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Journal of Composites Science, Volume 6, Issue 9

September 2022 - 36 articles

Cover Story: Hemodialysis (HD) is a life-sustaining extracorporeal blood-purifying treatment for end-stage renal disease (ESRD) patients. However, this membrane-based therapy is associated with acute side effects, life-threatening chronic conditions, and unacceptably high morbidity and mortality rates. Heparin is a widely used anticoagulant substance that increases the clotting time and increases the membrane hemocompatibility. However, using heparin is challenging due to its severe or life-threatening side effects, such as heparin-induced thrombocytopenia (HIT), in addition to thrombosis (HITT). Therefore, the current study has thoroughly focused on different heparin HD membrane systems, the challenges of heparin-coated dialysis membranes, and the factors affecting its hemocompatibility, in addition to the methods that can be used to enhance its hemocompatibility. View this paper
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J. Compos. Sci. - ISSN 2504-477X