- Article
Background and Objectives: The nomenclature of calcium pyrophosphate deposition (CPPD) disease remains confusing, with different labels used interchangeably to describe the disease. Although ‘CPPD disease’ is the term that has been recomm...
2026 September - 6 articles
Background and Objectives: The nomenclature of calcium pyrophosphate deposition (CPPD) disease remains confusing, with different labels used interchangeably to describe the disease. Although ‘CPPD disease’ is the term that has been recomm...
Humans and other great apes are unique among animals in lacking functional uricase, an enzyme that breaks down urate and allows its excretion. Modern-day humans have elevated serum urate, which is associated with various chronic health issues, includ...
Gout is one of the most common inflammatory arthritides worldwide, and its burden is rising in Southeast Asia alongside rapid demographic and socioeconomic transitions. This region, characterized by diverse healthcare systems, cultural practices, and...
Gout is a systemic metabolic inflammatory disease driven by hyperuricemia and monosodium urate crystal deposition, and is frequently accompanied by chronic kidney disease and uric acid nephrolithiasis. Current evidence indicates that acidic urine, hy...
Background and Objectives: Despite evidence demonstrating the advantages of rheumatology-led point-of-care (POC) polarised light microscopy (PLM), it remains underutilised in many hospital settings. We aimed to identify barriers to its use and assess...
Calcific tendinitis (CT) is a condition that most commonly affects the rotator cuff tendons of the shoulder joint. Fundamental crystal morphology and composition underlying different radiological stages of CT remained insufficiently characterized. We...