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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Digital Technologies to Improve Diagnostic Cytopathology: Future Outlook

edited by

Enrico Giarnieri

submission deadline 31 Jul 2025 | Viewed by 108 | Submission Open

Keywords: machine learning; cytopathology; digital cytology; computer-aided diagnosis; virtual reality; natural language process

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Microalgal Systems for a Greener Future

edited by

Ana Filipa Cruz Esteves

and

Alok Kumar Patel

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1211 | Submission Open

Keywords: artificial intelligence; machine learning; bioprocessing; circular bioeconomy; production value addition; biomass valorization; microalgal cultivation systems; sustainable bioprocessing

(This special issue belongs to the Section Biochemical Engineering)

Current Trends in Robotic Rehabilitation Technology

edited by Serena Filoni,

Raffaello Pellegrino

and

Eduardo Palermo

submission deadline 25 Aug 2025 | Viewed by 830 | Submission Open

Keywords: rehabilitation robotics; machine learning and artificial intelligence; neurological diseases; neuroplasticity; virtual reality for rehabilitation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Platforms for Drug Delivery

edited by Anam Ahsan

submission deadline 25 Aug 2025 | Viewed by 343 | Submission Open

Keywords: biomaterials; drug delivery; nanotechnology; nanobiotechnology; bioengineering platforms; targeted drug delivery; chemotherapy; bioconjugation; disease management; therapeutic agents

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Stem Cell Bioprocessing

edited by Mariana Petronela Hanga and Eirini Theodosiou

submission deadline 25 Aug 2025 | Viewed by 305 | Submission Open

Keywords: bioprocessing of stem cells; microcarriers; biomaterials; stem cell therapy; cultivated meat; ATMPs; extracellular vesicles

(This special issue belongs to the Section Regenerative Engineering)

Mathematical Models for Medical Diagnosis and Testing

edited by

Peiyuan Zhou

and

Andrew K. C. Wong

submission deadline 30 Aug 2025 | 1 articles | Viewed by 1164 | Submission Open

Keywords: mathematical modeling; machine learning; artificial intelligence; pattern discovery; medical diagnosis; clinical data analysis; predictive analytics; explainable AI; statistical modeling; anomaly detection; rare disease detection; knowledge discovery; health informatics

(This special issue belongs to the Section Biosignal Processing)

Wearable Sensors and Measurement Systems for Human Physiology Monitoring

edited by

Manob Saikia

submission deadline 31 Aug 2025 | 9 articles | Viewed by 25143 | Submission Open

Keywords: wearable sensor; measurement system; bioinstrumentation; wearable neuroimaging; flexible biosensors; bioelectronics; Internet of Things in healthcare; prototyping; signal processing; physiological measurement; parameters; injury prevention; rehabilitation; wellness monitoring; chronic disease

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence for Computer-Aided Detection in Biomedical Applications

edited by

Lawrence Chan

submission deadline 31 Aug 2025 | 13 articles | Viewed by 22793 | Submission Open

Keywords: artificial intelligence; computer-aided detection; CAD; biomedical applications; biomedical engineering; radiology; medical imaging; bioinformatics; deep learning; machine learning; disease diagnosis

(This special issue belongs to the Section Biosignal Processing)

AI-Powered Diagnosis and Treatment Plans in Dentistry and Orofacial Fields

edited by

Antonino Lo Giudice

, Rosalia Leonardi,

Victor Díaz-Flores García

and

Yolanda Freire

submission deadline 31 Aug 2025 | 11 articles | Viewed by 19037 | Submission Open

Keywords: artificial intelligence; AI; digital dentistry; digital systems; CBCT; CAD-CAM

(This special issue belongs to the Section Biosignal Processing)

Mathematical and Computational Modeling of Cancer Progression

edited by

Leili Shahriyari

and

Pasquale De Luca

submission deadline 31 Aug 2025 | 6 articles | Viewed by 14161 | Submission Open

Keywords: computational oncology; cancer progression; cancer treatments; mechanistic modeling of cancer; integration of machine learning and mechanistic modeling

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancements in Artificial Intelligence for Wearable Devices: A New Perspective on Healthcare Applications

edited by

Maria Giovanna Bianco

Salvatore Pullano

and

Syed Kamrul Islam

submission deadline 31 Aug 2025 | 4 articles | Viewed by 8261 | Submission Open

Keywords: wearable devices; artificial lntelligence; machine learning; biomedical signal processing; deep learning; bio-inspired systems; biosensor devices

(This special issue belongs to the Section Biosignal Processing)

Fabrication of Biomaterials to Develop Tissue Engineering Scaffolds and Medical Devices

edited by

Iruthaya Pandi Selestin Raja

submission deadline 31 Aug 2025 | 3 articles | Viewed by 6958 | Submission Open

Keywords: tissue engineering; biocompatible polymers; nanomaterials; biofabrication; bioprinting; photobiomodulation patches; smart medical devices; cell– biomaterial interaction

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Applications of Genomic Technology in Disease Outcome Prediction

edited by

Sulev Koks

submission deadline 31 Aug 2025 | 3 articles | Viewed by 5772 | Submission Open

Keywords: genomic technology; disease outcome prediction; genetic analysis; genetic variations; genome-wide association studies (GWAS); genetic risk factors; biomarkers; genetic risk score; next-generation sequencing (NGS); rare genetic variants; personalized medicine; treatment strategies.

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Cardiovascular Hemodynamic Characterization: Prospects and Challenges

edited by

and

submission deadline 31 Aug 2025 | 4 articles | Viewed by 4758 | Submission Open

Keywords: cardiovascular system; biofluid mechanics; hemodynamics; in-silico modeling; computational fluid dynamics; in-vitro modeling; flow visualization and tracking

New Sights of EEG and Brain Diseases: Updates and Directions

edited by

Carlos Trenado

and Christian Penaloza

submission deadline 31 Aug 2025 | 3 articles | Viewed by 4631 | Submission Open

Keywords: EEG; brain diseases; neuropsychiatric conditions; prosthetics

(This special issue belongs to the Section Biosignal Processing)

Application of Artificial Intelligence in Complex Diseases

edited by Yan Zhu

submission deadline 31 Aug 2025 | 2 articles | Viewed by 4516 | Submission Open

Keywords: artificial intelligence; machine learning; complex diseases; healthcare; diagnostics; predictive modeling; medical imaging; ethics in AI

(This special issue belongs to the Section Biosignal Processing)

Microfluidics and Sensor Technologies in Biomedical Engineering

edited by Ali Asgar Bhagat

submission deadline 31 Aug 2025 | 4 articles | Viewed by 4478 | Submission Open

Keywords: lab-on-a-chip; microfluidics fabrication; MEMS; point-of-care diagnostics; biosensors; materials

(This special issue belongs to the Section Biosignal Processing)

New Sights of Deep Learning and Biomedical Image Processing: Updates, Applications, and Directions

edited by Yuxuan Cheng and Lin Shan

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3255 | Submission Open

Keywords: deep learning; biomedical imaging; optical coherence tomography; microscopy; X-ray; CT; MRI; ultrasound; endoscopy; laparoscopy; cystoscopy; image classification; image segmentation; biomarker detection; image registration; multimodal medical imaging

(This special issue belongs to the Section Biosignal Processing)

Engineered Analysis of Tissue Mechanics and Blood Flow for Cardiovascular Host-Device Interaction

edited by Karen May-Newman

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3105 | Submission Open

Keywords: solid– fluid mechanics; stress; strain; shear; flow; thrombus formation; hemocompatibility; medical device

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Computational Biofluid Dynamics

edited by

Tinghui Zheng

Peng Wu

and Jun Wen

submission deadline 31 Aug 2025 | 4 articles | Viewed by 3091 | Submission Open

Keywords: biofluids; cardiovascular and pulmonary systems; machine learning; critical care

(This special issue belongs to the Section Biosignal Processing)

Ultrasound Elastography in Biomedicine: Principles, Techniques and Applications

edited by Abbas Samani

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2770 | Submission Open

Keywords: ultrasound elastography; motion tracking; inverse problems; quasi-static elastography; strain imaging; stiffness imaging; dynamic elastography; shear wave elastography; transient elastography; instrumentation; clinical applications

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Genomics Research

edited by Chien-Wei (Masaki) Lin

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2549 | Submission Open

Keywords: genomics data analysis; NGS; AI; machine learning; multi-omics integration; single-cell sequencing; precision medicine

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Recent Advances in Cancer Bioinformatics

edited by

Pritam Kumar Panda

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1923 | Submission Open

Keywords: cancer bioinformatics; computational modeling; cancer biophysics; single-cell sequencing; whole exome sequencing (WES); whole genome sequencing (WGS); RNA sequencing (RNA-seq); tumor heterogeneity; cancer genomics; personalized medicine; predictive modeling; cancer pathways; oncogenesis; tumor microenvironment; bioinformatics tools; omics integration

(This special issue belongs to the Section Biosignal Processing)

Biomechanics and Mechanobiology in Cell and Tissue Engineering

edited by

Aaron Baker

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1545 | Submission Open

Keywords: biomechanics; mechanobiology; tissue engineering; cell engineering; vascular; cardiovascular; neuroengineering; stem cells; cancer; osteoarthritis; bone

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancing Treatment for Brain Tumors

edited by

Min D. Tang-Schomer

and Joanna J. Gell

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1438 | Submission Open

Keywords: brain tumor model; tumor microenvironment; brain microenvironment; personalized medicine; xenograft model; molecular profiling; glioblastoma; ependymoma; medulloblastoma; astrocytoma; pediatric brain tumor

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Modern Medical Imaging in Disease Diagnosis Applications

edited by Carlo Cosimo Quattrocchi and

Marco Parillo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: radiology; diagnostic imaging; contrast media; computed tomography; magnetic resonance imaging; ultrasound; artificial intelligence in medical imaging; radiomics

(This special issue belongs to the Section Biosignal Processing)

Innovative Approaches: Harnessing Virtual Reality for Assessment and Rehabilitation in Stroke and Aging-Related Disorders

edited by Gauthier Everard and

Charles Sebiyo Batcho

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1194 | Submission Open

Keywords: virtual reality; assessment; rehabilitation; stroke; neurorehabilitation; older adults; kinematics; cognition

(This special issue belongs to the Section Biosignal Processing)

Advances and Innovations in Wound Repair and Regeneration

edited by

Shiva Akbarzadeh

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1172 | Submission Open

Keywords: engineered skin graft; three-dimensional skin printing; skin grafting in animal models; dermal substitutes

(This special issue belongs to the Section Regenerative Engineering)

Multiclass Prediction and Assisted Diagnosis of Mental Disorders Based on Eye Movement and Other Physiological Signals

edited by Quan Wang

submission deadline 31 Aug 2025 | 1 articles | Viewed by 862 | Submission Open

Keywords: physiological signals; mental disorders; eye movement

(This special issue belongs to the Section Biosignal Processing)

IoT Technology in Bioengineering Applications: Second Edition

edited by Mihaela Hnatiuc and Larbi Boubchir

submission deadline 31 Aug 2025 | 1 articles | Viewed by 856 | Submission Open

Keywords: robotic device; signal processing; image processing; communication protocol; embedded system; smart sensors; cloud/FOG; predictive methods; monitoring; process optimization; diagnosis; implant; tele surgery; teleconsultation; telemonitoring

(This special issue belongs to the Section Biosignal Processing)

Tendon/Ligament and Enthesis Injuries: Repair and Regeneration

edited by Dai Fei Elmer Ker, Jingyu Shi and Bingyang Dai

submission deadline 31 Aug 2025 | 1 articles | Viewed by 854 | Submission Open

Keywords: tendon; ligament; enthesis; drug delivery; therapeutics; biomaterials; tissue engineering; musculoskeletal animal models

(This special issue belongs to the Section Regenerative Engineering)

Machine Learning and Artificial Intelligence in Pediatric Healthcare

edited by

Hammad Ashraf Ganatra

submission deadline 31 Aug 2025 | Viewed by 788 | Submission Open

Keywords: artificial intelligence; machine learning; pediatrics; natural language processing; diagnostics

(This special issue belongs to the Section Biosignal Processing)

The Next Generation of Tissue Engineering

edited by Tetsuya Imamura

submission deadline 31 Aug 2025 | 1 articles | Viewed by 767 | Submission Open

Keywords: tissue engineering; mesenchymal stem cells; engineered cell sheets; biofabricated cell structures

(This special issue belongs to the Section Regenerative Engineering)

New Trends in Biomechanical Modeling in Musculoskeletal Disorders and Diseases

edited by

Philippe Gorce

submission deadline 31 Aug 2025 | 1 articles | Viewed by 730 | Submission Open

Keywords: musculoskeletal disorders; musculoskeletal diseases; injury biomechanics; muscle biomechanics dynamic and kinematic modeling; gait and posture; muscle electromyography; motion analysis; postural control and balance; occupational health; occupational ergonomics; sport medicine; sport performance; quality of life

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Novel Imaging Techniques in Radiotherapy

edited by

Zijian Deng

and Junwei Shi

submission deadline 31 Aug 2025 | 1 articles | Viewed by 609 | Submission Open

Keywords: radiotherapy; imaging; tumor localization; treatment assessment; radiation toxicity

(This special issue belongs to the Section Biosignal Processing)

Transcranial Direct Current Stimulation: Bridging Bioengineering and Neuroscience for Brain Health

edited by

Josué Fernández-Carnero

and

Víctor Navarro López

submission deadline 31 Aug 2025 | 1 articles | Viewed by 496 | Submission Open

Keywords: transcranial direct current stimulation (tDCS); neuroplasticity; neuromodulation

(This special issue belongs to the Section Biosignal Processing)

Surrogate Biomedical Data Generation

edited by

Saeid Sanei

and Tracey KM Lee

submission deadline 31 Aug 2025 | Viewed by 428 | Submission Open

Keywords: surrogate; augmentation; deep learning; machine learning; biomedical images; biomedical signals; edge systems; testing

(This special issue belongs to the Section Biosignal Processing)

Transforming Regenerative Medicine: Innovations in Bioengineered Extracellular Vesicles

edited by

Byeong-Cheol Ahn

and

Prakash Gangadaran

submission deadline 31 Aug 2025 | Viewed by 421 | Submission Open

Keywords: extracellular vesicles (EVs); targeted drug delivery; chemical modification; genetic modification; ligand attachment; click chemistry; multifunctional peptides; hybrid exosome-liposome; bioengineering; regenerative medicine; therapeutic applications; biomanufacturing

(This special issue belongs to the Section Regenerative Engineering)

Recent Trends and Future Directions in Biosignal Processing and Applications: State-of-the-Art Reviews

edited by

Andrea Cataldo

and Raissa Schiavoni

submission deadline 31 Aug 2025 | Viewed by 389 | Submission Open

Keywords: biosignal processing; biomedical engineering healthcare; biosignals; signal processing; data analysis; biomedical imaging; biosensors; wearable sensors; artificial intelligence (AI); machine learning (ML); predictive modeling; personalized medicine; early disease detection

(This special issue belongs to the Section Biosignal Processing)

Augmented Reality, Virtual Reality and Extended Reality Solutions for Biomedical Applications

edited by

Vera Gramigna

and Arrigo Palumbo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 331 | Submission Open

Keywords: augmented reality (AR); virtual reality (VR); extended reality (XR); biomedicine; human– robot interaction; technology in healthcare; medical imaging; surgical simulation; surgical navigation; robotic-assisted surgery; rehabilitation technology; neurological disorders’ treatment; pain management; personalized healthcare; artificial intelligence (AI) in medicine; human– computer interaction in healthcare; digital health technologies

(This special issue belongs to the Section Biosignal Processing)

Extended Reality Technologies, Medical Robotics Solutions, and Deep Learning in Translational Medicine—2nd Edition

edited by

Fabrizio Cutolo

submission deadline 31 Aug 2025 | Viewed by 265 | Submission Open

Keywords: extended reality interfaces for surgical navigation and surgical training; extended reality interfaces for translational medicine; computer vision solutions for healthcare; smart sensors for image-guided surgery; visual and multimodal tracking algorithms in translational medicine; wearable-friendly human-computer interaction solutions in healthcare

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Sights of Image Processing and Digital Models in Biomedicine

edited by Seyed Jalalddelin Mousavirad and

Diego Oliva

submission deadline 31 Aug 2025 | Viewed by 256 | Submission Open

Keywords: image processing and computer vision; deep learning; artificial intelligence; biomedicine

(This special issue belongs to the Section Biosignal Processing)

The Encapsulation of Bioactive Molecules: The Current and Future Potential for Biotechnology Applications

edited by

Edward Weaver

submission deadline 31 Aug 2025 | Viewed by 204 | Submission Open

Keywords: encapsulation; delivery system; targeted delivery; bioactive molecule; viral vector

(This special issue belongs to the Section Biochemical Engineering)

Computational Intelligence for Healthcare

edited by

Jiaojiao Wang

, Chee Wei Tan and Qingpeng Zhang

submission deadline 31 Aug 2025 | Viewed by 190 | Submission Open

Keywords: artificial intelligence; big data analytics; generative models; pathogen tracking and tracing; chronic disease prediction and management; predictive modeling; bioinformatics; pandemic preparedness; IoT-enabled biosensors; health disparities and ethics; multi-modal data fusion

(This special issue belongs to the Section Biosignal Processing)

New Sight of Deep Learning in Bioengineering: Updates and Future Directions (2nd Edition)

edited by

Tao Zhang

submission deadline 31 Aug 2025 | Viewed by 189 | Submission Open

Keywords: deep learning; biomedicine; robotics and biomechanics; biomedical imaging; biosignal processing

(This special issue belongs to the Section Biosignal Processing)

Advancements in Human–Machine Interaction and Robotics: From Biomechanics to Cognitive Neuroscience

edited by Jiejunyi Liang

submission deadline 31 Aug 2025 | Viewed by 180 | Submission Open

Keywords: human-machine interaction; robotics; biomechanics; cognitive neuroscience; anthropomorphic robotic systems

Microfluidic Platform for Bioengineering and Translational Research

edited by

Sudip K. Das

submission deadline 31 Aug 2025 | Viewed by 159 | Submission Open

Keywords: microfluidic devices; biosensors; disease diagnosis; organ-on-chip platforms; drug discovery; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Through Computer-Aided Drug Design

edited by

Chin-Hung Lai

and

Suraj Narayan Mali

submission deadline 31 Aug 2025 | Viewed by 155 | Submission Open

Keywords: molecular docking; molecular dynamics; QSAR; AI; NSAIDs

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Wearable Technologies and Health Informatics: Advancements in Bioengineering

edited by

Iqram Hussain

and

Jahowa Islam

submission deadline 31 Aug 2025 | Viewed by 95 | Submission Open

Keywords: wearable sensors; health monitoring; large language model; electronic health record; flexible sensors; sensors; artificial intelligence; smart healthcare; data privacy; machine learning; sensor applications; energy efficiency; health diagnostics; wearable signal processing (EEG; ECG; EMG; PPG; and IMU); internet of things (IoT); activity recognition; biomedical techniques; sleep medicine; smart grid; data science; smart surveillance

(This special issue belongs to the Section Biosignal Processing)

Advanced Techniques and Applications in Burn Reconstruction: A Bioengineering Perspective

edited by Booker T. King and Rodney K. Chan

submission deadline 31 Aug 2025 | Viewed by 95 | Submission Open

Keywords: burn reconstruction; bioprinting; tissue transfer; regenerative medicine; stem cell therapy; wound heal; micro-surgical techniques; nanotechnology-enabled strategies

(This special issue belongs to the Section Regenerative Engineering)

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