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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Medical 3D Vision: Voxels and Beyond

edited by Jiancheng Yang, Hongwei Li and Hieu Le

submission deadline 30 Jun 2026 | 3 articles | Viewed by 14082 | Submission Open

Keywords: medical 3D vision; artificial intelligence for health; 3D medical image analysis; voxel-based imaging; point clouds; mesh-based analysis; graph neural networks; implicit representations; deep geometric learning; interventional imaging; healthcare applications; digital twins

(This special issue belongs to the Section Biosignal Processing)

AI and Data Science in Bioengineering: Innovations and Applications

edited by

Muneer Ahmad

submission deadline 30 Jun 2026 | 9 articles | Viewed by 13655 | Submission Open

Keywords: AI; data science; bioengineering; biomedical engineering; predictive modeling; machine learning; smart biomaterials; tissue engineering

(This special issue belongs to the Section Biosignal Processing)

Biomedical Application of Big Data and Artificial Intelligence—Second Edition

edited by

Yan Pei

and

Jijiang Yang

submission deadline 30 Jun 2026 | 4 articles | Viewed by 11610 | Submission Open

Keywords: artificial intelligence; big data; image processing; data mining; soft computing; bioinformatics; bioengineering; healthcare

(This special issue belongs to the Section Biosignal Processing)

Label-Free Cancer Detection

edited by

Raphaël Canadas

submission deadline 30 Jun 2026 | 5 articles | Viewed by 11118 | Submission Open

Keywords: label-free; microfluidics; biomarkers; cancer; non-invasive; biosensors; nanotechnology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

3D Cell Culture Systems: Current Technologies and Applications

edited by

Peggy Stock

submission deadline 30 Jun 2026 | 5 articles | Viewed by 10570 | Submission Open

Keywords: 3D cell culture; tissue engineering; biomaterials; drug discovery; cancer research; regenerative medicine; scaffold technology; high-throughput screening; organoids; in vitro models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Tissue Engineering and Regenerative Medicine Strategies for Biomedical Engineering

edited by Hun-Jin Jeong and

Solaiman Tarafder

submission deadline 30 Jun 2026 | 3 articles | Viewed by 10020 | Submission Open

Keywords: tissue engineering; regenerative medicine; bioprinting; microfluidics; tissues on chip

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Integrative Bioengineering in Orthopedic Surgery: From Regenerative Constructs to Precision Arthroplasty

edited by Man Soo Kim

submission deadline 30 Jun 2026 | 2 articles | Viewed by 9733 | Submission Open

Keywords: orthopedic bioengineering; tissue-engineered constructs; stem cell therapy; robotic surgery; AI-guided arthroplasty; smart implants; biomechanical modeling; scaffold-implant hybrid systems; regenerative surgery; precision orthopedics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Computational Imaging and Artificial Intelligence for Biomedical and Clinical Applications

edited by Nan Meng,

Jason Pui Yin Cheung

and Junming Shao

submission deadline 30 Jun 2026 | 7 articles | Viewed by 9651 | Submission Open

Keywords: computational imaging; artificial intelligence; deep learning; medical image analysis; medical diagnosis

(This special issue belongs to the Section Biosignal Processing)

Next-Generation Diagnostic and Therapy Systems for Neurodegenerative Diseases

edited by

Raji Sundararajan

and

Miad Faezipour

submission deadline 30 Jun 2026 | 3 articles | Viewed by 9006 | Submission Open

Keywords: Alzheimer's disease; Parkinson's disease; machine learning; deep learning; neurostimulation; neuromodulation; artificial intelligence models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Sights of Deep Learning and Digital Model in Biomedicine

edited by

John A. St. Cyr

submission deadline 30 Jun 2026 | 5 articles | Viewed by 8636 | Submission Open

Keywords: deep learning; digital model; biomedicine

(This special issue belongs to the Section Biosignal Processing)

Advanced Wearable Sensors for Human Gait Analysis

edited by

Tong Li

, Qingguo Li and Bingfei Fan

submission deadline 30 Jun 2026 | 4 articles | Viewed by 8488 | Submission Open

Keywords: wearable sensors; human movement analysis; rehabilitation; sport science; sensor fusion; machine learning

(This special issue belongs to the Section Biosignal Processing)

Emerging Nanomaterials and Nanotechnologies for Biomedical and Related Applications

edited by

Dipak Maity

and

Mangilal Agarwal

submission deadline 30 Jun 2026 | 4 articles | Viewed by 8213 | Submission Open

Keywords: nanomaterials; nanotechnologies; biomedical applications; drug delivery systems; biosensors; tissue engineering; cancer therapeutics; diagnostics; biomedical imaging; photothermal therapy; chemodynamic therapy; cardiovascular diseases; infection control; neurological diseases; orthopedics

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Engineering Neural Motor Control: From Mechanisms to Neural Interfaces

edited by Eizo Miyashita and Yuki Ueyama

submission deadline 30 Jun 2026 | 3 articles | Viewed by 7932 | Submission Open

Keywords: systems neuroscience; computational neuroscience; motor control; motor learning; motor dysfunction; rehabilitation; neuromodulation; human argumentation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Cardiac MRI

edited by

Qing Zou

and Gerald Greil

submission deadline 30 Jun 2026 | 4 articles | Viewed by 7098 | Submission Open

Keywords: cardiac MRI; post-processing; deep learning; fast imaging; novel sequences

(This special issue belongs to the Section Biosignal Processing)

Synthesis, Characterization, and Application of Biomacromolecules and Biobased Polymers

edited by

Shichao Ding

and Wenzhuo Chen

submission deadline 30 Jun 2026 | 5 articles | Viewed by 7061 | Submission Open

Keywords: biomacromolecules; biobased polymers; synthesis; characterization; engineered biomaterial; biopharmaceuticals

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Medical Image Processing and Segmentation, Third Edition

edited by

Bernard Chiu

submission deadline 30 Jun 2026 | 7 articles | Viewed by 6848 | Submission Open

Keywords: medical image processing; image segmentation; computer-aided diagnosis; image-guided surgery; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Biological Wastewater Treatment and Resource Recovery, 2nd Edition

edited by

Omprakash Sarkar

Naresh Kumar Amradi

and

J. Shanthi Sravan

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5840 | Submission Open

Keywords: wastewater treatment; nutrient recovery; bioenergy generation; biobased products; anaerobic digestion; volatile fatty acids; bioammonium; bioelectricity

(This special issue belongs to the Section Biochemical Engineering)

Retinal Biomarkers: Seeing Diseases in the Eye

edited by

Paul Constable

and

Hugo F. Posada-Quintero

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4218 | Submission Open

Keywords: biomarker; retina; structure; function; machine learning; deep learning; classification; imaging; electrophysiology

(This special issue belongs to the Section Biosignal Processing)

Soft and Flexible Sensors for Biomedical Applications

edited by Martina Maselli and Parisa Abadi

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4050 | Submission Open

Keywords: stretchable electronics; flexible sensors; biomedical applications; wearable devices; conformable materials; health monitoring

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Contactless Technologies for Patient Health Monitoring

edited by

Mark van Gastel

, Wim Verkruysse,

Xi Long

and Rick Bezemer

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3043 | Submission Open

Keywords: contactless monitoring; unobtrusive sensing; physiological measurements; contextual monitoring; clinical decision support

(This special issue belongs to the Section Biosignal Processing)

Advanced Polymeric Materials for Bone, Cartilage, and Skeletal Muscle Regeneration

edited by

Jian Li

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2990 | Submission Open

Keywords: polymeric materials; bone regeneration; cartilage repair; skeletal muscle regeneration; 3D bioprinting; drug delivery systems; biodegradable polymers; smart materials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Application of Artificial Intelligence in Oncologic PET Imaging

edited by

Angelo Castello

Seyed Ali Mirshahvalad

and

Adam Farag

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2889 | Submission Open

Keywords: positron emission tomography (PET); PET/CT; PET/MRI; artificial intelligence; radiomics; machine learning; deep learning; convolutional neural networks; auto-segmentation; quantification; theranostics; novel radiopharmaceuticals

(This special issue belongs to the Section Biosignal Processing)

Tissue Engineering for Regenerative Dentistry, 2nd Edition

edited by

Carlos Fernando Mourão

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2031 | Submission Open

Keywords: regenerative dentistry; autologous blood concentrates; platelet-rich fibrin (PRT); stem cells; bioactive biomaterials; tissue engineering; oral and maxillofacial regeneration; extracellular matrix; translational research; dental tissue repair

(This special issue belongs to the Section Regenerative Engineering)

Musculoskeletal Bioengineering: Imaging and Computational Modeling in Biomechanics—Second Edition

edited by Geoffrey Handsfield and

Maury L. Hull

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1908 | Submission Open

Keywords: musculoskeletal bioengineering; biomechanics; imaging; computational modeling; musculoskeletal system; biomedical engineering; orthopedics

(This special issue belongs to the Section Biosignal Processing)

Oral Wound Healing and Material Engineering

edited by

Steven L. Goudy

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1807 | Submission Open

Keywords: oral; healing; regeneration; mucosa; bone; biomaterial

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Mesenchymal Stem Cells for Regenerative Medicine

edited by Kyungsook Kim and

Luis G. Villa-Diaz

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1505 | Submission Open

Keywords: mesenchymal stem cell (MSC) engineering; genetic modification of MSCs; MSC biomaterial integration; surface modification of MSCs; MSC sheet engineering; scaffold-free MSC delivery; MSC bioactive factor secretion; direct MSC reprogramming; engineered MSC characterization and differentiation; improved protocols for MSC derivation from tissues and pluripotent; clinical translation strategy of engineered MSCs

(This special issue belongs to the Section Regenerative Engineering)

Machine Learning-Driven Innovations in Predictive Healthcare

edited by

Julfikar Haider

, Sang Won Park and

Mominul Ahsan

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1447 | Submission Open

Keywords: machine learning; clinical data analysis; medical decision support; disease prediction; personalized medicine

(This special issue belongs to the Section Biosignal Processing)

Machine Learning in Precision Oncology: Innovations and Applications

edited by Sheida Nabavi and

Jun Bai

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1424 | Submission Open

Keywords: generative models in oncology; machine learning in cancer research; large language models in cancer; diffusion models; synthetic medical data; AI-driven cancer diagnosis; deep learning for oncology; personalized cancer therapy; cancer imaging and reconstruction; predictive modeling in oncology; data augmentation in medical imaging; bioinformatics and generative AI; multi-omics integration; digital pathology and AI; computational oncology; clinical decision support systems

(This special issue belongs to the Section Biosignal Processing)

AI and Data Science in Biomedicine: Powering the Next Generation of Diagnostics and Therapies

edited by

Hongqing Yu

and

Yifan Zhao

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1022 | Submission Open

Keywords: AI in biomedicine; data science; machine learning; diagnostics; personalized medicine; predictive analytics

(This special issue belongs to the Section Biosignal Processing)

Emerging Roles of Large Language and Foundation Models in Pathology

edited by Zeynettin Akkus

submission deadline 30 Jun 2026 | 1 articles | Viewed by 959 | Submission Open

Keywords: large language models (LLMs); foundation models; digital pathology; histopathology image analysis; self-supervised learning; multi-modal AI; clinical decision support; retrieval-augmented generation (RAG); explainable AI (XAI); translational pathology

(This special issue belongs to the Section Biosignal Processing)

Advancements in Imaging and Sensing of Single Multi-Functional Nanoparticles, Viruses and Organelles

edited by Michelle A. Digman, Qimei Zhang, Jian Yang and

Georgios Alexandrakis

submission deadline 30 Jun 2026 | 1 articles | Viewed by 714 | Submission Open

Keywords: super-resolution microscopy; hyperspectral imaging; nanopore sensing; plasmonics; lipid nanoparticles; liposomes; quantum dots; virus; cell organelles

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Biomedical Engineering for Facial Reconstruction

edited by James F. Thornton

submission deadline 30 Jun 2026 | 1 articles | Viewed by 686 | Submission Open

Keywords: facial reconstruction; biomedical engineering; dermal regeneration templates; biodegradable temporizing matrix (BTM); integra dermal regeneration matrix; tissue engineering; biomaterials; wound healing; soft tissue regeneration; vascularization; reconstructive surgery innovation; personalized medicine; hyperbaric oxygen treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bio-Scaffold Engineering for Soft Tissue Regenerative Medicine

edited by Zhonggang Feng

submission deadline 30 Jun 2026 | Viewed by 555 | Submission Open

Keywords: bio-scaffold engineering; decellularization; 3D bio-printing; hydrogel; polymer; natural materials; electrospinning; mechanical environment; cellular homeostasis; simulation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Biomedical Imaging, Third Edition

edited by

Cuneyt M. Alper

submission deadline 30 Jun 2026 | Viewed by 450 | Submission Open

Keywords: imaging innovations; advances in imaging CT; scans MRI; ultrasound nuclear medicine; PET fluoroscopy; interventional radiology; combined imaging modalities; automated segmentation; machine learning

(This special issue belongs to the Section Biosignal Processing)

Novel Strategies in Dentin/Pulp Regeneration Through Tissue Engineering

edited by Roda Seseogullari-Dirihan

submission deadline 30 Jun 2026 | Viewed by 435 | Submission Open

Keywords: dentin/pulp regeneration; stem cell; tissue engineering; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Scale-Up Production, Standardization and Biomaterialomics of Extracellular Vesicles

edited by

Esra Cansever Mutlu

Artemis Stamboulis

and

Joshua Price

submission deadline 30 Jun 2026 | Viewed by 395 | Submission Open

Keywords: extracellular vesicles; exosomes; regenerative medicine; drug delivery; nanoscale flow cytometry; cryo-electron microscopy; mass spectrometry; multi-omics integration; AI and machine learning; FAIR data principles

(This special issue belongs to the Section Regenerative Engineering)

The Biophysics of Vocal Onset, 2nd Edition

edited by

Sten Ternström

and

Claudia Manfredi

submission deadline 30 Jun 2026 | Viewed by 387 | Submission Open

Keywords: biophysics; vocal onset; intraglottal pressure; transglottal flow; glottal area; intraglottal turbulence; videokymography; glottography; high-speed imaging; voice acoustics; voice synthesis; machine learning

(This special issue belongs to the Section Biosignal Processing)

Intelligent Methods in Medical Image Processing and Segmentation

edited by

Adam Adamopoulos

and

Efstratios Karavasilis

submission deadline 30 Jun 2026 | Viewed by 305 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; medical imaging; molecular and cellular imaging; computer assisted diagnosis and prognosis

(This special issue belongs to the Section Biosignal Processing)

Biomechanics and Motion Analysis, Second Edition

edited by

Christina Zong-Hao Ma

and

Hong Fu

submission deadline 30 Jun 2026 | Viewed by 299 | Submission Open

Keywords: biomechanics; motion capture and analysis; sports and rehabilitation engineering; artificial intelligence; assistive technology

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Biomechanics in Sport and Motion Analysis, 2nd Edition

edited by

Kamran Iqbal

submission deadline 30 Jun 2026 | Viewed by 295 | Submission Open

Keywords: biomechanics; sports science; human motion; artificial intelligence

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Scalable Statistical and Machine Learning Methods for Precision Health

edited by Xinyue Li, Kei Hang Katie Chan and Kaidi Xu

submission deadline 30 Jun 2026 | Viewed by 287 | Submission Open

Keywords: precision health; multimodal data; statistical learning; machine learning; scalable learning; computational efficiency; interpretability; generalizability; fairness and robustness; translational medicine

(This special issue belongs to the Section Biosignal Processing)

Innovative Bioengineering Platforms for Cancer Therapeutics: From Models to Screening

edited by

Eriko Katsuta

submission deadline 30 Jun 2026 | Viewed by 270 | Submission Open

Keywords: cancer drug screening; tumor microenvironment; 3D culture/organoids; microfluidics/organ-on-a-chip; AI-based drug discovery; bioinformatics and modeling; precision oncology; systems biology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Dental Stem Cells and Their Applications in Regenerative Medicine

edited by

Yuanyuan Han

and

Chengfei Zhang

submission deadline 30 Jun 2026 | Viewed by 256 | Submission Open

Keywords: dental stem cells; regenerative medicine; multilineage differentiation; tissue engineering

(This special issue belongs to the Section Regenerative Engineering)

Application of Intelligent Diagnosis and Decision Support in Biomedical Engineering

edited by

Voula Georgopoulos

and

Chrysostomos Stylios

submission deadline 30 Jun 2026 | Viewed by 250 | Submission Open

Keywords: clinical decision support; computational diagnostics; explainable artificial intelligence (XAI); healthcare technology; integrated diagnostic platforms; machine learning; predictive modeling; wearable technology

(This special issue belongs to the Section Biosignal Processing)

Nanoparticle-Based Drug Delivery Systems for Cancer Therapy

edited by Tianzhu Zhang and

Qiaoyu Liu

submission deadline 30 Jun 2026 | Viewed by 231 | Submission Open

Keywords: biomaterials; biomedical engineering; nanomedicines; drug delivery; cancer therapy

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Medical Imaging: Techniques, Applications, Impact and Innovations

edited by

Lina Karout

and Weiguo Li

submission deadline 30 Jun 2026 | Viewed by 230 | Submission Open

Keywords: radiology; CT; biomedical imaging processing; MRI; X-ray; biomedical imaging; computational radiology

(This special issue belongs to the Section Biosignal Processing)

Cardiovascular Bioprostheses

edited by

Mareike Barth

submission deadline 30 Jun 2026 | Viewed by 187 | Submission Open

Keywords: heart valve substitutes; vascular grafts; cardiovascular implants; in vitro models; computational approaches; biomechanics; tissue engineering; cardiovascular metabolism and degeneration

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Novel Microfluidics Applications in Dental, Oral, and Craniofacial Research

edited by

Xianrui Yang

, Jing Pan, Fan Zhang and

L. Shannon Holliday

submission deadline 3 Jul 2026 | Viewed by 297 | Submission Open

Keywords: dentistry; microfluidics; stem cells; bioengineering; biological mechanisms

Biomedical Applications of Optical Coherence Tomography, Third Edition

edited by Shintaro Horie

submission deadline 10 Jul 2026 | 1 articles | Viewed by 655 | Submission Open

Keywords: retinal imaging; optical coherence tomography; optics; biophotonics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Intelligent Medical Robots: Human–Machine Interaction and Medical Innovations

edited by

Kai Guo

and

Tingrui Pan

submission deadline 15 Jul 2026 | 1 articles | Viewed by 874 | Submission Open

Keywords: intelligent robotics; rehabilitation robotics; wearable robotics; human– machine interaction

(This special issue belongs to the Section Biosignal Processing)

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