Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives

Dear Colleagues,

Obesity is a significant public health concern due to its close link with metabolic comorbidities, such as type 2 diabetes, dyslipidemia, liver diseases, and cardiovascular diseases. Evidence suggests that excessive or inappropriate nutrient intake triggers chronic inflammatory responses in tissues that regulate metabolic homeostasis, leading to altered metabolic pathways, insulin resistance, and systemic metabolic dysfunction. Nutritional interventions have emerged as effective strategies for managing obesity and associated metabolic disorders.

In this Special Issue, we aim to cover the molecular significance of both macro- and micro-nutrients, as well as the current dietary recommendations. We will explore the primary metabolic pathways and molecular mechanisms in which each nutrient plays a role, and their contribution to the development of obesity and/or metabolic diseases. Importantly, gut microbiota are crucial in regulating the metabolic response to nutrient intake. As such, we aim to gain a mechanistic understanding of how nutrients and the intestinal microbiota may contribute to the metabolic health of the human host. By doing so, we hope to shed light on the pathogenesis of various common metabolic disorders including, but not limited to, obesity, type 2 diabetes, non-alcoholic liver disease, cardiometabolic diseases and malnutrition.

This Special Issue will focus on novel strategies and molecular mechanisms, as well as nutritional approaches to tackle obesity and its associated metabolic disturbances.

This Special Issue of the Biomolecules Journal, entitled “Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives”, aims to solicit original research papers or review articles on the current state of research in this field, including both discovery and preclinical studies.

We look forward to your contributions to this research field.

Dr. Marion Korach-André
Guest Editor

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