Printable Biomaterials from Tissue Engineering to Orthopedics: Fabrication, Mechanical Performance, and Biological Behavior

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 674

Special Issue Editors


E-Mail Website
Guest Editor
Department of Mechanical and Aerospace Engineering (DIMEAS), Politecnico di Torino, 10129 Turin, Italy
Interests: multiscale mechanics of materials; biomaterials; tissue engineering; soft tissue biomechanics; cement composites; bioengineering; biomechanics; computational biomechanics; SEM-EDS; nanoindentation; data-analysis; tensile testing; contact mechanics; surface analysis; materials testing; biodynamics; mechanics of composite materials
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA 01854, USA
Interests: biomaterials; tissue engineering; cardiovascular diseases; biomineralization; wound healing; additive manufacturing; point of care diagnostics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to provide a forum for the discussion of recent advances in printable biomaterials. The rapid advancements in 3D printing and bioprinting technologies have revolutionized the field of biomaterials, enabling the design and fabrication of complex, customized structures with applications that range from tissue engineering to orthopedic implants. Moreover,  the integration of 3D printing with other technologies such as microfluidics and robotics for enhanced fabrication is crucial for the design of novel technologies.

This Special Issue will focus on recent advances in printable biomaterials, encompassing their synthesis, characterization, functionalization, and clinical applications. We welcome contributions that explore the full spectrum of printable biomaterials, including hydrogels, bioceramics, polymers, and composite materials designed for tissue regeneration, orthopedic repairs, drug delivery, and other medical applications. Additionally, this Special Issue will focus on the design, synthesis and characterization of bioinks for the 3D bioprinting of tissues and scaffolds.

Dr. Gianpaolo Serino
Prof. Dr. Gulden Camci-Unal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • advanced printable biomaterials
  • biocompatibility
  • bioactivity
  • mechanical properties
  • physical and chemical properties

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

18 pages, 2158 KB  
Article
Impact of Disinfection and Sterilization on 3D-Printing Resin Performance for Surgical Guides in Cardiac Ablation Surgery
by Rani Kronenberger, Rawan Kazma, Alireza Amirabadi, Leire Viana Uribe, Giacomo Talevi, Görkem Eylül Kaya, Niko Van den Brande, Ramak Hossein Abadi, Kalliopi-Artemi Kalteremidou, Danny Van Hemelrijck, Kitty Baert, Tom Hauffman, Jeroen Soete, Luigi Pannone, Andrea Maria Paparella, Ivan Eltsov, Gian Battista Chierchia, Mark La Meir, Ali Gharaviri and Carlo de Asmundis
Bioengineering 2025, 12(9), 924; https://doi.org/10.3390/bioengineering12090924 - 28 Aug 2025
Viewed by 376
Abstract
Patient-tailored, 3D-printed surgical guides offer significant potential to improve precision and therapeutic efficacy in cardiac ablation surgery. However, reliable post-sterilization material performance presents a critical yet underexplored barrier to clinical adoption. This study investigates how disinfection and sterilization impact the mechanical and thermal [...] Read more.
Patient-tailored, 3D-printed surgical guides offer significant potential to improve precision and therapeutic efficacy in cardiac ablation surgery. However, reliable post-sterilization material performance presents a critical yet underexplored barrier to clinical adoption. This study investigates how disinfection and sterilization impact the mechanical and thermal properties of photopolymer resins. Specimens from two 3D-printing resins (Bioflex A80 MB™, 3Dresyns; MED625FLX™, Stratasys) were treated with four combinations of disinfection techniques (low-temperature manual cleaning; high-temperature machine washing) and sterilization techniques (H2O2 vs. autoclaving). We assessed post-sterilization properties by mechanical (material integrity, bending tests), thermal (differential scanning calorimetry, thermogravimetric analysis), and viscoelastic (dynamic mechanical analysis) studies. Statistical analysis was performed using one-way ANOVA with Bonferroni post hoc tests (α = 0.05). From this preliminary study, we conclude that MED625FLX maintains integrity and flexibility across all tested disinfection and sterilization methods. Bioflex A80 MB is only suitable for low-temperature disinfection–sterilization, as high-temperature treatments cause surface cracking. Neither resin is appropriate for cryogenic conditions due to the risk of brittleness. Further research into post-sterilization properties is essential to ensure the safety and clinical reliability of these materials in cardiac procedures. Full article
Show Figures

Figure 1

Back to TopTop