Advanced Cryopreservation and Innovative Rewarming Strategies for Cells, Tissues, Organs and Organisms
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Cellular and Molecular Bioengineering".
Deadline for manuscript submissions: 10 March 2026
Special Issue Editors
Interests: cryopreservation of large human organs; cryopreservation of the fruit fly; tumor biopsies
Special Issues, Collections and Topics in MDPI journals
Interests: cryobiology; cryopreservation; aquaculture; conservation; biobanking
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cryopreservation and rewarming are essential technologies at the interface of bioengineering, medicine, agriculture and biodiversity conservation. From single cells to complex organs and from model organisms to plants of ecological and agricultural relevance, the capacity to preserve and recover viable systems underpins advances in cell therapies, regenerative medicine, organ transplantation and seed and germplasm banks, as well as the protection of endangered species. Despite important achievements, ensuring structural integrity, functional recovery and scalability across diverse biological systems remains a major scientific and technological challenge.
This Special Issue of Bioengineering, with Guest Editors Estefanía Paredes and Ramón Risco, will provide a multidisciplinary platform for the most recent breakthroughs, innovative methods and visionary perspectives in cryopreservation and rewarming. We welcome contributions covering fundamental mechanisms of cryoinjury and rewarming damage, novel cryoprotective agents and formulations, vitrification strategies, phase-change control, thermal modelling, nanomaterials and microfluidic systems. We also welcome advances in monitoring and imaging technologies that allow the real-time assessment of viability and structural preservation.
Importantly, we invite studies across a wide spectrum of biological models: mammalian cells and tissues, reproductive systems, whole organs, aquatic and terrestrial model organisms and plant tissues that are critical in agriculture and biodiversity conservation. Broader contributions on ecological and astrobiological implications, such as cryobiology in extreme environments and its relevance in space exploration, are also encouraged.
We welcome original research articles, reviews, perspectives and technical reports. By gathering expertise from cryobiology, physics, materials science, engineering, clinical practice, plant sciences and ecology, this Special Issue aims to become a reference point and a catalyst for future collaboration.
We warmly encourage scientists, clinicians and engineers from all fields to submit their work and help advance the global frontier of cryopreservation and innovative rewarming technologies.
Prof. Dr. Risco Ramon
Dr. Estefanía Paredes
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cryopreservation
- vitrification strategies
- rewarming technologies
- cryoprotective agents
- fertility preservation
- plant cryobiology
- aquatic species conservation
- astrobiology and extreme environments
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