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Open AccessFeature PaperEditorial

Epigenetic Factors of Disease

1
Cell and Molecular Biology Program, Colorado State University, Fort Collins, CO 80523, USA
2
Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
3
Epidemiology Section, Colorado School of Public Health, Fort Collins, CO 80523, USA
4
Department of Ethnic Studies, Colorado State University, Fort Collins, CO 80523, USA
*
Author to whom correspondence should be addressed.
Diseases 2019, 7(2), 42; https://doi.org/10.3390/diseases7020042
Received: 8 June 2019 / Accepted: 10 June 2019 / Published: 14 June 2019
(This article belongs to the Special Issue Epigenetics and Disease)
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PDF [160 KB, uploaded 14 June 2019]

Abstract

The development of tissues involves the direction of specific programs for gene expression among distinct cell types. These programs are often established in a heritable state by virtue of epigenetic mechanisms and corresponding pathways of cellular memory. Thus, the broad synchronization in patterns of gene expression ultimately dictates cellular consequences. Aberrations in these epigenetic mechanisms are known to be associated with a range of diseases. Herein, we highlight epigenetic factors that, when aberrantly expressed, lead to a broad range of diseases. Further, we call upon the community of biomedical researchers to share their findings related to the epigenetic factors of disease. View Full-Text
Keywords: epigenetics; post-translational modifications; chromatin; nucleosome remodeling epigenetics; post-translational modifications; chromatin; nucleosome remodeling
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Alshiraihi, I.; Brown, M.A. Epigenetic Factors of Disease. Diseases 2019, 7, 42.

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