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Diseases, Volume 10, Issue 1

March 2022 - 17 articles

Cover Story: In a person with a high level of Lp(a), the cholesterol in this particle has the potential to contribute a significant portion of the reported LDL-C. The concentration of Lp(a) in patients with potential FH is 40–60% higher than in those with unlikely FH. The results of our study show that the use of a corrected level of LDL-C based on Lp(a) concentration for FH clinical diagnosis leads to a significant diagnosis reclassification to less severe and reduces the likelihood of true FH. The LDL-C level corrected by Lp(a)-cholesterol should be considered when making the FH diagnosis in patients with Lp(a) concentration ≥40 mg/dl. The proportion of cholesterol in Lp(a) can reach 74% of total LDL-C concentration in patients with hyperlipoproteinemia(a). View this paper
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Articles (17)

  • Case Report
  • Open Access
9 Citations
4,446 Views
6 Pages

Human Rabies by Secondary Transmission in Argentina, 2021

  • Soledad Firpo,
  • María Guadalupe Piccirilli,
  • Rogelio Urizar,
  • Nicolas Vitta,
  • Stella Maris Hirmas Riade,
  • Constanza Leguizamón,
  • María Lorena Vico,
  • Gustavo Martínez,
  • Fernando J. Beltrán and
  • Daniel M. Cisterna

18 March 2022

Rabies is a zoonotic disease caused by the rabies virus (RABV) that causes fatal encephalitis in mammals. Bats can transmit the disease to urban canines and felines, which rarely infect humans, establishing a secondary link. The last case of human ra...

  • Article
  • Open Access
3 Citations
3,320 Views
13 Pages

Progression of Chronic Kidney Disease and All-Cause Mortality in Patients with Tricuspid Regurgitation

  • Fabian Schipmann,
  • Marwin Bannehr,
  • Valentin Hähnel,
  • Victoria Dworok,
  • Jonathan Nübel,
  • Christoph Edlinger,
  • Michael Lichtenauer,
  • Michael Haase,
  • Michael Zänker and
  • Christian Butter
  • + 1 author

16 March 2022

Aim: The impact of chronic kidney disease (CKD) on patient-related outcomes in patients with tricuspid regurgitation (TR) is well known. However, the impact of the progression of CKD in patients with TR and potentially modifiable risk factors of prog...

  • Article
  • Open Access
8 Citations
4,299 Views
11 Pages

Clinical Prediction of Type 2 Diabetes Mellitus (T2DM) via Anthropometric and Biochemical Variations in Prakriti

  • Shriti Singh,
  • Neeraj Kumar Agrawal,
  • Girish Singh,
  • Sangeeta Gehlot,
  • Santosh Kumar Singh and
  • Rajesh Singh

Type 2 Diabetes Mellitus (T2DM) is a complicated multifactorial illness involving hereditary and external environmental variables. The symptoms typically appear gradually over a number of years without realizing it. This viewpoint is further supporte...

  • Review
  • Open Access
4 Citations
4,108 Views
8 Pages

Inflammatory Bowel Disease: An Indication to Screen for Thrombophilia?

  • Nour M. Moukalled,
  • Jana G. Hashash and
  • Ali T. Taher

23 February 2022

Inflammatory bowel diseases (IBD) are systemic conditions characterized by multiple intestinal and extra-intestinal manifestations related to the associated chronic inflammatory state. Among their diverse extra-intestinal complications, venous thromb...

  • Case Report
  • Open Access
15 Citations
5,620 Views
6 Pages

Acute Demyelinating Encephalomyelitis Post-COVID-19 Vaccination: A Case Report and Literature Review

  • Khalid Al-Quliti,
  • Ahmad Qureshi,
  • Mohammed Quadri,
  • Babar Abdulhameed,
  • Alhanouf Alanazi and
  • Rakan Alhujeily

20 February 2022

New advancements in the medical community have rapidly occurred with the development of medical information across the globe during the COVID-19 pandemic. Several vaccine manufacturers were able to obtain clearance to administer vaccines in selected...

  • Review
  • Open Access
28 Citations
6,003 Views
14 Pages

Blood and Salivary Inflammatory Biomarkers Profile in Patients with Chronic Kidney Disease and Periodontal Disease: A Systematic Review

  • Lisandra Taísa Reginaldo Tavares,
  • Mariana Saavedra-Silva,
  • Joaquín Francisco López-Marcos,
  • Nélio Jorge Veiga,
  • Rogerio de Moraes Castilho and
  • Gustavo Vicentis de Oliveira Fernandes

17 February 2022

Introduction: Periodontitis is the most prevalent inflammatory disease worldwide. Its inflammatory levels spread systemically, which can be associated with chronic kidney disease. Biomarkers have the potential to diagnose and correlate periodontitis...

  • Review
  • Open Access
2 Citations
5,474 Views
14 Pages

Emerging Biomarkers for Diagnosis, Prevention and Treatment of Brain Metastases—From Biology to Clinical Utility

  • Priyakshi Kalita-de Croft,
  • Vaibhavi Joshi,
  • Jodi M. Saunus and
  • Sunil R. Lakhani

3 February 2022

Primary malignancies of the lung, skin (melanoma), and breast have higher propensity for metastatic spread to the brain. Advances in molecular tumour profiling have aided the development of targeted therapies, stereotactic radiotherapy, and immunothe...

  • Article
  • Open Access
7 Citations
3,876 Views
13 Pages

1 February 2022

Background: Hearing impairment (HI) is a major problem in Ghana; however, the few attempts at shedding light on its causes appear to overlook the adverse effects of some medications—a gap that this study sought to fill. Aminoglycoside therapy f...

  • Review
  • Open Access
21 Citations
8,702 Views
11 Pages

D-Amino Acids as a Biomarker in Schizophrenia

  • Kurumi Taniguchi,
  • Haruka Sawamura,
  • Yuka Ikeda,
  • Ai Tsuji,
  • Yasuko Kitagishi and
  • Satoru Matsuda

31 January 2022

D-amino acids may play key roles for specific physiological functions in different organs including the brain. Importantly, D-amino acids have been detected in several neurological disorders such as schizophrenia, amyotrophic lateral sclerosis, and a...

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Diseases - ISSN 2079-9721