Toxics, Volume 13, Issue 5

The concurrent use of (a) diuretics, (b) renin–angiotensin–aldosterone system inhibitors (RAASIs), and (c) non-steroidal anti-inflammatory drugs (NSAIDs) or metamizole, known as the triple whammy (TW) combination, increases the risk of ac...

Background/Objectives: The leakage of 5-fluorouracil (5-FU) from elastomeric infusion pumps used in cancer therapy poses a potential risk of unintentional exposure to multiple individuals, including patients’ relatives and healthcare profession...

Lead (Pb) is recognized as an environmental pollutant with male reproductive toxicity, but its effects on sex hormones remain unclear. This study investigated the relationship between male blood lead levels (BLLs) and the sex hormones of luteinizing...

Evidence highlights the association between endocrine-disrupting chemicals (EDCs) found in personal care and household products (PCHPs) and adverse reproductive and developmental health outcomes. Women are disproportionately at risk due to frequent u...

Sublancin, an S-linked antimicrobial (glycol) peptide produced by Bacillus subtilis, has emerged as a novel and promising veterinary drug due to its unique antibacterial mechanism, low risk of resistance, and properties that modulate the immune syste...

Background: Previous studies have demonstrated that involuntary smoking (e.g., secondhand smoke [SHS] and thirdhand smoke [THS]) is not only associated with an increased risk of several physical health problems, such as cardiovascular disease and can...

In pathology laboratories, several volatile organic compounds (VOCs) are used, such as formaldehyde, ethanol, and xylene. These substances are recognized as genotoxic and cytotoxic, which is why their handling poses risks to human health. The buccal...

The subcellular partitioning of trace elements (TEs) may depend on their binding preferences, although few field data are available from mining-impacted areas. Northern pike and lake whitefish were collected from different aquatic systems located in...

Coffee and coffee by-products, such as coffee cherries, coffee flowers, coffee leaves, green beans, roasted coffee, instant coffee, spent coffee grounds, and silverskin, contain a complex mixture of bioactive compounds that may exhibit both genotoxic...

Heavy metal and pesticide contaminations represent significant environmental and health hazards to humans and animals. Toxic heavy metals such as lead (Pb), cadmium (Cd), mercury (Hg), and copper (Cu) persist in the environment, bioaccumulating in be...

Metformin is the preferred first-line treatment for non-insulin-dependent diabetes mellitus, known for its benefits in cancer suppression, weight loss, and antiketogenic activity. It is a leading drug regarding mass distribution, and its high solubil...

The phytotoxicity of aluminum (Al) to plants is well known. Auxin accumulation and reactive oxygen species (ROS) burst induced by Al toxicity are the key factors in root growth inhibition. Yucasin, an auxin synthesis inhibitor, effectively ameliorate...

Biological degradation effectively removes benzo(a)pyrene (BaP) from contaminated soil; however, knowledge regarding the contributions of plant absorption, microbial degradation, and volatilization to BaP removal remains limited. In this study, the B...

Dietary exposure to a high dose of cadmium (Cd) ≥ 100 µg/day for at least 50 years or a lifetime intake of Cd ≥ 1 g can cause severe damage to the kidneys and bones. Alarmingly, however, exposure to a dose of Cd between 10 and 15 µg...

Polycyclic aromatic hydrocarbons (PAHs) and their substituted derivatives (SPAHs) are persistent organic pollutants derived from incomplete combustion of fossil fuels and industrial processes. These compounds are of global concern due to their carcin...

Pulmonary exposure to carbon nanotubes (CNTs) has been linked to a series of adverse respiratory effects in animal models, including inflammation, genotoxicity, fibrosis, and granuloma formation, the degree and characteristics of which are considered...

Toxicity and pollution of heavy metals in water environments are very serious threats, and how to efficiently remove heavy metals is a difficult problem in water ecosystems. This study takes Cr and Pb as examples to study the adsorption effects of di...

This study focused on microplastic pollution in the Bohai Sea, employing bibliometric analysis and meta-integration methods to systematically analyze its pollution characteristics and ecological risks. The results indicated that microplastics primari...

A considerable number of organizations are working to improve food safety, with particular attention to vulnerable groups such as pregnant women due to the important influence of diet on fetal development. The aim of this study was to evaluate exposu...

This study investigates the physicochemical and toxicological properties of Scalmalloy powder emissions generated during Laser Powder Bed Fusion (LPBF), focusing on the impact of particle morphology, oxidation, and size distribution on biological res...

With industrial development, endocrine-disrupting chemicals have continued to accumulate in the environment, attracting growing attention due to their potential effects on biological health. The reproductive toxicity of diethylstilbestrol (DES), a sy...

Exhaust emissions from ships are significant threats to the environment and human health, necessitating effective control measures and treatment technologies. In response to the increasing stringency of emission regulations set by the International M...

The agricultural production process contributes to the global issue of pesticide pollution. Based on the static toxicity test of diuron (DCMU) on Daphnia magna (D. magna) for EC₅₀-48 h, a concentration range of 0.2 to 1 mg/L was set as sublethal conc...

Water hardening and NO₃⁻ pollution have affected water quality globally. These environmental problems threaten social sustainability and human health, especially in piedmont agricultural areas. The aim of this study is to determine the biogeoch...

Nitrate (NO₃⁻) pollution resulting from anthropogenic activities represents one of the most prevalent environmental issues in karst spring catchments of northern China. In June 2021, a comprehensive study was conducted in the Jinan Spring Catch...

Accurate estimation of ambient PM_2.5 concentrations is crucial for assessing air quality and health risks, particularly in regions with limited ground-based monitoring. Satellite-retrieved data products, such as top-of-atmosphere reflectance (TOAR) a...

Polychlorinated biphenyls (PCBs) are classified as persistent organic pollutants (POPs) due to their potential threat to both ecosystems and human health. The Tibetan Plateau (TP), characterized by its low temperatures, pristine ecological conditions...

The rhizosphere is a crucial interface that connects the soil and the roots of plants, playing a critical role in regulating soil biochemical functions and processes. Biochar, an increasingly common soil amendment, can directly or indirectly affect t...

Staphylococcus aureus is associated with human infections, being a resistant bacterium involved in serious infections, and its virulence and resistance are linked to oxidative stress. In this study, we review the role of oxidative stress in the patho...

The usage of plastics in life and industrial applications has led to global environmental pollution by micro- and nanoplastics (MPs/NPs). Despite their widespread occurrence in the environment, little is known about their presence in humans and the p...

Airborne micro and nanoplastics (MPs/NPs) are a growing issue due to their possible health hazards. Since the current bibliography lacks a thorough evaluation, this review examines the sources, environmental dynamics, and health impacts of airborne M...

Antimicrobial fragrances, commonly found in household and personal care products, are frequently detected in water bodies, yet their environmental fate and transformation mechanisms remain inadequately explored. This study investigates the photochemi...

With the acceleration of urbanization, the diffusion mechanism of urban non-point source (NPS) pollution caused by extreme rainfall is not clear, which leads to high cost and difficulty in water environment treatment. In view of the shortcomings of d...

Benzo[a]pyrene (B[a]P) is a widespread and persistent organic pollutant that poses serious threats to human health. Although its carcinogenic properties have been extensively studied, its developmental toxicity and underlying mechanisms remain poorly...

Quantitative structure–activity relationship (QSAR) models are essential for predicting endpoints that are otherwise challenging to estimate using other in silico approaches. Developing interpretable models for endpoint prediction is valuable a...

Nitrofurantoin, a commonly prescribed antibiotic for urinary tract infections, has been associated with rare but potentially serious pulmonary toxicity, which can present in acute, subacute, or chronic forms. Acute toxicity typically manifests in the...

Heavy metals (HMs) persist in the environment and enter the human body via various pathways. Once stored in adipose tissue, they can be transferred to breast milk, posing risks to infants. Moreover, maternal diet plays a key role in influencing HM le...

Studies analyzing the prevalence of associated substance use are limited. Currently, the World Health Organization (WHO) defines polydrug use as the concurrent (simultaneous use) or sequential (use of one drug followed by another) abuse of more than...

Dimethyl phthalate (DMP) can enter the human body and be absorbed into the bloodstream to produce monomethyl phthalate (MMP). MMP in the environment can also enter the bloodstream. However, little is known about the toxicity of the phthalate metaboli...

The combined pollution of cadmium (Cd) and enrofloxacin (ENR) in aquatic environments represents a critical issue in environmental toxicology. Using zebrafish as model organisms, we systematically investigated the combined toxicity of Cd and ENR thro...

Heavy metal exposure is a significant public health problem, especially among children, who are a particularly vulnerable group. This study investigates the non-dietary exposure of children to lead, cadmium, and zinc and the associated health risk in...

The increasing pollution of polystyrene (PS) and polymethyl methacrylate (PMMA) microplastics (MPs) has become a global marine environmental problem. Diatoms contribute nearly 40% of marine primary productivity and shape the nitrogen cycle in the oce...

Pesticide exposure poses a significant health risk, with emerging evidence suggesting its impact on auditory function. This study investigated the effects of pesticide exposure on hearing in young rural residents living near agricultural areas in Chi...

Mussels are highly efficient filter feeders, playing a crucial role in managing eutrophication and assessing pollution. Although research on nanoplastic (NP) toxicity in marine organisms is expanding, studies on freshwater species remain limited desp...

Purpose: Glyphosate and glyphosate-based herbicides (GBHs) are widely used across the globe. Experimental research indicates that these herbicides may elevate oxidative stress and impair mitochondrial function. However, the relationship between glyph...

The COVID-19 pandemic has exacerbated the problem of environmental contamination of disposable personal protective equipment, in particular face masks (FMs). As a result of environmental factors, FMs undergo aging and fragmentation processes and beco...

The protective potentials of Tribulus terrestris (TT) and L-arginine (L-Arg) against reproductive toxicity induced by fipronil (FPN) in male rats were investigated. A total of 36 male rats were allocated into six groups: control, TT, L-Arg, FPN, FPN...

The rapid increase in construction and demolition waste (C&DW) has emerged as a significant environmental challenge, particularly due to the hazardous substances embodied within the fine residues destined into landfills. The disposal of C&DW...

Environmental pollution significantly exacerbates various diseases, particularly those affecting the cardiovascular and respiratory systems. Our previous studies have shown that acrolein, an environmental pollutant, promotes atherosclerosis by downre...

The experiments in this study investigated the toxicity of naphthenic acids (NAs) on the algal culture Spirulina platensis. The tests monitored the progression of the algal suspension in media contaminated with various concentrations of naphthenic ac...