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A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan

1
Department of Internal Medicine/Hospitalist, SOVAH Health, Martinsville, VA 24112, USA
2
Department of Clinical Pharmacology, Seth G.S. Medical College & King Edward Memorial Hospital, Mumbai 400012, India
3
Department of Medicine/Nephrology, SOVAH Health, Martinsville, VA 24112, USA
4
Division of Infectious Diseases, University of Louisville, Louisville, KY 40202, USA
5
Department of Neurology, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
*
Author to whom correspondence should be addressed.
Diseases 2019, 7(2), 38; https://doi.org/10.3390/diseases7020038
Received: 17 April 2019 / Revised: 12 May 2019 / Accepted: 13 May 2019 / Published: 14 May 2019
Rhabdomyolysis is caused by extensive damage to skeletal muscles resulting in elevated creatine phosphokinase (CPK), Lactate dehydrogenase (LDH), and aspartate aminotransferase (AST), leading to life-threatening consequences like acute renal failure, cardiac arrhythmias, and hyperthermia. A variety of causes for muscle damage are known, and one of the most common is drug-induced. Statins and many other agents are known to induce muscle damage, but here we report Entresto™ (Sacubitril/Valsartan) induced rhabdomyolysis which has not been previously reported as solely responsible in the literature. View Full-Text
Keywords: rhabdomyolysis; entresto; sacubitril/valsartan; adverse drug reaction rhabdomyolysis; entresto; sacubitril/valsartan; adverse drug reaction
MDPI and ACS Style

Rawla, P.; Raj, J.P.; George, S.M.; Nathala, P.; Vellipuram, A.R. A Rare Adverse Event of Rhabdomyolysis Caused by Sacubitril/Valsartan. Diseases 2019, 7, 38.

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