Engineering Stem Cells and Their Derivatives for Wound Healing and Tissue Regeneration
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: 25 January 2026 | Viewed by 14
Special Issue Editor
Interests: regenerative medicine; biomaterials; drug delivery; stem cells; cartilage; bone; soft (adipose) tissue; aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Stem cells hold great promise for regenerative medicine and wound healing due to their capacities of self-renewal, pluri- or multipotency, and immunomodulation. Recent advances in stem cell engineering suggest a potential contribution to development of novel therapeutic strategies for different diseases and defects. Furthermore, the use of stem cell derivatives, such as extracellular vesicles, as therapeutic agents represents an emerging area in regenerative medicine, which minimizes the risk of immunogenicity, host rejection, and tumorigenicity that are commonly seen in cell-based therapies, and also represent a possible off-the-shelf product for tissue and organ repair. This Special Issue of Bioengineering summarizes recent advancements in stem cell therapies for tissue regeneration and wound healing and spans three major areas: (1) control of stem cell fate (adult stem cells and pluripotent stem cells such as iPSCs) through biomaterial design, gene editing or other innovative technologies, (2) immunomodulation of stem cells and their functional sub-populations via paracrine signaling, and (3) the delivery of stem cells and extracellular vesicles towards translational and preclinical applications. New developments in subjects including, but not limited to, scaffolding biomaterials, drug delivery, and gene editing utilized to regenerate various tissue types will be considered for publication.
Dr. Yueh Hsun Kevin Yang
Guest Editor
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Keywords
- stem cells
- extracellular vesicles
- biomaterials
- immunoengineering
- gene editing
- regenerative medicine
- wound healing
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