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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Design, Synthesis and Biological Evaluation of Antibacterial Compounds

edited by

Khondaker Miraz Rahman

submission deadline 15 Jun 2025 | 2 articles | Viewed by 4048 | Submission Open

Keywords: antibacterial agents; antifungal agents; antibiotics; antimicrobial resistance; drug discovery; medicinal chemistry

(This special issue belongs to the Section Novel Antimicrobial Agents)

Spread of Multidrug-Resistant Microorganisms, 2nd Edition

edited by

Mara Di Giulio

and

Silvia Di Lodovico

submission deadline 15 Jun 2025 | 1 articles | Viewed by 3126 | Submission Open

Keywords: multidrug-resistant organisms; MDR; antibiotic resistance gene; nosocomial infections; new marker of resistance

Antimicrobial Resistance in Biofilm-Associated Infections

edited by

Fazlurrahman Khan

Nazia Tabassum

and

Young-Mog Kim

submission deadline 15 Jun 2025 | 2 articles | Viewed by 2542 | Submission Open

Keywords: biofilms; antimicrobial resistance; chronic infections; biofilm matrix; virulence factors; antibiotic efficacy; pathogen persistence; biofilm formation; medical implants; quorum sensing

(This special issue belongs to the Section Antibiofilm Strategies)

Antimicrobial Strategies against Oral Pathogenic Bacteria and Biofilm, 2nd Edition

edited by

María C. Sánchez Beltrán

submission deadline 20 Jun 2025 | 3 articles | Viewed by 8651 | Submission Open

Keywords: oral biofilms; oral pathogenic bacteria; oral infections; antimicrobial strategies; microbial oral homeostasis; oral dysbiosis; antibiotic resistance

(This special issue belongs to the Section Antibiofilm Strategies)

Antimicrobial Stewardship and Infection Prevention in Intensive Care Unit

edited by Mihai Sava and

Majdi N. Al-Hasan

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1986 | Submission Open

Keywords: antimicrobial stewardship; infection prevention; intensive care unit (ICU); antimicrobial resistance; healthcare-associated infections; patient safety

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Global Strategies for Antimicrobial Stewardship: Insights from WHO and PAHO

edited by

Gustavo Horacio Marin

and Gabriel Levy-Hara

submission deadline 20 Jun 2025 | Viewed by 256 | Submission Open

Keywords: antimicrobial; stewardship; resistance; consumption; use

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Diagnosis and Treatment of Drug-Resistant Mycobacterium tuberculosis

edited by Alberto Matteelli and Aditi Deshpande

submission deadline 25 Jun 2025 | 1 articles | Viewed by 2651 | Submission Open

Keywords: tuberculosis; multidrug-resistant tuberculosis; research; diagnostic tests; drugs; treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance Genes: Spread and Evolution

edited by

Angeliki Mavroidi

and

Georgia Vrioni

submission deadline 29 Jun 2025 | 7 articles | Viewed by 12860 | Submission Open

Keywords: microbes; antimicrobial resistance; resistance genes; gene flow; evolution

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Natural Products and Bio-Nanomaterials: Novel Strategies to Overcome Antibiotic Resistance

edited by

Renata Katsuko Takayama Kobayashi

, Gerson Nakazato and

Sara Scandorieiro

submission deadline 30 Jun 2025 | 9 articles | Viewed by 31120 | Submission Open

Keywords: nanotechnology; material; antimicrobial; nature; resistance; nanoparticles; strategy

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Resistance and Therapy in Intensive Care Unit

edited by

Pablo Vidal-Cortés

, Borja Suberviola and

David Andaluz-Ojeda

submission deadline 30 Jun 2025 | 9 articles | Viewed by 27131 | Submission Open

Keywords: ICU; sepsis; antimicrobial; multidrug-resistant bacteria; sepsis; antimicrobial stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Computational Approaches in Discovery and Design of Antimicrobial Peptides—2nd Edition

edited by

Guillermin Agüero-Chapin

Yovani Marrero-Ponce

and

Agostinho Antunes

submission deadline 30 Jun 2025 | 6 articles | Viewed by 20055 | Submission Open

Keywords: rational search and design of AMPs; alignment-based and alignment-free approaches; machine-learning; artificial intelligence; biodiscovery with associated computational analyses/tools; non-conventional in silico approaches

(This special issue belongs to the Section Antimicrobial Peptides)

Optimizing Antimicrobial Use: Antimicrobial Stewardship and Surveillance

edited by Jesus Ruiz-Ramos

submission deadline 30 Jun 2025 | 6 articles | Viewed by 16266 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial cycling; antimicrobial resistance; decision support; antibiotic optimization; antibiotic therapy

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Combination Therapy against Multidrug-Resistant Pathogens

edited by

Mao Hagihara

and

Hideo Kato

submission deadline 30 Jun 2025 | 5 articles | Viewed by 14902 | Submission Open

Keywords: combination therapy; multidrug-resistant pathogens; in vitro; in vivo; clinical study; pharmacokinetics; pharmacodynamics.

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Natural Peptides from Arthropods, Amphibians, and Reptiles to Combat Conventional Antibiotic Resistance

edited by

Christopher Shaw

Tianbao Chen

and

Lei Wang

submission deadline 30 Jun 2025 | 3 articles | Viewed by 10663 | Submission Open

Keywords: antimicrobial peptide; peptide modification; antibiotic resistance; structure– activity relationship; membrane selectivity; resistant strains

(This special issue belongs to the Section Antimicrobial Peptides)

Antimicrobial Resistance and Infections in Veterinary Settings

edited by Hatem Kittana and Tamara Gull

submission deadline 30 Jun 2025 | 2 articles | Viewed by 9767 | Submission Open

Keywords: veterinary medicine; antibiotics; antimicrobial resistance; infectious microorganims; food-producing animals; companion aniamls

(This special issue belongs to the Section Antibiotics in Animal Health)

Inappropriate Use of Antibiotics in Pediatrics

edited by Brian R. Lee

submission deadline 30 Jun 2025 | 3 articles | Viewed by 6537 | Submission Open

Keywords: antimicrobial stewardship; inappropriate antibiotic prescription; antimicrobial resistance; pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Clinical Pharmacokinetics, Pharmacodynamics, and/or TDM of Antimicrobial Agents

edited by

Yukihiro Hamada

submission deadline 30 Jun 2025 | 4 articles | Viewed by 5641 | Submission Open

Keywords: pharmacokinetics/pharmacodynamics; therapeutic drug monitoring; antimicrobial resistant; AI; antimicrobial stewardship

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Development of Antimicrobial Peptides from Amphibian, 2nd Edition

edited by

Maria Luisa Mangoni

Bruno Casciaro

and Maria Rosa Loffredo

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5457 | Submission Open

Keywords: frog skin-derived antimicrobial peptides; natural and synthetic AMPs; the synergy of AMPs; insights into the mechanism(s) of action of AMPs; drug delivery system

(This special issue belongs to the Section Antimicrobial Peptides)

Antimicrobial Stewardship and Optimizing Antibiotic Dose in Critically Ill Patients

edited by Barbara J. Philips

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5080 | Submission Open

Keywords: antibiotics; antimicrobials; intensive care; critical care; sepsis; pharmacokinetics; pharmacodynamics; stewardship; beta-lactams; aminoglycosides; quinolones; cephalosporins; antifungal

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Advances in the Discovery of Novel Antimicrobial Agents in Nature and Their Applications, 2nd edition

edited by

Ana Tomić

and

Olja Šovljanski

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4804 | Submission Open

Keywords: antimicrobial agents; antimicrobial mechanisms; natural products

(This special issue belongs to the Section Biosynthesis and Combinatorial Approaches in Antimicrobial Discovery)

Antibiotics Stewardship in Low and Middle-Income Countries

edited by

Tania Ayllón

and

Gustavo Ortiz-Díez

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3441 | Submission Open

Keywords: antimicrobial resistance (AMR); low and middle-income countries (LMICs); multidrug-resistant (MDR) strains; One Health; public health; animal health; environmental impact; healthcare; sanitation and hygiene; preventive medine; epidemiological surveillance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Irrational Antibiotic Use in Primary Care

edited by

Xiaodong Guan

, Luwen Shi and Paul Little

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3278 | Submission Open

Keywords: irrational antibiotic use; antimicrobial resistance; drivers; primary care

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

New Insights into Prevention, Diagnosis, and Treatment of Neonatal Sepsis and Short- and Long-Term Outcomes

edited by

Vasilios Giapros

Dimitrios Rallis

and Maria Baltogianni

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3083 | Submission Open

Keywords: neonate; sepsis; early sepsis; late sepsis; antibiotic resistance; multiple resistance antibiotics; antibiotics stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Prevention and Antimicrobial Surveillance of Hospital-Associated Infections

edited by Theodouli Stergiopoulou

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2769 | Submission Open

Keywords: infection monitoring; surveillance program; antimicrobial surveillance; healthcare-associated infections

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Microbial Biofilms: Identification, Resistance and Novel Drugs

edited by

Célia Fortuna Rodrigues

and

Susana Patrícia Lopes

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2559 | Submission Open

Keywords: biofilm; resistance; pathogens; alternative treatment; plant extract; peptides; nanotechnology

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotics Use for Respiratory Diseases

edited by

Mirela Loredana Grigoraş

Cristian Oancea

and

Cosmin Citu

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2383 | Submission Open

Keywords: antimicrobial resistance; respiratory diseases; diagnostics; co-infection; healthcare-associated infection

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options

edited by Novella Carannante

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2284 | Submission Open

Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A One Health Approach to Antimicrobial Resistance, 2nd Edition

edited by

Beatriz Robredo

submission deadline 30 Jun 2025 | 3 articles | Viewed by 2099 | Submission Open

Keywords: One Health; antibiotic; antimicrobial resistance; animal; food; environment

Antimicrobial Activities of Bioactive Components from Honeybee Products

edited by

Otilia Bobis

Adriana Cristina Urcan

and

Claudia Pașca

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1887 | Submission Open

Keywords: bee products; antibiotics; antimicrobial activity; bioactive compounds; honey; propolis; bee pollen/beebread; royal jelly; bee venom; microbial resistance

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Therapy in Respiratory Tract Infections (RTIs)

edited by Ágnes Tóth and

Attila Csaba Nagy

submission deadline 30 Jun 2025 | Viewed by 552 | Submission Open

Keywords: antibiotic therapy; respiratory tract infections; clinical guidelines; prescribing practices; antibacterial resistance; antimicrobial stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Clinical Pharmacology and Pharmacy of Antimicrobial Agents, 2nd Edition

edited by

Ana D. Tomas Petrović

submission deadline 30 Jun 2025 | Viewed by 339 | Submission Open

Keywords: antibiotics; antifungals; antiviral agents; antiparasitic agents; pharmacology; pharmacy; pharmacoepidemiology; drug utilization research; pharmacodynamics; pharmacokinetics; toxicology; interactions; drug combinations; repositioning; synergism

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Dermatological Infections and Antibiotic Treatment

edited by

Oriana Simonetti

submission deadline 30 Jun 2025 | Viewed by 331 | Submission Open

Keywords: dermatological infections; antibiotic resistance; antibiotics; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A Themed Issue in Honor of Dr. Lynne V. McFarland—Clostridioides difficile Infection and Impact of Antibiotics on the Intestinal Microbiome

edited by Ellie J. C. Goldstein and Shan Goh

submission deadline 30 Jun 2025 | Viewed by 330 | Submission Open

Keywords: Clostridioides difficile infections; intestinal microbiome; infection control practices; antibiotic complications; probiotics; live biotherapeutic products; treatment; prevention

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial and Antioxidant Efficacy of Essential Oils

edited by

Mijat Božović

submission deadline 30 Jun 2025 | Viewed by 320 | Submission Open

Keywords: essential oils; chemical analysis; extraction methods; antimicrobial activity; antioxidant potential

(This special issue belongs to the Section Plant-Derived Antibiotics)

Recent Advances in Efflux Pump Inhibitors and Their Role in Combatting Multidrug Resistance

edited by

László Orosz

and

Spengler Gabriella

submission deadline 30 Jun 2025 | Viewed by 316 | Submission Open

Keywords: multidrug resistance; multidrug efflux pump; efflux pump inhibitor (EPI); accumulation assay; efflux assay; fluorochromes; ethidium bromide; quorum sensing; biofilm

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Bacterial Infections and Global Health: The Escalating Threat of Antibiotic Resistance

edited by

Nicola Petrosillo

and

Guido Granata

submission deadline 30 Jun 2025 | Viewed by 309 | Submission Open

Keywords: infection control; antimicrobial stewardship; spread of multidrug-resistant bacteria; methicillin-resistant Staphylococcus aureus; carbapenemases; metallo-β -Lactamase; microbiology diagnostics in field hospitals; One Health

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A Themed Issue in Honor of Prof. Dr. Fausto Catena—Outstanding Contributions in the Fields of Antibiotics in the Acute Care and Emergency

edited by Carlo Vallicelli

submission deadline 30 Jun 2025 | Viewed by 240 | Submission Open

Keywords: emergency surgery; intra-abdominal infections; antibiotic treatment; trauma surgery; sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Drivers of Virulence and Antimicrobial Resistance in Emerging and Re-Emerging Pathogens

edited by

Ons Bouchami

Opeyemi Lawal

and Ingrid Maria Cecilia Rubin

submission deadline 30 Jun 2025 | Viewed by 206 | Submission Open

Keywords: AMR; microbial pathogenesis; microbial ecology; pathogen dynamics; genomic epidemiology; multiomics; microbial interactions; AI/ML

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

Antibiotic Resistance and Virulence in Bacterial Isolates: A Genomic Perspective from Human and Animal Sources

edited by

Sónia Ramos

and

Alexandra Nunes

submission deadline 30 Jun 2025 | Viewed by 201 | Submission Open

Keywords: MDRB; antimicrobial resistance; one health; mobile genetic elements; AMR; antimicrobial resistance gene

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Membrane Disruptors: The Role of Antimicrobial Peptides in Combatting Pathogens

edited by

Andrea Mescola

submission deadline 30 Jun 2025 | Viewed by 181 | Submission Open

Keywords: antimicrobial peptides (AMPs); microbial resistance; drug-resistant pathogens; anticancer; antiviral; membrane disruption; membrane poration; permeabilization; lipids; peptide design and engineering

(This special issue belongs to the Section Antimicrobial Peptides)

Antimicrobial Extracts and Compounds Derived from Plants

edited by

Giovanna Simonetti

submission deadline 30 Jun 2025 | Viewed by 174 | Submission Open

Keywords: antibacterial; antifungal; plant extract; plant compounds; antibiotic-resistant strains; virulence factors; synergistic interactions

(This special issue belongs to the Section Plant-Derived Antibiotics)

Periodontal Bacteria and Periodontitis: Infections and Therapy

edited by Anna Skurska

submission deadline 30 Jun 2025 | Viewed by 125 | Submission Open

Keywords: periodontitis; infection; antibiotics; antibacterial activities

(This special issue belongs to the Section Antibiofilm Strategies)

Antimicrobial Stewardship in the Management of Bloodstream Infections

edited by

Zoran Todorovic

Gordana Dragović

and Saša Trailović

submission deadline 1 Jul 2025 | Viewed by 220 | Submission Open

Keywords: bloodstream infections; antimicrobial drugs; immunodeficiency; sepsis; antimicrobial resistance; therapeutic drug monitoring

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Therapy in Oral Diseases

edited by

Alexandra Roman

and

Andrada Soanca

submission deadline 5 Jul 2025 | 3 articles | Viewed by 9026 | Submission Open

Keywords: oral; antibiotic; antiseptic; tooth; periodontium; dental caries; implant; healing; cell; biomaterials; periodontitis; biocompatibility; toxicity; periodontology; periodontal pocket; bacteria; nonsurgical treatment; oral surgery; clinical trial

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology, Clinical Microbiology and Antimicrobial Therapy: A Shared Effort against Infectious Diseases

edited by Francesca Pica

submission deadline 15 Jul 2025 | 10 articles | Viewed by 17801 | Submission Open

Keywords: microbes and antimicrobials; bacteria; fungi and viruses; antibiotics; antifungals and antivirals; antimicrobial resistance; rapid diagnostics; genotypic and phenotypic resistance; epidemiology; public health; infectious diseases; hospital-acquired infections (HAIs); community infections; natural and synthetic antimicrobial compounds

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology, Diagnosis and Antimicrobial Treatment of Hospital-Acquired Infections

edited by

Diamantis Kofteridis

and

Petros Ioannou

submission deadline 15 Jul 2025 | 4 articles | Viewed by 5065 | Submission Open

Keywords: hospital-acquired infection; bacteremia; bloodstream infection; pneumonia; ventilator-associated pneumonia; urinary tract infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Impact of Plant-Derived Products as Novel Antimicrobial Agents

edited by Eleonora Spinozzi

submission deadline 15 Jul 2025 | Viewed by 149 | Submission Open

Keywords: natural compounds; plant bacteria; fungal infections; antimicrobial

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Activity of Bioactive Peptides and Their Derivatives

edited by Alexandro Rodríguez-Rojas

submission deadline 20 Jul 2025 | 7 articles | Viewed by 9871 | Submission Open

Keywords: antimicrobial resistance (AMR); global health threat; novel antimicrobial agents; bioactive peptides (AMPs); natural antimicrobial agents; broad-spectrum activity; antimicrobial activity; mechanisms of action; structure– activity relationships; AMP-based therapeutics; clinical applications of AMPs; combinatory therapy

(This special issue belongs to the Section Antimicrobial Peptides)

Plant Extracts and Natural Products for the Control of Animal Pathogens in a ONE-Health Perspective

edited by Ernesto Palma,

Roberto Bava

and Carmine Lupia

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1099 | Submission Open

Keywords: natural products; essential oils; hive products; colostrum; pets; livestock; drug resistances; antimicrobial resistances; sustainable pathogen control; animal health and welfare

(This special issue belongs to the Section Antibiotics in Animal Health)

Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance

edited by

Luisa Brito

and

Acacio Salamandane

submission deadline 20 Jul 2025 | Viewed by 210 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health

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