by 7986 | Submission Open

Keywords: additive manufacturing; 3D printing; ceramics; polymer-based materials; bone substitutes

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

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