Managing Staphylococcus spp. Infections: Current Practices and Future Directions
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotic Therapy in Infectious Diseases".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 1205
Special Issue Editor
Special Issue Information
Dear Colleagues,
Staphylococcus aureus is often associated with varied clinical diseases. Infections caused by this pathogen can be community-acquired or associated with hospital settings. S. aureus can cause a range of clinical manifestations, varying from minor skin infections to life-threatening diseases such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome, and bacteremia. Coagulase-negative staphylococci (CNS), especially S. epidermidis and S. haemolyticus, although part of the normal skin flora, have emerged as opportunistic pathogens, particularly in immunocompromised patients and those with indwelling medical devices. S. lugdunensis has also emerged as a significant human pathogen, with distinct clinical and microbiological characteristics.
Several pathogenic factors associated with staphylococcal infections have been identified, including biofilm formation and toxin and adhesin production. Treatment remains challenging due to the emergence of multidrug-resistant strains. With the escalation of antibiotic resistance globally, the need for novel therapies, such as biofilm-disrupting agents, bacteriophages, phage-encoded enzymes, nanoparticle-based delivery systems, and monoclonal antibodies, is more crucial than ever.
This Special Issue focuses on current practices in managing staphylococcal infections, particularly focusing on novel approaches and future directions in the context of growing antibiotic resistance.
Dr. Nikolaos Giormezis
Guest Editor
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Keywords
- Staphylococcus aureus
- coagulase-negative staphylococci
- novel antibiotics
- novel therapies
- bacteriophages
- biofilm disruption
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