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Surgeries, Volume 6, Issue 3 (September 2025) – 10 articles

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17 pages, 4741 KiB  
Systematic Review
Venous Malformation of the Maxilla: A Systematic Review and a Report of an Unusual Case
by Alexandre Perez, Elena Pierantozzi, Anaël Jose Cancela, Valerio Cimini and Tommaso Lombardi
Surgeries 2025, 6(3), 56; https://doi.org/10.3390/surgeries6030056 - 11 Jul 2025
Abstract
Background: Venous malformation, formerly designated as cavernous hemangioma, is a rare vascular lesion characterized by significant endothelial cells proliferation, predominantly affecting young females. Diagnosis is challenging due to its low incidence and variety of clinical, radiological, and histological presentations. Objectives: The aim was [...] Read more.
Background: Venous malformation, formerly designated as cavernous hemangioma, is a rare vascular lesion characterized by significant endothelial cells proliferation, predominantly affecting young females. Diagnosis is challenging due to its low incidence and variety of clinical, radiological, and histological presentations. Objectives: The aim was to review the current scientific understanding of maxillary venous malformation based on the available literature and present an additional rare case of venous malformation of the upper maxilla. Methods: A systematic review was conducted across PubMed, Google Scholar, and Embase databases for studies published between January 1990 and April 2025. Inclusion criteria encompassed meta-analyses, systematic reviews, randomized controlled trials, non-randomized controlled trials, cohort studies, and case reports describing cavernous hemangiomas and venous malformation of the maxilla. All clinical and radiological characteristics were considered. Results: Out of 10,021 studies identified through our database search, 22 met the inclusion criteria, describing 28 (29 with our case) clinical cases of maxillary venous malformation. Conclusions: Maxillary venous malformation presents complex and varied clinical and radiological aspects, which are crucial for preoperative assessment and management. Appropriate measures may be necessary to prevent bleeding complications during lesion removal. To the best of our knowledge, this is the first comprehensive review on venous malformation of the maxilla. In addition, we report an unusual case identified incidentally during implant planning and successfully removed through isolated bone augmentation. Full article
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14 pages, 273 KiB  
Review
Artificial Intelligence Tools in Surgical Research: A Narrative Review of Current Applications and Ethical Challenges
by Bryan Lim, Ishith Seth, Jevan Cevik, Xin Mu, Foti Sofiadellis, Roberto Cuomo and Warren M. Rozen
Surgeries 2025, 6(3), 55; https://doi.org/10.3390/surgeries6030055 - 9 Jul 2025
Viewed by 75
Abstract
Background/Objectives: Artificial intelligence (AI) holds great potential to reshape the academic paradigm. They can process large volumes of information, assist in academic literature reviews, and augment the overall quality of scientific discourse. This narrative review examines the application of various AI tools in [...] Read more.
Background/Objectives: Artificial intelligence (AI) holds great potential to reshape the academic paradigm. They can process large volumes of information, assist in academic literature reviews, and augment the overall quality of scientific discourse. This narrative review examines the application of various AI tools in surgical research, its present capabilities, future directions, and potential challenges. Methods: A search was performed by two independent authors for relevant studies on PubMed, Cochrane Library, Web of Science, and EMBASE databases from January 1901 until March 2025. Studies were included if they were written in English and discussed the use of AI tools in surgical research. They were excluded if they were not in English and discussed the use of AI tools in medical research. Results: Forty-two articles were included in this review. The findings underscore a range of AI tools such as writing enhancers, LLMs, search engine optimizers, image interpreters and generators, content organization and search systems, and audio analysis tools, along with their influence on medical research. Despite the multitude of benefits presented by AI tools, risks such as data security, inherent biases, accuracy, and ethical dilemmas are of concern and warrant attention. Conclusions: AI could offer significant contributions to medical research in the form of superior data analysis, predictive abilities, personalized treatment strategies, enhanced diagnostic accuracy, amplified research, educational, and publication processes. However, to unlock the full potential of AI in surgical research, we must institute robust frameworks and ethical guidelines. Full article
19 pages, 1102 KiB  
Article
Can Better Surgical Education Lead to the Improved Acquisition of Young Trauma Surgeons? A Prospective Survey of Medical Students Concerning the Impact of Teaching Quality on the Future Choice of Medical Discipline
by Annalena Göttsche, Marcus Vollmer, Richard Kasch, Lyubomir Haralambiev, Axel Ekkernkamp and Mustafa Sinan Bakir
Surgeries 2025, 6(3), 54; https://doi.org/10.3390/surgeries6030054 - 8 Jul 2025
Viewed by 167
Abstract
Introduction: The escalating scarcity of skilled healthcare professionals is particularly pronounced within surgical specialties, where the prospect of attracting prospective medical practitioners poses formidable challenges. Throughout their academic journey, students exhibit diminishing enthusiasm and motivation to pursue careers in surgery, including trauma surgery. [...] Read more.
Introduction: The escalating scarcity of skilled healthcare professionals is particularly pronounced within surgical specialties, where the prospect of attracting prospective medical practitioners poses formidable challenges. Throughout their academic journey, students exhibit diminishing enthusiasm and motivation to pursue careers in surgery, including trauma surgery. It is postulated that the caliber of teaching plays a pivotal role in influencing students’ subsequent specialization choices. Methods: This prospective observational study was conducted among a cohort of third-year medical students at the German University Medicine Greifswald. The methodology encompassed the utilization of a self-administered questionnaire to procure data. Results: The study encompassed 177 participants, of whom 34.7% expressed an inclination toward a career in surgery (22.7% in trauma surgery). Participants who reported a favorable impact from the examination course displayed a significantly heightened interest in clinical clerkships within trauma surgery (p < 0.001), and even expressed a contemplation of specializing in orthopedics and trauma surgery (p = 0.001). Logistic regression analysis highlighted that the convergence of practical training and positive role modeling emerged as the most influential factors augmenting the allure of trauma surgery. Conclusions: Evidently, students who gleaned substantial benefits from high-quality practical instruction in trauma surgery exhibited a significantly heightened likelihood of pursuing this domain in their future endeavors. Surgical academic institutions stand to leverage this insight in their strategic planning for attracting and retaining potential residents. Cultivating a positive affinity for trauma surgery should be instilled early in the curriculum, subsequently sustained through ongoing immersive engagement that encompasses professional as well as interpersonal dimensions. Full article
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14 pages, 2414 KiB  
Review
Large Submandibular Duct Sialolith Removal Using a Diode Laser: Description of the Technique Based on Two Cases and Narrative Review of the Literature
by Giuseppe D’Albis, Marta Forte, Alfonso Manfuso, Alexandra Artin, Mariachiara Fioriello, Adriano Di Grigoli, Luisa Limongelli and Saverio Capodiferro
Surgeries 2025, 6(3), 53; https://doi.org/10.3390/surgeries6030053 - 7 Jul 2025
Viewed by 152
Abstract
Background/Objectives: The introduction of innovative technologies for the management of oral diseases has revolutionized treatment approaches, offering less invasive options and improved outcomes. Among oral cavity diseases, sialolithiasis is the most common disorder of the salivary glands. It involves the formation of [...] Read more.
Background/Objectives: The introduction of innovative technologies for the management of oral diseases has revolutionized treatment approaches, offering less invasive options and improved outcomes. Among oral cavity diseases, sialolithiasis is the most common disorder of the salivary glands. It involves the formation of calculi or stones within the salivary ducts, primarily affecting the submandibular gland due to its tortuous duct and the alkaline nature of its saliva. In particular, laser-assisted techniques have shown significant promise in enhancing the precision and safety in the management of sialolith removal. This article aims to present a case report and also explores the scientific evidence supporting these innovative methods, highlighting their benefits and limitations in clinical practice. Methods: This research was conducted using PubMed and Scopus search engines with a combination of relevant keywords, including laser, laser-assisted, laser treatment in combination with sialolith, sialolith removal, and sialoadenectomy. Selected articles were carefully reviewed to identify studies reporting data on the effectiveness of laser-assisted sialolith removal. Results: Results from the literature review indicate a growing interest in the application of diode laser and CO2, with evidence suggesting improved clinical outcomes and reduced postoperative pain compared to traditional methods. Conclusions: Although lasers offer enhanced safety and reduced morbidity and bleeding, which ensures optimal visibility, certain limitations must be considered, including the need for an adequate training period. Further randomized clinical trials and longer follow-up studies are needed to better evaluate their use in sialolith removal. Full article
(This article belongs to the Special Issue Oral Laser Surgery: Current Evidences and Perspectives)
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10 pages, 894 KiB  
Article
High Fusion Rates with Structured Titanium TLIF Cages: A Retrospective 1-Year Study with and Without Adjacent Level Dynamic Stabilization
by Sonja Häckel, Jessica Gaff, Alana Celenza, Gregory Cunningham, Michael Kern, Paul Taylor and Andrew Miles
Surgeries 2025, 6(3), 52; https://doi.org/10.3390/surgeries6030052 - 30 Jun 2025
Viewed by 248
Abstract
Background: Structured titanium (ST) cages are designed to enhance osseointegration and fusion in lumbar interbody procedures. However, clinical and radiological outcomes following TLIF using ST cages—particularly with or without adjacent-level dynamic stabilization (DSS)—have not been widely reported. Objective: To evaluate 12-month [...] Read more.
Background: Structured titanium (ST) cages are designed to enhance osseointegration and fusion in lumbar interbody procedures. However, clinical and radiological outcomes following TLIF using ST cages—particularly with or without adjacent-level dynamic stabilization (DSS)—have not been widely reported. Objective: To evaluate 12-month fusion outcomes and patient-reported outcomes (PROMs) after TLIF with structured titanium cages, comparing cases with and without adjacent-level DSS. Methods: In this retrospective cohort study, 82 patients undergoing TLIF with ST cages were analyzed—41 with hybrid instrumentation (TLIF + DSS) and 41 with TLIF alone. PROMs (ODI, VAS for back and leg pain, EQ-5D-5L) were assessed preoperatively and at 12 months. Fusion was assessed via CT scans at 12 months. Results: PROMs significantly improved over time in both groups (p < 0.001 for ODI, VAS back, VAS leg), but there were no significant differences between the hybrid and non-hybrid groups. Overall, the interbody fusion rate was 84%. Complete fusion was observed in 84% of the hybrid group and 80% of the TLIF-only group (p = 0.716), with very low rates of non-union. Conclusions: Structured titanium cages demonstrated excellent 1-year fusion rates and supported significant clinical improvement after TLIF. The addition of dynamic stabilization had no measurable effect on patient-reported or radiological outcomes at 12 months. Long-term studies are needed to assess any potential effect of DSS on adjacent segment disease. Full article
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11 pages, 2507 KiB  
Article
Drawing the Surgical Blueprint: Evaluating ChatGPT Versus Gemini Across Diverse Plastic Aesthetic Procedures
by Gianluca Marcaccini, Ishith Seth, Omar Shadid, Roberto Cuomo and Warren M. Rozen
Surgeries 2025, 6(3), 51; https://doi.org/10.3390/surgeries6030051 - 27 Jun 2025
Viewed by 299
Abstract
Preoperative facial markings are critical to surgical precision and aesthetic outcomes in plastic surgery, yet remain operator-dependent and variably documented. Generative artificial intelligence (AI), particularly large multimodal models, offers potential for the automated illustration of surgical plans. This study compares the performances of [...] Read more.
Preoperative facial markings are critical to surgical precision and aesthetic outcomes in plastic surgery, yet remain operator-dependent and variably documented. Generative artificial intelligence (AI), particularly large multimodal models, offers potential for the automated illustration of surgical plans. This study compares the performances of ChatGPT-4o and Gemini Advanced in generating standardised preoperative markings for aesthetic facial procedures. Methods: Six text prompts describing common facial aesthetic surgeries were developed using established marking protocols. Each prompt was submitted once to ChatGPT-4o and Gemini Advanced, yielding twelve illustrations. Three board-certified plastic surgeons independently evaluated the images using a five-domain Likert scale assessing incision clarity, anatomical accuracy, template conformity, clinical usefulness, and overall graphic quality. A composite score out of 25 was calculated. Data were analysed using paired t-tests, and interrater reliability was assessed with intraclass correlation coefficients. Results: ChatGPT-4o significantly outperformed Gemini Advanced in composite scores (mean 18.0 ± 1.4 vs. 13.9 ± 1.6, p = 0.001, Cohen’s d = 1.69). Superior performance was noted across all domains, particularly in clarity (mean difference 0.83, p = 0.002) and graphic quality (mean difference 0.90, p = 0.001). Interrater reliability was good (ICC = 0.82). Discussion: ChatGPT-4o demonstrated higher fidelity in translating surgical prompts into anatomically appropriate, clinically useful illustrations. However, neither system achieved the precision required for clinical implementation without revision. These models may serve as adjuncts in education and preliminary planning. Future work should explore model fine-tuning, surgeon-guided generation, and performance in reconstructive procedures. Full article
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41 pages, 2631 KiB  
Systematic Review
Brain-Computer Interfaces and AI Segmentation in Neurosurgery: A Systematic Review of Integrated Precision Approaches
by Sayantan Ghosh, Padmanabhan Sindhujaa, Dinesh Kumar Kesavan, Balázs Gulyás and Domokos Máthé
Surgeries 2025, 6(3), 50; https://doi.org/10.3390/surgeries6030050 - 26 Jun 2025
Viewed by 557
Abstract
Background: BCI and AI-driven image segmentation are revolutionizing precision neurosurgery by enhancing surgical accuracy, reducing human error, and improving patient outcomes. Methods: This systematic review explores the integration of AI techniques—particularly DL and CNNs—with neuroimaging modalities such as MRI, CT, EEG, and ECoG [...] Read more.
Background: BCI and AI-driven image segmentation are revolutionizing precision neurosurgery by enhancing surgical accuracy, reducing human error, and improving patient outcomes. Methods: This systematic review explores the integration of AI techniques—particularly DL and CNNs—with neuroimaging modalities such as MRI, CT, EEG, and ECoG for automated brain mapping and tissue classification. Eligible clinical and computational studies, primarily published between 2015 and 2025, were identified via PubMed, Scopus, and IEEE Xplore. The review follows PRISMA guidelines and is registered with the OSF (registration number: J59CY). Results: AI-based segmentation methods have demonstrated Dice similarity coefficients exceeding 0.91 in glioma boundary delineation and tumor segmentation tasks. Concurrently, BCI systems leveraging EEG and SSVEP paradigms have achieved information transfer rates surpassing 22.5 bits/min, enabling high-speed neural decoding with sub-second latency. We critically evaluate real-time neural signal processing pipelines and AI-guided surgical robotics, emphasizing clinical performance and architectural constraints. Integrated systems improve targeting precision and postoperative recovery across select neurosurgical applications. Conclusions: This review consolidates recent advancements in BCI and AI-driven medical imaging, identifies barriers to clinical adoption—including signal reliability, latency bottlenecks, and ethical uncertainties—and outlines research pathways essential for realizing closed-loop, intelligent neurosurgical platforms. Full article
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11 pages, 744 KiB  
Article
Short-Term Outcomes of a Novel Fascio-Aponeurotic Flap Technique for Ulnar Nerve Instability at the Elbow
by Rocco De Vitis, Marco D’Orio, Adriano Cannella, Eve Michel Gabriel, Giuseppe Taccardo, Luciana Marzella, Vitale Cilli, Giulia Maria Sassara and Marco Passiatore
Surgeries 2025, 6(3), 49; https://doi.org/10.3390/surgeries6030049 - 24 Jun 2025
Viewed by 175
Abstract
Background: Cubital tunnel syndrome is the second most common compressive neuropathy of the upper limb, and it is characterized by ulnar nerve compression at the elbow. Traditional surgical options, including simple decompression and anterior transposition, have limitations in addressing ulnar nerve instability. This [...] Read more.
Background: Cubital tunnel syndrome is the second most common compressive neuropathy of the upper limb, and it is characterized by ulnar nerve compression at the elbow. Traditional surgical options, including simple decompression and anterior transposition, have limitations in addressing ulnar nerve instability. This study introduces and evaluates the short-term outcomes of a novel surgical technique, the fascio-aponeurotic epicondylar flap (FAEF), for stabilizing the ulnar nerve and managing its instability. Materials and methods: A retrospective study was conducted on ten patients with longstanding cubital tunnel syndrome and confirmed ulnar nerve dislocation or instability. All patients underwent surgical intervention using the FAEF technique, which involves creating a quadrangular fascial flap from the epicondylar fascia to stabilize the ulnar nerve within the retrocondylar groove. Outcomes were assessed using clinical follow-ups, the Michigan Hand Outcomes Questionnaire (MHQ), VAS, and qDASH scores over a 90-day postoperative period. Results: All ten patients experienced complete resolution of neurological symptoms, including paresthesia, pain, and nerve clicking, by the final follow-up. Postoperative recovery was uneventful, with no complications such as infections or hematomas. Grip strength and hand functionality were fully restored, with significant improvements in MHQ scores (mean: 94). Dynamic elbow mobilization initiated on the first postoperative day resulted in full recovery of elbow range of motion. No recurrence of ulnar nerve dislocation was observed. Discussion: The FAEF technique effectively stabilizes the ulnar nerve, alleviates symptoms, and restores function while minimizing risks associated with traditional procedures, such as nerve trauma and elbow instability. By preserving the anatomical integrity of the medial epicondyle and enhancing nerve mobility, this approach represents a less invasive alternative to anterior transposition and medial epicondylectomy. Conclusions: The FAEF technique is a viable and effective surgical option for managing ulnar nerve instability in cubital tunnel syndrome. It offers a less invasive solution with excellent short-term outcomes, making it a promising addition to the surgical armamentarium for this condition. Further studies are warranted to evaluate long-term efficacy and broader applicability. Full article
(This article belongs to the Section Hand Surgery and Research)
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19 pages, 527 KiB  
Systematic Review
Chronic Rhinosinusitis: A Multifaceted Burden on Patients and Society—A Systematic Review
by Doinel G. Rădeanu, Valeriu Bronescu, Constantin Stan, Octavian D. Palade and Alma A. Maniu
Surgeries 2025, 6(3), 48; https://doi.org/10.3390/surgeries6030048 - 23 Jun 2025
Viewed by 259
Abstract
Background/Objectives: Chronic rhinosinusitis (CRS) is a prevalent inflammatory condition of the nasal cavity and paranasal sinuses that significantly impact patients’ quality of life and imposes a substantial burden on healthcare systems and society, including considerable costs associated with surgical management when required. This [...] Read more.
Background/Objectives: Chronic rhinosinusitis (CRS) is a prevalent inflammatory condition of the nasal cavity and paranasal sinuses that significantly impact patients’ quality of life and imposes a substantial burden on healthcare systems and society, including considerable costs associated with surgical management when required. This review aimed to provide a comprehensive overview of the burden of CRS, encompassing its impact on patients, society, and the economy, while also highlighting the latest advancements in diagnosis and treatment. Methods: A systematic review using PubMed, Embase and Google Scholar databases identified recent literature published in English, adhering to PRISMA guidelines. Search terms included “chronic rhinosinusitis”, “burden”, “quality of life”, “economic impact”, “diagnosis”, “treatment”, and “endotypes”. Original research, reviews, and meta-analyses were included, while case reports, surgical-only studies, and non-English articles were excluded. Results: Characterized by persistent symptoms such as nasal congestion, facial pressure, and discharge, CRS often leads to decreased productivity, missed workdays, and impaired sleep. Recent advances in understanding the pathophysiology of CRS have led to the identification of distinct endotypes, including type 2 inflammation characterized by eosinophilic infiltration, and type 1 inflammation with a neutrophilic predominance. Conclusions: This understanding has paved the way for targeted therapies, including biologic agents that have shown promising results in managing CRS, particularly in patients with type 2 inflammation. Full article
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12 pages, 1403 KiB  
Article
Role of Interfragmentary Screw in Metatarsophalangeal Arthrodesis of the Hallux Using a Dorsal Plate: A Retrospective Cohort Study
by Pasquale Ruberto, Guglielmo Miele, Stefano Pace, Alessandro de Silva, Alessandro Smimmo, Andrea De Fazio, Giulio Maccauro, Fabrizio Forconi and Raffaele Vitiello
Surgeries 2025, 6(3), 47; https://doi.org/10.3390/surgeries6030047 - 23 Jun 2025
Viewed by 230
Abstract
Background: Hallux rigidus (HR) is a common forefoot disorder, and surgical treatment is typically guided by the severity of the condition, as defined by the Coughlin and Shurnas four-grade classification. This study aimed to compare clinical and functional outcomes in patients undergoing first [...] Read more.
Background: Hallux rigidus (HR) is a common forefoot disorder, and surgical treatment is typically guided by the severity of the condition, as defined by the Coughlin and Shurnas four-grade classification. This study aimed to compare clinical and functional outcomes in patients undergoing first metatarsophalangeal joint arthrodesis (FMTPJA) with or without the use of an interfragmentary (IF) screw in addition to a dorsal plate. Methods: We retrospectively evaluated a cohort of patients who underwent surgery with a FMTPJA, dividing patients in two groups: patients who underwent FMTPJA through dorsal plate associated with an interfragmentary screw (WIS group) and patients who underwent FMTPJA through dorsal plate without an interfragmentary screw (WOIS group). The primary outcomes were analyzed using the FAAM score and FAAM sport score. Secondary outcomes included VAS, patient satisfaction, recovery time to return to sports, and the level of postoperative sports activity compared to preoperative levels. Results: In paired analyses, the WOIS group showed statistically significant improvements in both the FAAM and FAAM sport scores (p = 0.01). In contrast, the WIS group showed significant improvement only in the FAAM sport score (p = 0.01), while the FAAM score did not reach statistical significance (p = 0.42). Multivariate analysis revealed that a higher preoperative FAAM score predicted a higher postoperative FAAM score (p = 0.75), while the use of an IF screw was associated with a lower expected postoperative FAAM score (p = 0.25). Increased BMI and older age were significantly associated with lower postoperative FAAM scores. Conclusions: Both surgical techniques led to significant clinical improvements. However, patients in the WOIS group showed a trend toward faster recovery and higher postoperative sports activity levels, particularly in the athletic population. Although no statistically significant differences were found between groups overall, these findings suggest potential benefits of avoiding an IF screw in selected patients. Further prospective studies are warranted to better delineate the clinical impact of screw usage in FMTPJA. Full article
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