Abstract
A comprehensive study of the structure, properties and biological functionality of salt chitosan complexes with L- and D-aspartic acid (AspA) was carried out. It has been established that these polymer salts differ in their spatial organization, chirooptic characteristics, surface charge and macrocoil size. In experiments in vitro on a wide range of biological objects (unicellular algae, planktonic crustaceans, aerobic bacterial microorganisms, cell cultures and test plants), it was found that the chitosan salt with D-AspA exhibited the best biological activity. The results obtained confirm our hypothesis that the biological homochiral hierarchy principles are most consistent with the chitosan (D-aminoglycan) derivatives with the D-antipode of the acid.
Supplementary Materials
The presentation material of this work is available online at https://www.mdpi.com/article/10.3390/IECBM2022-13399/s1.
Author Contributions
Conceptualization, A.S. and N.G.; methodology, N.G. and I.Z.; investigation, N.G., X.S., O.U., T.L. and I.Z.; data curation, O.U., T.L. and I.Z.; writing—original draft preparation, N.G.; writing—review and editing, A.S.; visualization, N.G. and X.S.; supervision, A.S.; project administration, A.S.; funding acquisition, A.S. All authors have read and agreed to the published version of the manuscript.
Funding
The study was supported by a grant from the Russian Science Foundation № 22-23-00320, https://rscf.ru/project/22-23-00320/.
Institutional Review Board Statement
Not applicable.
Informed Consent Statement
Not applicable.
Data Availability Statement
Not applicable.
Conflicts of Interest
The authors declare no conflict of interest.
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