IECBM 2022 - 34 articles
Online | 1–15 November 2022
Volume Editor:
Vladimir Uversky, University of South Florida, USA
One of the hot topics in medical research involves using new materials for repairing human tissues. Graphene and its derivatives (which will be abbreviated as “graphene” in the following text for the sake of simplicity) happens to be one...
Background—TC, LA and MCM plants(family: Cucurbitaceae) are widely used in traditional medicine and are important sources of vegetables in the world [...]
Since December 2019, the problem caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has grown into a global threat. The search for new treatment strategies is strongly associated with both fundamental research into the mechanisms...
Cell spheroids represent a scaffold-free route to form cell aggregates through maximizing cell-cell interactions. Spheroids have gained significant attention for the engineering of multilayer tissues as they offer a closer resemblance of physiologica...
Preeclampsia (PE) is one of the most common complications of pregnancy that occurs in 3–8% of pregnant women, being one of the top five causes of maternal morbidity and mortality. We found that PE-associated polymorphisms near the FLT1 gene are...
Research in nanostructured materials has led to the development of different applications of relevance in the fields of medicine and biomedical engineering. In this regard, the field of drug delivery has probably benefited the most due to the possibi...
Ab initio DNA synthesis refers to the unusual synthesis of dsDNA (with a length ranging from tens of bp to kbp) by thermophilic DNA polymerases from free dNTPs in the complete absence of added DNAs. As commonly believed, the reaction product is a lin...
Telomeres are important specialized nucleoprotein structures at the ends of linear eukaryotic chromosomes involved in protecting DNA from damage. The functional characteristic of telomeres is the length. Changes in telomere structure is of enormous e...
Aptamers are nucleic acid ligands which exhibit specific binding to a desired target. Oligonucleotides are limited in their ability to form hydrophobic interactions. The affinity of aptamers can be improved with the introduction of hydrophobic modifi...
Cutaneous administration has advantages over the oral or intravenous route, such as convenience for the patient, avoiding hepatic metabolism, and providing sustained administration of the active component over long periods of time. A major challenge...
Identification of proteins has received considerable attention in recent years due to the increasing interest in resolving individual biomolecules under physiologically relevant conditions [...]
The aim of this research was to analyze the neuroprotective action of drugs via an evidence-based approach to analyzing the expression of endogenous neuroprotection factors in various experimental models of cerebral ischemia in Wistar white rats (int...
Skin burns are injuries of different degrees of complexity (first to third) caused by physical and/or chemical trauma. There is a necessity to improve the rapid retrieval of superficial wounds (first grade) to enhance epithelization, avoiding dehydra...
Papain-like cysteine proteases (PLCPs) are widely expressed enzymes, the main function of which is low-specific-protein turnover in the acidic conditions of lysosomes. Additionally, these proteases provide specific functions in other compartments suc...
Wound healing in adult mammals results in scar formation, which prevents recovering the full functionality of the original skin. This area of dermatology is constantly evolving and especially focuses on aging and the design of recovery treatments for...
Selenium in the human body exhibits strong antioxidant and immunomodulatory properties. This bio-element is found in the active centers of antioxidant enzymes, which participate in the elimination of damage caused by free oxygen radicals. It enters i...
Liposomal supramolecular strustures (SMS) are widespread in different areas of modern science [...]
In this study, Hausa potato starch was subjected to single and dual modifications by HMT and citric acid. The parameters such as relative crystallinity, pasting, functional properties, and in vitro digestibility were studied. The XRD analysis showed...
The talipot palm (Corypha umbraculifera L.) is an unconventional source of stem starch, with a 76% starch yield. Talipot starch was cross-linked with epichlorohydrin (EPS) and phosphoric acid (PS), which significantly altered the functional, pasting,...
Lavandula angustifolia is a medicinal plant with important benefits for the human body, exhibiting antimicrobial and antioxidants activities. Scientific data has detailed the fact that lavender extract presented favorable characteristics to health, s...
The development of the NSAID family has represented a excitingapproach in the treatment of inflammatory disorders, such as arthritis, and for the management of acute pain, in relation to the well-known traditional Non-Steroidal Anti-Inflammatory Drug...
Films and coatings fabricated with renewable biopolymers and antimicrobial agents have attracted research interest owing to their contribution to food safety and biodegradability. The study aimed to determine the effect of natural plant extracts from...
Genome-wide association studies (GWAS) have identified that one of the autoimmune disease-associated loci, predisposing for the development of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) and Systemic Sclerosis (SSc), is the rs356774...
Protein purification is an ever-vital technique for academia and industry. This paper mainly reviews and discusses one of the core components of proteomics—the latest advances in separation technology for protein components—focusing on fi...
Combinations of anticancer chemotherapeutics with glucocorticoids (GCs) are usually used to broaden the therapeutic range of main cytostatic agents and to diminish the side effects of chemotherapy. However, long-term GC administration leads to tumor...
The goal of gene therapy is to treat diseases through gene editing and modification of gene expression. Viral vectors, antisense oligonucleotides (ASO) and RNA interference (RNAi) are some of the gene therapies under development. DNAzymes, or deoxyri...
This study investigated the changes in the physicochemical properties of maize starch on nixtamalized flours produced with ohmic heating (OH). Samples were prepared using the following OH process variables and levels: cooking temperature (85 and 90 &...
Membrane-based gas separation is an important unit operation in chemical industries due to its simplicity, ease of operation, reduced energy consumption, and compact structure. For gas separation, novel studies were carried out by synthesising enzyme...
A comprehensive study of the structure, properties and biological functionality of salt chitosan complexes with L- and D-aspartic acid (AspA) was carried out. It has been established that these polymer salts differ in their spatial organization, chir...
The recycling of food and agricultural waste, which is released as a result of domestic and agricultural uses, instead of throwing them into the garbage cycle and the environment, is of great importance both for the protection of the environment and...
Peripheral arterial disease (PAD) is characterized by stenosis and occlusion of the arteries leading to poor blood supply to the limb. Patients with PAD suffer pain at rest, intermittent claudication, skin ulcers, and gangrene. The end-stage of the d...
Multidrug-resistant bacteria can lead to skin wound infections, pain and long-term treatment. The development of high-performance dressings for the treatment of infected skin wounds represents a necessary requirement. In this paper it was designed an...
The present study aimed to evaluate in vitro enzymatic activity of a novel biotechnological active complex based on natural origin compounds—thermophilic lipase and β-cyclodextrin—for hydrolysis of acylglycerides in plant oils and fa...
The variety of spectral properties of visual pigments is provided mainly by the amino acid sequences of their protein component, the so-called visual opsins. However, such data on these proteins of gastropod mollusks are very scarce, and for terrestr...
