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Tomography, Volume 11, Issue 12

2025 December - 13 articles

Cover Story: Chest CT scans are important for monitoring lung problems in people with cystic fibrosis (CF). However, repeated scans can expose patients to radiation, which is a concern as people with CF are now living longer due to improved treatment options. A newer type of CT technology, called photon-counting CT (PCCT), may help reduce this radiation. In this study, researchers compared two PCCT settings (low-dose and ultra-low-dose) in 72 people with CF. The results showed that the ultra-low-dose PCCT scans used about 65% less radiation than the low-dose version. Even though the image quality was slightly lower, doctors still rated the ultra-low-dose version as good enough for diagnosis. In fact, the radiation from the ultra-low-dose scan was only about twice that of a standard two-view chest X-ray, which is very low for a CT scan. View this paper
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Articles (13)

  • Review
  • Open Access
1 Citations
1,964 Views
27 Pages

Cancer-Associated Fibroblasts: Clinical Applications in Imaging and Therapy

  • Neda Nilforoushan,
  • Ashkan Khavaran,
  • Maierdan Palihati,
  • Yashvi Patel,
  • Anna O. Giarratana,
  • Jeeban Paul Das and
  • Kathleen M. Capaccione

17 December 2025

Cancer-associated fibroblasts (CAFs) are an abundant and diverse cell population within tumor microenvironments of solid tumors. Multiple subtypes of CAFs, defined by molecular and functional markers, have been described in the literature. CAFs contr...

  • Article
  • Open Access
486 Views
16 Pages

Prediction of Breast Radiation Absorbed Dose Chest CT Examinations Using Machine Learning Techniques

  • Sevgi Ünal,
  • Remzi Gürfidan,
  • Merve Gürsoy Bulut and
  • Mustafa Fazıl Gelal

16 December 2025

Background/Objectives: The breast is a highly radiosensitive organ that is directly exposed to ionizing radiation during chest computed tomography (CT) examinations. Excessive radiation exposure increases the risk of radiation-induced malignancies, h...

  • Article
  • Open Access
524 Views
11 Pages

16 December 2025

Background: Accurate volumetry and imaging characterization of chronic subdural hematoma (cSDH) are essential for prognostication and treatment planning, but manual assessment is time-consuming and therefore underutilized. Methods: We retrospectively...

  • Article
  • Open Access
518 Views
12 Pages

Pilot Evaluation of a Deep Learning Model for Nasogastric Tube Verification on Chest Radiographs: A Single-Center Retrospective Study

  • Sang Won Park,
  • Doohee Lee,
  • Jae Eun Song,
  • Yoon Kim,
  • Hyun-Soo Choi,
  • Seung-Joon Lee,
  • Woo Jin Kim,
  • Kyoung Min Moon and
  • Oh Beom Kwon

15 December 2025

Background: Accurate confirmation of nasogastric (NG) tubes is essential for patient safety, but delays and variability in interpretation remain common in clinical practice. Deep learning (DL) models have shown potential for assisting in this task, b...

  • Article
  • Open Access
777 Views
12 Pages

Aortic Valve Calcium Scoring Using True and Virtual Non-Contrast Reconstructions on Photon-Counting CT with Differing Slice Increments: Impact on Calcium Severity Classifications

  • Mandeep Singh,
  • Amirhossein Moaddab,
  • Doosup Shin,
  • Jonathan Weber,
  • Karen Chau,
  • Ali H. Dakroub,
  • Roosha Parikh,
  • Karli Pipitone,
  • Ziad A. Ali and
  • Omar K. Khalique

11 December 2025

Background/Objectives: Aortic valve calcification is commonly evaluated using 3.0 mm true non-contrast (TNC) computed tomography (CT) images. This study evaluates the reproducibility of virtual non-contrast (VNC) reconstructions at different slice in...

  • Article
  • Open Access
560 Views
15 Pages

10 December 2025

Background/Objectives: Breast cancer is one of the most common malignancies in women worldwide. Early diagnosis and accurate classification in breast cancer detection are among the most critical factors determining treatment success and patient survi...

  • Article
  • Open Access
456 Views
16 Pages

5 December 2025

Background/Objectives: To identify preoperative MRI features using computer-assisted diagnosis (CAD) that are associated with invasive disease-free survival (IDFS) and distant metastasis-free survival (DDFS) in patients with primarily operable triple...

  • Article
  • Open Access
526 Views
14 Pages

Quantitative Magnetic Resonance Imaging of the Forearm in Myotonic Dystrophy Type 1

  • Sydney Eierle,
  • Tanja Taivassalo,
  • Hyunjun Park,
  • Korey D. Cooke,
  • Zahra Moslemi,
  • Sean C. Forbes,
  • Glenn A. Walter,
  • Krista Vandenborne,
  • S. H. Subramony and
  • Donovan J. Lott

5 December 2025

Introduction: Myotonic dystrophy type 1 is the most prevalent muscular dystrophy in adults, characterized by weakness, impaired functional abilities, and myotonia. However, little is known about the relationship between quantitative MRI measures (fat...

  • Article
  • Open Access
636 Views
15 Pages

Evaluation of Projection Images for Visual Quality Control of Automated Left and Right Lung Segmentations on T1-Weighted MRI in Large-Scale Clinical Cohort Studies

  • Tobias Norajitra,
  • Christopher L. Schlett,
  • Ricarda von Krüchten,
  • Prerana Agarwal,
  • Ashis Ravindran,
  • Thuy Duong Do,
  • Lisa Kausch,
  • Stefan Karrasch,
  • Hans-Ulrich Kauczor and
  • Claudius Melzig
  • + 1 author

29 November 2025

Background/Objectives: To assess diagnostic accuracy of two-dimensional (2D) projection methods for rapid visual quality control of automated volumetric (3D) lung segmentations compared with slice-based 3D review of segmentation results for applicati...

  • Article
  • Open Access
999 Views
11 Pages

A Question of Dose? Ultra-Low Dose Chest CT on Photon-Counting CT in People with Cystic Fibrosis

  • Marcel Opitz,
  • Matthias Welsner,
  • Halil I. Tazeoglu,
  • Florian Stehling,
  • Sivagurunathan Sutharsan,
  • Dirk Westhölter,
  • Erik Büscher,
  • Christian Taube,
  • Nika Guberina and
  • Marko Frings
  • + 7 authors

27 November 2025

Objective: Chest computed tomography (CT) is a key component of the diagnostic assessment of people with cystic fibrosis (PwCF) and is increasingly replacing chest radiography. Due to improvements in life expectancy, radiation exposure has become a g...

  • Article
  • Open Access
1,303 Views
14 Pages

Quantitative Ultrasound Grayscale Analysis and Size of Benign and Malignant Solid Thyroid Nodules

  • Salahaden R. Sultan,
  • Faisal Albin Hajji,
  • Abdulrahman Alhazmi,
  • Shahad Alamri,
  • Abrar Alsulami,
  • Ahmed Albukhari,
  • Asseel Filimban,
  • Bander Almutairi,
  • Ahmad Albngali and
  • Abrar Alfatni
  • + 4 authors

27 November 2025

Background: Ultrasound is the primary imaging modality for evaluating thyroid nodules, with echogenicity and nodule size serving as parameters for malignancy risk stratification. Though the TI-RADS classification system is standardized, interpretatio...

  • Article
  • Open Access
965 Views
15 Pages

Accuracy of Ultra-Fast Low-Field MRI (0.55 T) for Lung Nodule Detection with Ultra-Short Echo Time Sequences

  • Maximilian Hinsen,
  • Armin Michael Nagel,
  • Nadine Bayerl,
  • Hans-Peter Fautz,
  • Thomas Benkert,
  • Matthias Stefan May,
  • Michael Uder and
  • Rafael Heiss

26 November 2025

Lung nodules are a common radiological finding that can be caused by a variety of reasons, ranging from benign granulomas and scarring to the early stages of primary lung malignancies and metastases [...]

  • Article
  • Open Access
617 Views
17 Pages

3D Imaging of Proton FLASH Radiation Using a Multi-Detector Small Animal PET System

  • Wen Li,
  • Yuncheng Zhong,
  • Youfang Lai,
  • Lingshu Yin,
  • Daniel Sforza,
  • Devin Miles,
  • Heng Li and
  • Xun Jia

26 November 2025

Objectives: Ultra-high dose-rate FLASH radiotherapy has demonstrated strong potential in reducing normal tissue toxicity while maintaining effective tumor control. However, its underlying radiobiological mechanisms remain unclear, highlighting the ne...

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Tomography - ISSN 2379-139X