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Chemosensors, Volume 13, Issue 6

June 2025 - 28 articles

Cover Story: Early-stage detection of gastric cancer is crucial, as late diagnosis remains a major cause of mortality. Tumor biomarkers such as CA12-5, CA72-4, HER1, and AFP offer valuable insights for diagnosis and treatment monitoring. This study presents three novel 3D stochastic sensors using graphite, graphene, and nanographene modified with an oleamide for the simultaneous detection and quantification of these four biomarkers in whole blood, saliva, urine, and gastric tumor tissue. The graphene-based sensor showed the best performance, with high sensitivity, wide linear ranges, and an RSD below 1%, offering a promising tool for fast, multiplexed, and point-of-care cancer screening. View this paper
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Articles (28)

  • Review
  • Open Access
1 Citations
1,983 Views
33 Pages

Advanced Biosensing Technologies: Leading Innovations in Alzheimer’s Disease Diagnosis

  • Stephen Rathinaraj Benjamin,
  • Fábio de Lima,
  • Paulo Iury Gomes Nunes,
  • Rosa Fireman Dutra,
  • Geanne Matos de Andrade and
  • Reinaldo B. Oriá

Diagnosing Alzheimer’s disease (AD) remains a significant challenge due to its multifactorial nature and the limitations of traditional diagnostic methods, such as clinical assessments and neuroimaging, which often lack the specificity and sens...

  • Article
  • Open Access
1,043 Views
19 Pages

Chemical nanosensors based on tin dioxide (SnO2) and zinc oxide (ZnO) nanoparticles (NPs) were developed and characterized for the detection of low concentrations of atmospheric pollutants, such as nitrogen dioxide (NO2) and carbon monoxide (CO). The...

  • Article
  • Open Access
2 Citations
3,548 Views
18 Pages

Trimethylamine Gas Sensor Based on Electrospun In2O3 Nanowires with Different Grain Sizes for Fish Freshness Monitoring

  • Xiangrui Dong,
  • Bo Zhang,
  • Mengyao Shen,
  • Qi Lu,
  • Hao Shen,
  • Yi Ni,
  • Yuechen Liu and
  • Haitao Song

Seafood, especially marine fish, is highly prone to spoilage during processing, transportation, and storage. It releases pungent trimethylamine (TMA) gas, which severely affects food quality and safety. Metal–oxide–semiconductor (MOS) gas...

  • Review
  • Open Access
2 Citations
2,612 Views
37 Pages

Field-effect transistor (FET) chemical sensors are essential for enabling sophisticated lifestyles and ensuring safe working environments. They can detect a wide range of analytes, including gaseous species (NO2, NH3, VOCs), ionic compounds, and biol...

  • Article
  • Open Access
1 Citations
1,465 Views
11 Pages

Ultraflexible Chemiresistive NO2 Gas Sensor Realized with Photopatterned Porous Polymer Film

  • Xingda Yi,
  • Banghua Wu,
  • Lin Gao,
  • Yujie Peng,
  • Yong Huang and
  • Junsheng Yu

The development of ultraflexible and sensitive gas sensors is critical for advancing next-generation environmental monitoring and healthcare diagnostics. In this work, we demonstrate an ultraflexible chemiresistive nitrogen dioxide (NO2) sensor integ...

  • Perspective
  • Open Access
1 Citations
2,979 Views
29 Pages

Although traditional drug delivery methods are widely used in clinical practice, their inherent limitations often compromise therapeutic efficacy. Therefore, the development of more precise and efficient drug delivery systems is essential to enhance...

  • Article
  • Open Access
957 Views
16 Pages

The electrochemical polymerization of guaiacol was studied in different organic solvents. Significant electrode blocking was observed in dichloromethane. Microscopic studies verified the formation of a coherent deposit on the platinum electrode. In a...

  • Communication
  • Open Access
1 Citations
1,503 Views
11 Pages

Analysis of Ergothioneine Using Surface-Enhanced Raman Scattering: Detection in Mushrooms

  • Federico Puliga,
  • Veronica Zuffi,
  • Alessandra Zambonelli,
  • Pavol Miškovský,
  • Ornella Francioso and
  • Santiago Sanchez-Cortes

Surface-enhanced Raman scattering (SERS) spectroscopy is a straightforward analytical technique capable of providing detailed information about metabolites in biological samples. The objective of this study was to perform a SERS analysis of ergothion...

  • Article
  • Open Access
1,223 Views
14 Pages

Green On-Site Diclofenac Extraction from Wastewater Matrices Using a 3D-Printed Device Followed by PTV-GC-MS Determination

  • César Castro-García,
  • Edwin Palacio,
  • Rogelio Rodríguez-Maese,
  • Luz O. Leal and
  • Laura Ferrer

A 3D-printed device was designed and printed by a stereolithographic technique (SLA) and coated with a highly selective solid phase extraction resin for on-site diclofenac extraction from wastewater, avoiding the transport and treatment of large volu...

  • Communication
  • Open Access
3,131 Views
10 Pages

This study presents a microbial sensing device that employs a poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) matrix to immobilize viable and metabolically Escherichia coli cells. This device enables the monitoring of microorganism...

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Chemosensors - ISSN 2227-9040Creative Common CC BY license