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Diseases, Volume 7, Issue 2

June 2019 - 14 articles

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Cover Story: Our case highlights the importance of considering HSV in the differential diagnosis of rectal masses, particularly in HIV-infected individuals with clinical manifestations and endoscopic findings consistent with proctitis. We also advocate the routine use of immunohistochemistry for viral pathogens as part of the diagnostic evaluation of rectal tumors. View this paper.

Articles (14)

  • Article
  • Open Access
41 Citations
8,085 Views
10 Pages

Preoperatory Anxiety in Patients Undergoing Cardiac Surgery

  • José Prado-Olivares and
  • Elena Chover-Sierra

Anxiety is a feeling of discomfort produced in face of an unknown event, as an impending cardiac surgery, that can lead to inconveniences in the intervention and subsequent recovery. Being the purpose of this research to analyze pre-surgical anxiety,...

  • Review
  • Open Access
35 Citations
7,360 Views
14 Pages

An increased interest regarding the impact of frailty on the prognosis of cardiovascular disease (CVD) has been observed in the last decade. Frailty is a syndrome characterized by a reduced biological reserve that increases the vulnerability of an in...

  • Article
  • Open Access
15 Citations
4,206 Views
15 Pages

Clinical Impact of the Increase in Immunosuppressive Cell-Related Gene Expression in Urine Sediment during Intravesical Bacillus Calmette-Guérin

  • Makito Miyake,
  • Shunta Hori,
  • Sayuri Ohnishi,
  • Takuya Owari,
  • Kota Iida,
  • Kenta Ohnishi,
  • Yosuke Morizawa,
  • Daisuke Gotoh,
  • Yoshitaka Itami and
  • Yasushi Nakai
  • + 7 authors

Background: The aim of this study is to evaluate the clinical impact of intravesical Bacillus Calmette-Guérin (BCG)-induced changes in blood/urinary immune markers. Methods: Time-course changes in blood/urinary clinical parameters and mRNA exp...

  • Communication
  • Open Access
2,947 Views
3 Pages

Epigenetics—Shedding Light on the Path Ahead for Material Sciences

  • Anne Krüger-Genge,
  • Olivia Mauger,
  • Joachim Storsberg and
  • Christian Schmidt

The harmonious regulation of bodily function is a necessity for healthy individuals. Looking from the viewpoint of material sciences, one can only marvel at the cellular factories, their renewal, and the overall control of messaging and control of re...

  • Communication
  • Open Access
44 Citations
6,553 Views
13 Pages

Stenotrophomonas maltophilia has been recognized as an emerging nosocomial pathogen in invasive infections of immunocompromised, severely debilitated patients with significant underlying illnesses. The first-choice drug in these infections is sulfame...

  • Article
  • Open Access
7 Citations
4,327 Views
16 Pages

Electrochemical Methodology for Evaluating Skin Oxidative Stress Status (SOSS)

  • Pincemail Joël,
  • Kaci Mouna-Messaouda,
  • Cheramy-Bien Jean-Paul,
  • Defraigne Jean-Olivier and
  • Meziane Smail

For the purpose of human disease prevention, several methods have been developed, and are still developing, to assess the oxidative stress status (OSS) of individuals. In the present paper, we describe an approach based on electrochemical detection a...

  • Case Report
  • Open Access
12 Citations
5,794 Views
8 Pages

Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis

  • Lourdes Roman-Malo,
  • Beatriz Bullon,
  • Manuel de Miguel and
  • Pedro Bullon

Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues. A father and a daughter of a family showing gingival hereditary fibromatosis w...

  • Case Report
  • Open Access
4 Citations
5,214 Views
4 Pages

A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan

  • Prashanth Rawla,
  • Jeffrey Pradeep Raj,
  • Sajid Melvin George,
  • Pavani Nathala and
  • Anantha R. Vellipuram

Rhabdomyolysis is caused by extensive damage to skeletal muscles resulting in elevated creatine phosphokinase (CPK), Lactate dehydrogenase (LDH), and aspartate aminotransferase (AST), leading to life-threatening consequences like acute renal failure,...

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