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Biomolecules, Volume 14, Issue 11
November 2024 - 139 articles
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Cover Story: Unmistakable accounts of cancer with clinical characteristics, as are understood today, begin in the fifth century B.C. with Hippocrates of Cos and later in the second century A.D. with Galen of Pergamum, addressing the incidence of cancer, predominantly in advanced age, the clinical characteristics of the disease, its life‑threatening course, and attempts to treat it. The principles and practices of the Hippocratic and Galenic traditions—especially the concept of early cancer detection to ensure cure—have virtually dominated cancer care well into the 20th century. Sequencing technologies at the dawn of the 21st century have opened a new era of therapeutic intervention, broadly, as well as at the level of personal genomes. Gene therapy for cancer treatment encompasses different approaches such as immunotherapy, oncolysis mediated by viruses, and gene transfer. View this paper
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