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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Developments in Drug Delivery Systems

edited by

Ching-An Peng

submission deadline 31 Aug 2025 | Viewed by 85 | Submission Open

Keywords: drug delivery systems; nanomedicine; controlled release; stimulus-responsive materials; gene delivery; biocompatible polymers; precision medicine; implantable devices; bioinspired delivery; artificial intelligence in drug delivery

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Neuromorphic Computing in Bioengineering Applications

edited by William C. Tang and Nathan Leroux

submission deadline 15 Sep 2025 | Viewed by 112 | Submission Open

Keywords: neuromorphic computing; bioengineering; hardware design and architectures; algorithms and models; AI; machine learning; neuromorphic sensors; neuromorphic interfaces; energy-efficient systems; neural network models; computational neuroscience

(This special issue belongs to the Section Biosignal Processing)

Advancements and Innovations in Photoacoustic Imaging: Pioneering Techniques and Clinical Applications in Biomedical Research

edited by

Praveen Kumar Panangattukara Prabhakaran

Taeho Kim

and

Dong-Kwon Lim

submission deadline 15 Sep 2025 | Viewed by 107 | Submission Open

Keywords: tomography; deep tissue imaging; photoacoustic imaging; contrast agents; probes; nanoparticles; clinical applications; multimode imaging

(This special issue belongs to the Section Biosignal Processing)

Advancements in Bioelectronics: From Beaker to Wearable to Implantable Devices

edited by

Aneesh Koyappayil

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3830 | Submission Open

Keywords: wearable biosensors; flexible and stretchable electronics; bioelectronic devices; implantable electronics; "more than moore" electronics; individualized healthcare

(This special issue belongs to the Section Biosignal Processing)

Vascular Interventions and Their Techniques

edited by Elias Kehayas

submission deadline 20 Sep 2025 | 1 articles | Viewed by 730 | Submission Open

Keywords: vascular interventions; vascular procedures; vascular surgery; endovascular techniques; minimally invasive vascular procedures; interventional radiology; angioplasty; stenting; embolization; thrombolysis; atherectomy; intravascular lithoplasty; thrombectomy; vascular access techniques; catheterization; vascular imaging; vascular interventions for peripheral artery disease

(This special issue belongs to the Section Regenerative Engineering)

Recent Advances in Soft Tissue Characterization Using Optical Techniques

edited by Bin Yang,

John Viator

and Xu Feng

submission deadline 20 Sep 2025 | 1 articles | Viewed by 188 | Submission Open

Keywords: optical elastography; spectroscopy; optical imaging; disease diagnostics; tissue optics; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Neuromorphic and Bioinspired Computing: Bridging Biology and Technology

edited by

Arash Ahmadi

and Amirali Amirsoleimani

submission deadline 25 Sep 2025 | Viewed by 601 | Submission Open

Keywords: neuromorphic; bioinspired computing; biological systems; brain; neural networks; machine learning; artificial intelligence; algorithms

(This special issue belongs to the Section Biosignal Processing)

AI in OCT (Optical Coherence Tomography) Image Analysis

edited by

Juhwan Lee

and Kiran Kumar Vupparaboina

submission deadline 30 Sep 2025 | 7 articles | Viewed by 12377 | Submission Open

Keywords: retinal imaging; dental imaging; intravascular imaging; optical coherence tomography; machine learning; deep learning; advanced image processing

(This special issue belongs to the Section Biosignal Processing)

Computational Models in Cardiovascular System

edited by Ghassan S. Kassab

submission deadline 30 Sep 2025 | 9 articles | Viewed by 11527 | Submission Open

Keywords: biomechanics; heart; vessels; finite element analysis; artificial intelligence; machine learning; physics informed neural networks

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Tailored Peptide Modifications for Advanced Infection Control Strategies

edited by Piyush Baindara, Ravinder Kumar and

Santi Mandal

submission deadline 30 Sep 2025 | 3 articles | Viewed by 8464 | Submission Open

Keywords: peptide-based vaccines; drug resistance; protein engineering; infectious diseases; antibacterial; antifungal; antiviral; immunotherapies; therapeutics

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Application of Convolutional Neural Networks in Bioimaging and Biosignal Processes

edited by

Sebelan Danishvar

and

Miguel Valencia

submission deadline 30 Sep 2025 | 4 articles | Viewed by 8209 | Submission Open

Keywords: biomedical image/signal analysis; biomedical image/signal processing; new AI architectures; detection and recognition in biomedical image/signals; automated/computer-aided diagnosis using convolutional neural networks

(This special issue belongs to the Section Biosignal Processing)

Computational Genomics for Disease Prediction

edited by

Pietro Pinoli

submission deadline 30 Sep 2025 | 5 articles | Viewed by 7389 | Submission Open

Keywords: computational genomics; disease prediction; genetic markers; high-throughput sequencing; machine learning; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancing Healthcare: Harnessing AI for Diagnostic and Therapeutic Innovations

edited by Wei-Chang Yeh

submission deadline 30 Sep 2025 | 2 articles | Viewed by 6814 | Submission Open

Keywords: artificial intelligence; personalized healthcare; medicine; bioengineering; machine learning

(This special issue belongs to the Section Biosignal Processing)

Biomaterials and Technology for Tumor Engineering

edited by

Girdhari Rijal

and

Narayan Bhattarai

submission deadline 30 Sep 2025 | 1 articles | Viewed by 5949 | Submission Open

Keywords: three-dimensional tumor models; xenograft tumors; cancer cell signatures; H-scan ultrasound; in vivo imaging systems; dye-tagged cell technologies; scaffolds; tumoroids; spheroids; anticancer drugs

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Cartilage and Bone Tissue Engineering: Second Edition

edited by

Francesca Scalera

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5179 | Submission Open

Keywords: cartilage; bone; scaffolds; stem cells; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Dental Implant Reconstruction and Biomechanical Evaluation, 2nd Edition

edited by

Bongju Kim

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3740 | Submission Open

Keywords: dental materials; dental implants; dental prosthesis; implant-supported prosthesis; FEA; FEM; computational modelling; biomechanical characterization

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Computational Modeling in Biomedical Image and Signal Processing—2nd Edition

edited by Xuxin Chen and

Bin Zheng

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3054 | Submission Open

Keywords: computational modeling; quantitative disease markers; medical image processing; image segmentation; biosignal testing; biosignal processes; feature selection; deep learning; computer-aided diagnosis; data standardization; synthetic data generation

(This special issue belongs to the Section Biosignal Processing)

Development of Bioelectrochemical Systems for Environmental Engineering

edited by

Shiue-Lin Li

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3053 | Submission Open

Keywords: bioelectrochemical systems; microbial fuel cells; bioelectrosynthesis; high-added value chemicals; environmental engineering

(This special issue belongs to the Section Biochemical Engineering)

Periodontics and Implant Dentistry

edited by

Sergio Alexandre Gehrke

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2893 | Submission Open

Keywords: periodontics; implantology; technological advances; periodontal health; dental implants; digital planning; guided tissue regeneration; laser therapy; biomaterials; minimally invasive therapies; 3D printing; artificial intelligence; cone beam computed tomography (CBCT); biomodulation; peri-implantitis; tissue engineering; sustainability in dentistry; stem cells; bioprinting; oral rehabilitation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence for Biomedical Signal Processing, 2nd Edition

edited by

Verónica Barroso-García

and

Fernando Vaquerizo-Villar

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2708 | Submission Open

Keywords: aid diagnosis; automatic diagnosis; biomedical signals; biomedical signal processing; deep learning; diseases; explainable artificial intelligence; machine learning; physiological time series; predictive models

(This special issue belongs to the Section Biosignal Processing)

Biomaterials for the Repair and Regeneration of Musculoskeletal Tissue

edited by Christopher Bibbo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2469 | Submission Open

Keywords: musculoskeletal; soft tissue; bone; cartilage; nerve; regenerative medicine; reconstructive surgery

(This special issue belongs to the Section Regenerative Engineering)

Breast Cancer: From Precision Medicine to Diagnostics

edited by Kosuke Kawaguchi

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2276 | Submission Open

Keywords: breast cancer; precision medicine; diagnostics; novel treatment options; personalized treatment; tumor microenvironment; breast imaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Wearable, Flexible, and Integrated Microfluidic-Based Biosensors for Point-of-Care Testing Applications

edited by Madhusudan B. Kulkarni

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2197 | Submission Open

Keywords: biomedical electronic devices; health-monitoring wearables; implantable sensors; bioelectronic medicine; personalized healthcare

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Machine Learning and Artificial Intelligence for Biomedical Applications, 3rd Edition

edited by

Crescenzio Gallo

submission deadline 30 Sep 2025 | 5 articles | Viewed by 2040 | Submission Open

Keywords: artificial intelligence models; biomedicine; machine learning methods; artificial neural networks; precision medicine; personalized health care

(This special issue belongs to the Section Biosignal Processing)

Hydrogels for Biomedical Applications, 2nd Edition

edited by

Pallabi Pal

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1496 | Submission Open

Keywords: drug delivery systems; surface modified biomaterials; self-healing hydrogels; thermoresponsive hydrogels; injectable hydrogels; tissue regeneration; 3D printing; bioactive hydrogels

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Challenges for Managing Glaucoma in the 21st Century

edited by

Karanjit S. Kooner

submission deadline 30 Sep 2025 | 1 articles | Viewed by 885 | Submission Open

Keywords: retinal imaging; artificial intelligence; minimally invasive glaucoma surgeries (MIGSs); telemedicine; neuroimaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Microalgae Biotechnology and Microbiology: Prospects and Applications

edited by Dora Allegra Carbone and Michael Melkonian

submission deadline 30 Sep 2025 | 1 articles | Viewed by 845 | Submission Open

Keywords: microalgae; bacteria; photobioreactor; bioengineering; biomass; wastewater; compounds

(This special issue belongs to the Section Biochemical Engineering)

Advances in Drug Delivery in Cancer Treatment

edited by

Chang Yang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 819 | Submission Open

Keywords: cancer; drug delivery; nanotechnology; targeted therapy; combination therapy; biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Applications of Partial Differential Equations in Bioengineering

edited by

José Alberto Rodrigues

and

Jacinta Serpa

submission deadline 30 Sep 2025 | Viewed by 661 | Submission Open

Keywords: Partial Differential Equations; bioengineering modeling; mathematical biology; tissue engineering; biomechanics; biomedical imaging; fluid dynamics in biology; heat transfer in tissues; drug diffusion modeling; systems biology; epidemic modeling; mathematical models of physiological processes; numerical methods in bioengineering; biological signal processing; computational biology; multiscale modeling; mathematical modeling in regenerative medicine; multi-OMICs in health and disease

Musculoskeletal Bioengineering: Imaging and Computational Modeling in Biomechanics

edited by Geoffrey Handsfield

submission deadline 30 Sep 2025 | 1 articles | Viewed by 528 | Submission Open

Keywords: musculoskeletal bioengineering; biomechanics; imaging; computational modeling; musculoskeletal system; biomedical engineering; orthopedics

(This special issue belongs to the Section Biosignal Processing)

Bioengineering and the Eye—3rd Edition

edited by

Dimitrios Karamichos

submission deadline 30 Sep 2025 | 1 articles | Viewed by 511 | Submission Open

Keywords: stem cell therapies; functional ocular tissue equivalents; biomaterials; 3D bioprinting; tissue engineering

(This special issue belongs to the Section Regenerative Engineering)

Artificial Intelligence and Nanotechnology in Cancer Therapy

edited by Wancheng Guo and

Aarti Sharma

submission deadline 30 Sep 2025 | Viewed by 453 | Submission Open

Keywords: AI; nanotechnology; cancer therapy

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Engineering Biomaterials for Regenerative Medicine Applications

edited by

Ramar Thangam

Heemin Kang

and Venugopal Krishnan

submission deadline 30 Sep 2025 | Viewed by 403 | Submission Open

Keywords: biomaterials; tissue repair; regenerative medicine; stem cells; immune cells; cancer therapy; biomedical devices and implants; tissue regeneration

(This special issue belongs to the Section Regenerative Engineering)

Design and Control Innovations in Prosthetic Hands: From Appearance to Advanced Functionality

edited by

Wenjun (Chris) Zhang

submission deadline 30 Sep 2025 | Viewed by 327 | Submission Open

Keywords: prosthetic hands; biomechanics; neural control systems; soft prosthetics; advanced materials; user-centered design; 3D printing in prosthetics; wireless control systems; mind-controlled prosthetics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Strategies for Ophthalmic Diseases

edited by

Jae Yong Kim

submission deadline 30 Sep 2025 | Viewed by 254 | Submission Open

Keywords: ophthalmic diseases; imaging technology; artificial intelligence; retinal regeneration; corneal implants; drug delivery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Cardiovascular Cell and Gene Therapies: Advances and Translational Challenges

edited by

Emre Bektik

and

Kurt Pfannkuche

submission deadline 30 Sep 2025 | Viewed by 223 | Submission Open

Keywords: myocardial infarction; atherosclerosis; peripheral artery disease (PAD); stem cells differentiation; iPSCs disease modeling; biomaterials; gene delivery; tissue engineering approaches; vascular regeneration; cardiac repair; CRISPR gene editing; bio-scaffolds; bioprinting; microfluidics; organ-on-a-chip; immunomodulation; exosomes; drug delivery; clinical translation

(This special issue belongs to the Section Regenerative Engineering)

Advances in Flexible Bioelectronics: Pioneering Innovations in Healthcare and Medicine

edited by George Luka and Sujung Kim

submission deadline 30 Sep 2025 | Viewed by 221 | Submission Open

Keywords: flexible bioelectronics; bioelectronics; biosensors; wearable microneedle biosensors; soft electronics; stretchable electronics; smart healthcare technologies

(This special issue belongs to the Section Biosignal Processing)

Cardiovascular Models and Biomechanics

edited by

Hwa Liang Leo

submission deadline 30 Sep 2025 | Viewed by 201 | Submission Open

Keywords: vascular mechanics; patient-specific modeling; cardiovascular devices; mechanobiology; experimental methods; computational modeling; machine learning

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Multiscale Modeling in Computational Biomechanics: When Contemporary AI Meets Virtual Human Twin

edited by

Tien Tuan Dao

submission deadline 30 Sep 2025 | Viewed by 181 | Submission Open

Keywords: multiscale modeling; computational biomechanics; AI-driven biomechanics; virtual human twin; generative AI in medicine

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Contribution of Bioprocess Engineering to the Achievement of the UN Sustainable Development Goals (SDGs)

edited by

Dirk Holtmann

submission deadline 30 Sep 2025 | Viewed by 159 | Submission Open

Keywords: bioprocess engineering; sustainability; sustainable development goals (SDGs)

(This special issue belongs to the Section Biochemical Engineering)

Reinforcement Learning and Neuromodulators: Bridging Neuroscience and Artificial Intelligence

edited by

Incheol Seo

and

Hyunsu Lee

submission deadline 30 Sep 2025 | Viewed by 150 | Submission Open

Keywords: reinforcement learning; neuromodulators; neuroscience; Artificial Intelligence (AI)

(This special issue belongs to the Section Biosignal Processing)

Technological Advances in Neurorehabilitation

edited by

Susan Duff

and Andria J. Farrens

submission deadline 30 Sep 2025 | Viewed by 149 | Submission Open

Keywords: assistive technology; neuroimaging; neurorehabilitation; robotics; wearables

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Artificial Intelligence for Medical Diagnosis

edited by Alessio Luschi and Pietro Rubegni

submission deadline 30 Sep 2025 | 1 articles | Viewed by 148 | Submission Open

Keywords: healthcare; medicine; artificial intelligence; deep learning; machine learning; generative AI

(This special issue belongs to the Section Biosignal Processing)

Innovations in Hollow Viscera Imaging: Engineering Breakthroughs and Clinical Translation

edited by

and

submission deadline 30 Sep 2025 | 1 articles | Viewed by 138 | Submission Open

Keywords: hollow viscera imaging; bioengineered diagnostics; AI in endoscopy; minimally invasive devices; functional luminal mapping; smart stents & microsensors; computational biomechanics; clinical translation

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Artificial Intelligence Paradigms for the Detection and Diagnosis of Neurological Diseases

edited by

Yunfeng Wu

submission deadline 30 Sep 2025 | Viewed by 126 | Submission Open

Keywords: biomedical signal processing; artificial intelligence; data mining

(This special issue belongs to the Section Biosignal Processing)

Strategies for Microbial Bioprocess Optimization

edited by

Razieh Rafieenia

submission deadline 30 Sep 2025 | Viewed by 117 | Submission Open

Keywords: metabolic engineering; fermentation; synthetic biology; bioreactor design; synthetic microbial communities; machine learning based process design; renewable substrates; life cycle assessment

(This special issue belongs to the Section Biochemical Engineering)

Artificial Intelligence and Wearable Biosensors for Precision Medicine: Integrating Technology

edited by

Matteo Frigerio

submission deadline 30 Sep 2025 | Viewed by 111 | Submission Open

Keywords: healthcare; gynecology; pelvic floor medicine; pelvic floor rehabilitation; pelvic floor training; laparoscopy; pelvic organ prolapse; urinary incontinence; anal incontinence; overactive bladder; ultrasound; urodynamics; urogynecology; new technologies; pelvic pain; laser; radiofrequency; magnetic stimulation; functional electrical stimulation; biofeedback; vaginal rejuvenation; electronic bladder diaries; sacral neuromodulation; women’ s health

(This special issue belongs to the Section Biosignal Processing)

Three-Dimensional Printing in Modern Dentistry: State of the Art, Benefits and Future Prospects

edited by

Saverio Capodiferro

Massimo Corsalini

and

Giuseppe D'Albis

submission deadline 30 Sep 2025 | Viewed by 111 | Submission Open

Keywords: additive manufacturing; 3D printing; dentistry; CAD/CAM systems; biocompatible materials; clinical applications; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bio-Applications of Engineered Escherichia coli—Second Volume

edited by

Joana Rodrigues

and

Debora Ferreira

submission deadline 30 Sep 2025 | Viewed by 100 | Submission Open

Keywords: Escherichia coli; heterologous production; biosynthetic pathways; value-added compounds; microbial chassis; microbial host; biosensors; whole-cell biosensors; diagnosis tools; therapeutic tools

(This special issue belongs to the Section Biochemical Engineering)

Biomaterial- and Engineering-Based Approaches for Organoids

edited by Xiuzhi Susan Sun

submission deadline 30 Sep 2025 | Viewed by 76 | Submission Open

Keywords: organoids; biomaterials; tissue engineering; three-dimensional bioprinting; microfluidics; extracellular matrix; disease modeling; regenerative medicine; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

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