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Tropical Medicine and Infectious Disease, Volume 7, Issue 2

2022 February - 21 articles

Cover Story: Schistosomiasis is a neglected tropical disease (NTD) endemic in 78 countries. In Madagascar, the condition is widespread and found in 74% of all administrative districts. Like many neglected tropical diseases (NTDs), schistosomiasis is associated with regions of high poverty, low access to healthcare services, and poor sanitation. Geospatial technologies can expand our knowledge of the spatial patterns of schistosomiasis and the potential implications associated with informing national control programs. In addition, because of the focal nature of NTDs such as schistosomiasis, geospatial technologies can inform national surveillance programs while improving understanding of areas in need of medical interventions, especially those underserved populations at the highest risk. View this paper
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Articles (21)

  • Systematic Review
  • Open Access
12 Citations
6,123 Views
12 Pages

The prevalence of visual impairment (VI) continues to rise, despite efforts to reduce it. The burden of disease negatively impacts the quality of life, education opportunities, and other developments in various communities. Henceforth, this study aim...

  • Article
  • Open Access
8 Citations
6,337 Views
15 Pages

Soil-transmitted helminth infections are most prevalent in rural populations. Village health volunteers (VHVs) are the key individuals for Thai primary healthcare. Therefore, this study aimed to investigate the knowledge, attitudes, and practices reg...

  • Review
  • Open Access
21 Citations
5,952 Views
19 Pages

Moonlighting in Rickettsiales: Expanding Virulence Landscape

  • Ana Luísa Matos,
  • Pedro Curto and
  • Isaura Simões

The order Rickettsiales includes species that cause a range of human diseases such as human granulocytic anaplasmosis (Anaplasma phagocytophilum), human monocytic ehrlichiosis (Ehrlichia chaffeensis), scrub typhus (Orientia tsutsugamushi), epidemic t...

  • Article
  • Open Access
9 Citations
3,500 Views
9 Pages

Molecular Survey and Identification of Campylobacter spp. in Layer Farms in Central Ethiopia

  • Behailu Assefa Wayou,
  • Gezahegne Mamo Kassa,
  • Teshale Sori,
  • Alessandra Mondin,
  • Claudia Maria Tucciarone,
  • Mattia Cecchinato and
  • Daniela Pasotto

Few data are available on Campylobacter spp. presence in chickens in Ethiopia. Due to its importance for both the poultry sector and public health, a sampling activity was planned to evaluate Campylobacter spp. presence in layer farms in Bishoftu and...

  • Article
  • Open Access
8 Citations
3,691 Views
11 Pages

Media Exposure, Behavioural Risk Factors and HIV Testing among Women of Reproductive Age in Papua New Guinea: A Cross-Sectional Study

  • Oyelola A. Adegboye,
  • Henry C. Ezechukwu,
  • Hannah Woodall,
  • Megan Brough,
  • Jodie Robertson-Smith,
  • Rosella Paba,
  • Geraint Czech and
  • Theophilus I. Emeto

Background: Reproductive health remains a major health concern in developing countries such as Papua New Guinea (PNG). The prevalence of human immunodeficiency virus (HIV) in PNG is the highest in the Southern Pacific region, with women having a high...

  • Article
  • Open Access
4 Citations
3,075 Views
15 Pages

Antileishmanial Efficacy of the Calpain Inhibitor MDL28170 in Combination with Amphotericin B

  • Marta H. Branquinha,
  • Pedro S. S. Araújo,
  • Simone S. C. Oliveira,
  • Leandro S. Sangenito,
  • Diego S. Gonçalves,
  • Sérgio H. Seabra,
  • Claudia M. d’Avila-Levy and
  • André L. S. Santos

The necessity of drug combinations to treat leishmaniasis came to the surface mainly because of the toxicity of current treatments and the emergence of resistant strains. The calpain inhibitor MDL28170 has previously shown anti-Leishmania activity, t...

  • Article
  • Open Access
9 Citations
3,969 Views
12 Pages

Exposure of South African Abattoir Workers to Coxiella burnetii

  • Liesl De Boni,
  • Sumaya Mall,
  • Veerle Msimang,
  • Alex de Voux,
  • Jennifer Rossouw and
  • John Frean

Abattoir workers may contract Q fever by inhalation of Coxiella burnetii bacteria in aerosols generated by slaughtering livestock, or in contaminated dust. We estimated the seroprevalence of C. burnetii and examined the associated factors in a survey...

  • Article
  • Open Access
28 Citations
4,815 Views
13 Pages

Infectious diseases caused by nontuberculous mycobacteria (NTM) are increasingly common. This retrospective cohort study examined factors associated with outcomes in patients from Shanghai who had NTM pulmonary disease (NTMPD) from January 2014 to De...

  • Article
  • Open Access
8 Citations
4,241 Views
9 Pages

Telehealth Reduces Missed Appointments in Pediatric Patients with Tuberculosis Infection

  • Angela Zhao,
  • Nirali Butala,
  • Casey Morgan Luc,
  • Richard Feinn and
  • Thomas S. Murray

Pediatric patients with untreated tuberculosis infection (TBI), also called latent TBI, are at risk of progression to active TB disease. The primary aim of this study was to identify factors associated with higher rates of missed appointments and fai...

  • Article
  • Open Access
1 Citations
3,451 Views
11 Pages

Francisella is an intracellular, fastidious, Gram-negative bacterium that is difficult to identify using routine microbiological methods in the laboratory. We studied the isolation of Francisella sp. (strain IDAMR664) from the blood of a patient with...

  • Case Report
  • Open Access
5 Citations
4,719 Views
11 Pages

Disseminated Acanthamoeba species infection is likely an underrecognized and underdiagnosed opportunistic infection in patients with advanced human immunodeficiency virus (HIV) disease in South Africa. It presents a unique clinical challenge in that...

  • Brief Report
  • Open Access
8 Citations
4,314 Views
9 Pages

Characterizing Safety and Clinical Outcomes Associated with High-Dose Micafungin Utilization in Patients with Proven Invasive Candidiasis

  • Victoria C. Grant,
  • Kenneth Nguyen,
  • Sasha Rodriguez,
  • Anna Y. Zhou,
  • Jacinda C. Abdul-Mutakabbir and
  • Karen K. Tan

Micafungin is the empiric antifungal agent of choice for the treatment of invasive candidiasis (IC). Pathophysiologic changes that occur in obese and/or critically ill patients can alter micafungin serum concentrations and the probability of target a...

  • Systematic Review
  • Open Access
42 Citations
5,894 Views
19 Pages

Global and Regional Prevalence and Outcomes of COVID-19 in People Living with HIV: A Systematic Review and Meta-Analysis

  • Tope Oyelade,
  • Jaber S. Alqahtani,
  • Ahmed M. Hjazi,
  • Amy Li,
  • Ami Kamila and
  • Reynie Purnama Raya

Background: The relationship between HIV (human immunodeficiency virus) and COVID-19 clinical outcome is uncertain, with conflicting data and hypotheses. We aimed to assess the prevalence of people living with HIV (PLWH) among COVID-19 cases and whet...

  • Article
  • Open Access
7 Citations
4,102 Views
12 Pages

Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa

  • Anja Reuter,
  • Buci Beko,
  • Boniwe Memani,
  • Jennifer Furin,
  • Johnny Daniels,
  • Erickmar Rodriguez,
  • Hermann Reuter,
  • Lize Weich,
  • Petros Isaakidis and
  • Erika Mohr-Holland
  • + 2 authors

Substance use (SU) is associated with poor rifampicin-resistant tuberculosis (RR-TB) treatment outcomes. In 2017, a SBIRT (SU screening-brief intervention-referral to treatment) was integrated into routine RR-TB care in Khayelitsha, South Africa. Thi...

  • Article
  • Open Access
10 Citations
4,689 Views
12 Pages

The Usefulness of Peripheral Blood Cell Counts to Distinguish COVID-19 from Dengue during Acute Infection

  • Juan Fidel Osuna-Ramos,
  • José Manuel Reyes-Ruiz,
  • Luis Antonio Ochoa-Ramírez,
  • Luis Adrián De Jesús-González,
  • Rosalío Ramos-Payán,
  • Carlos Noe Farfan-Morales,
  • Alejandra Romero-Utrilla,
  • Efrén Rafael Ríos-Burgueño,
  • José Rodríguez-Millán and
  • Jesús Salvador Velarde-Félix
  • + 1 author

COVID-19 and dengue disease are challenging to tell apart because they have similarities in clinical and laboratory features during the acute phase of infection, leading to misdiagnosis and delayed treatment. The present study evaluated peripheral bl...

  • Article
  • Open Access
3 Citations
3,834 Views
11 Pages

Evaluating the Quality of Latent Tuberculosis Infection Screening in Ireland: A Single-Centre Retrospective Cohort Study

  • James O’Connell,
  • Joy Oguntuase,
  • Brian Li,
  • Cora McNally,
  • Debbi Stanistreet,
  • Samuel McConkey and
  • Eoghan de Barra

Ireland is a country with a low incidence of tuberculosis (TB) (5.6 cases per 100,000 population in 2019) that should be aiming for TB elimination (fewer than 1 case per million of population). To achieve TB elimination in low-incidence countries, pr...

  • Review
  • Open Access
7 Citations
7,735 Views
11 Pages

Rickettsiosis in Southeast Asia: Summary for International Travellers during the COVID-19 Pandemic

  • Thundon Ngamprasertchai,
  • Borimas Hanboonkunupakarn and
  • Watcharapong Piyaphanee

Rickettsiosis is an important cause of febrile illness among travellers visiting Southeast Asia (SEA). The true incidence of rickettsiosis is underestimated; however, murine typhus and scrub typhus are widely distributed across SEA. Among travellers...

  • Article
  • Open Access
23 Citations
8,292 Views
17 Pages

Schistosomiasis is a neglected tropical disease (NTD) found throughout tropical and subtropical Africa. In Madagascar, the condition is widespread and endemic in 74% of all administrative districts in the country. Despite the significant burden of th...

  • Communication
  • Open Access
4 Citations
4,142 Views
6 Pages

Hepatitis C virus (HCV) is a significant public health problem, and the elimination of its infection by 2031 is a global goal. However, due to insufficient testing, lack of linkage to care (LTC) and treatment, Libya may be far from achieving this goa...

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Trop. Med. Infect. Dis. - ISSN 2414-6366