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Tomography, Volume 7, Issue 3

September 2021 - 19 articles

Cover Story: This paper investigates the error that results when quantitatively analyzing abbreviated dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data of the breast with the Standard Kety–Tofts model and its Patlak variant. We performed simulations and analyzed patient data to determine the accuracy with which abbreviated time-courses could reproduce the pharmacokinetic parameters, Ktrans (volume transfer constant) and ve (extravascular extracellular volume fraction) when compared to the full time-courses. Most of the analyzed patients had high Ktrans agreement for an abbreviation as short as 4.5 minutes. The results indicate the potential of performing a quantitative analysis of abbreviated breast DCE-MRI without significant loss of information; furthermore, this can be accomplished in the community-based care setting. View this paper
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Articles (19)

  • Article
  • Open Access
13 Citations
3,909 Views
11 Pages
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Radiomics for Everyone: A New Tool Simplifies Creating Parametric Maps for the Visualization and Quantification of Radiomics Features

  • Damon Kim,
  • Laura J. Jensen,
  • Thomas Elgeti,
  • Ingo G. Steffen,
  • Bernd Hamm and
  • Sebastian N. Nagel
Tomography2021, 7(3), 477-487;https://doi.org/10.3390/tomography7030041

17 September 2021

Aim was to develop a user-friendly method for creating parametric maps that would provide a comprehensible visualization and allow immediate quantification of radiomics features. For this, a self-explanatory graphical user interface was designed, and...

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  • Article
  • Open Access
20 Citations
3,987 Views
15 Pages
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Evaluation of Regional Lung Function in Pulmonary Fibrosis with Xenon-129 MRI

  • Jaime Mata,
  • Steven Guan,
  • Kun Qing,
  • Nicholas Tustison,
  • Yun Shim,
  • John P. Mugler,
  • Talissa Altes,
  • Jhosep Huaromo and
  • Borna Mehrad
Tomography2021, 7(3), 452-465;https://doi.org/10.3390/tomography7030039

15 September 2021

Idiopathic pulmonary fibrosis, a pattern of interstitial lung disease, is often clinically unpredictable in its progression. This paper presents hyperpolarized Xenon-129 chemical shift imaging as a noninvasive, nonradioactive method of probing lung p...

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  • Article
  • Open Access
3 Citations
2,835 Views
12 Pages
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Metabolite-Specific Echo-Planar Imaging of Hyperpolarized [1-13C]Pyruvate at 4.7 T

  • Tyler Blazey,
  • Galen D Reed,
  • Joel R Garbow and
  • Cornelius von Morze
Tomography2021, 7(3), 466-476;https://doi.org/10.3390/tomography7030040

15 September 2021

Although hyperpolarization (HP) greatly increases the sensitivity of 13C MR, the usefulness of HP in vivo is limited by the short lifetime of HP agents. To address this limitation, we developed an echo-planar (EPI) sequence with spectral-spatial radi...

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  • Article
  • Open Access
1 Citations
3,343 Views
19 Pages
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Radiofrequency Bias Correction of Magnetization Prepared Rapid Gradient Echo MRI at 7.0 Tesla Using an External Reference in a Sequential Protocol

  • Hampus Olsson,
  • Mikael Novén,
  • Jimmy Lätt,
  • Ronnie Wirestam and
  • Gunther Helms
Tomography2021, 7(3), 434-451;https://doi.org/10.3390/tomography7030038

13 September 2021

At field strengths of 7 T and above, T1-weighted imaging of human brain suffers increasingly from radiofrequency (RF) B1 inhomogeneities. The well-known MP2RAGE (magnetization prepared two rapid acquisition gradient echoes) sequence provides a soluti...

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  • Essay
  • Open Access
18 Citations
6,420 Views
10 Pages
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Identification of Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT)

  • Giovanni Foti,
  • Gerardo Serra,
  • Venanzio Iacono and
  • Claudio Zorzi
Tomography2021, 7(3), 424-433;https://doi.org/10.3390/tomography7030037

3 September 2021

Dual-energy computed tomography (DECT) has been reported to successfully identify bone marrow oedema (BME) in various traumatic settings. DECT has multiple strengths, including the availability of both a 3D view of the anatomical area studied and of...

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  • Article
  • Open Access
4 Citations
2,573 Views
12 Pages
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Branch Pulmonary Artery Regurgitation in Repaired Tetralogy of Fallot: Correlation with Pulmonary Artery Morphology, Distensibility, and Right Ventricular Function

  • Suvipaporn Siripornpitak,
  • Duangkanok Lueangwattanapong,
  • Apichaya Sriprachyakul,
  • Suthep Wanitkun and
  • Alisa Limsuwan
Tomography2021, 7(3), 412-423;https://doi.org/10.3390/tomography7030036

1 September 2021

Background: The aim was to determine the effect of pulmonary artery (PA) morphology on the branch pulmonary artery-regurgitation fraction (BPA-RF), the relationship of pulmonary insufficiency (PI) to BPA-RF and PA-distensibility, and factors (BPA-RF...

Full Article
  • Review
  • Open Access
12 Citations
6,828 Views
15 Pages
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Idiopathic Interstitial Pneumonias and COVID-19 Pneumonia: Review of the Main Radiological Features and Differential Diagnosis

  • Alessia Guarnera,
  • Elena Santini and
  • Pierfrancesco Podda
Tomography2021, 7(3), 397-411;https://doi.org/10.3390/tomography7030035

31 August 2021

COVID-19 pneumonia represents a challenging health emergency, due to the disproportion between the high transmissibility, morbidity, and mortality of the virus and healthcare systems possibilities. Literature has mainly focused on COVID-19 pneumonia...

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  • Essay
  • Open Access
22 Citations
5,214 Views
10 Pages
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Identification of Non-Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT)

  • Giovanni Foti,
  • Gerardo Serra,
  • Venanzio Iacono,
  • Stefania Marocco,
  • Giulia Bertoli,
  • Stefania Gori and
  • Claudio Zorzi
Tomography2021, 7(3), 387-396;https://doi.org/10.3390/tomography7030034

26 August 2021

Dual-energy computed tomography (DECT) is an imaging technique widely used in traumatic settings to diagnose bone marrow oedema (BME). This paper describes the role of DECT in diagnosing BME in non-traumatic settings by evaluating its reliability in...

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  • Article
  • Open Access
7 Citations
4,802 Views
14 Pages
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Retrospective Cohort Study of Frequency and Patterns of Orbital Injuries on Whole-Body CT with Maxillofacial Multi-Slice CT

  • Leonie Goelz,
  • Annika Syperek,
  • Stephanie Heske,
  • Sven Mutze,
  • Norbert Hosten and
  • Michael Kirsch
Tomography2021, 7(3), 373-386;https://doi.org/10.3390/tomography7030033

17 August 2021

Background: High-impact trauma frequently leads to injuries of the orbit, but literature focusing on the viscerocranium rather than the neurocranium is underrepresented. Methods: Retrospective cohort study (2006–2014) at an urban level 1 trauma cente...

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  • Article
  • Open Access
12 Citations
6,230 Views
15 Pages
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Detection of Lung Nodules in Micro-CT Imaging Using Deep Learning

  • Matthew D. Holbrook,
  • Darin P. Clark,
  • Rutulkumar Patel,
  • Yi Qi,
  • Alex M. Bassil,
  • Yvonne M. Mowery and
  • Cristian T. Badea
Tomography2021, 7(3), 358-372;https://doi.org/10.3390/tomography7030032

7 August 2021

We are developing imaging methods for a co-clinical trial investigating synergy between immunotherapy and radiotherapy. We perform longitudinal micro-computed tomography (micro-CT) of mice to detect lung metastasis after treatment. This work explores...

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Tomography - ISSN 2379-139X
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