Dental Stem Cells and Their Applications in Regenerative Medicine
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 5
Special Issue Editors
Interests: dental stem cells; regenerative medicine; tissue engineering; biomaterials
Special Issues, Collections and Topics in MDPI journals
Interests: pulp regeneration; dental stem cells; orthodontics; oral implant
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, “Dental Stem Cells and Their Applications in Regenerative Medicine”, provides a comprehensive overview of how dental stem cells are reshaping the landscape of regenerative medicine. Dental stem cells obtained from dental pulp, periodontal ligament, apical papilla, gingiva, and exfoliated deciduous teeth offer remarkable proliferative capacity, broad multilineage differentiation, and strong immunoregulatory functions. Their easy accessibility and minimal ethical constraints make them an exceptional cell source for regenerative strategies.
A major focus of this issue is the expanding potential of dental stem cells and their contribution to regenerative medicine at both the foundational and translational levels. This issue highlights new insights into the molecular and cellular mechanisms that support tissue repair, including the response of dental stem cells to inflammatory, mechanical, and biomaterial-derived cues. It also highlights advanced regenerative platforms that integrate these cells with engineered scaffolds, dynamic biomaterials, and cell-free therapeutic modalities such as extracellular vesicles.
Importantly, this issue aims to demonstrate that the regenerative potential of dental stem cells extends far beyond oral and craniofacial tissues. It seeks to present promising directions in neural restoration, skeletal regeneration, vascular repair, and the treatment of systemic disorders. Together, the contributions in this issue are expected to underscore the growing impact of dental stem cell research in driving innovation within regenerative medicine and highlight its future significance in clinical therapy.
Dr. Yuanyuan Han
Prof. Dr. Chengfei Zhang
Guest Editors
Manuscript Submission Information
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Keywords
- dental stem cells
- regenerative medicine
- multilineage differentiation
- tissue engineering
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