Biomaterial- and Engineering-Based Approaches for Organoids
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 12
Special Issue Editor
Interests: biopolymers; bioproducts and biorefining process engineering; rheology and phase transition of biopolymers; biobased adhesives and coatings; biodegradable plastics; structure and functional properties of biomacromolecules; biomaterials and hydrogels for environmental and medical uses
Special Issue Information
Dear Colleagues,
Organoids, three-dimensional multicellular structures that mimic the architecture and functionality of native tissues, have emerged as powerful tools in biomedical research, drug discovery, and regenerative medicine. The integration of biomaterial- and engineering-based approaches has significantly advanced the development and application of organoids. Biomaterials provide tailored microenvironments that mimic the extracellular matrix, enabling precise control over mechanical, chemical, and biological cues to guide organoid growth, differentiation, and functionality. Engineering techniques, such as microfabrication, 3D bioprinting, and microfluidics, further enhance the reproducibility, scalability, and physiological relevance of organoid systems. These technologies allow for the creation of complex, multicellular constructs with vascularization and spatial organization, bridging the gap between in vitro models and in vivo tissues. By combining biomaterial innovation with advanced engineering strategies, researchers can address current limitations in organoid culture, such as nutrient diffusion, maturation, and functional integration. This interdisciplinary approach holds immense potential for personalized medicine, disease modeling, and tissue engineering, paving the way for breakthroughs in understanding human development, pathology, and therapeutic interventions.
Prof. Dr. Xiuzhi Susan Sun
Guest Editor
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Keywords
- organoids
- biomaterials
- tissue engineering
- three-dimensional bioprinting
- microfluidics
- extracellular matrix
- disease modeling
- regenerative medicine
- personalized medicine
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