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Antibiotics, Volume 14, Issue 1

January 2025 - 108 articles

Cover Story: Staphylococcus pseudintermedius is responsible for about 90% of skin infections and 20% to 94.3% of ear infections in dogs globally. Other coagulase-positive (CoPS) and -negative staphylococci (CoNS) have been isolated from canine pyoderma and otitis externa. Despite being considered less pathogenic, CoNS can act as reservoirs for antimicrobial resistance and virulence genes. Methicillin-resistant staphylococci present treatment challenges due to their resistance to beta-lactams and co-resistance to other antimicrobial drug classes. The aim of the present study was to investigate the molecular epidemiology of methicillin-resistant and -sensitive staphylococci cultured from clinical canine skin and ear infections in Queensland, Australia, using whole-genome sequencing to understand their genetic profiles. View this paper
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Articles (108)

  • Article
  • Open Access
1 Citations
1,655 Views
26 Pages

Background: The increasing prevalence of drug-resistant tuberculosis (TB) underscores the urgent need for novel antimicrobial agents. Methods: This study integrates cultivation optimization, nuclear magnetic resonance (NMR) fingerprinting, and princi...

  • Article
  • Open Access
3,033 Views
12 Pages

Management and Outcome of Invasive Clindamycin-Resistant MRSA Community-Associated Infections in Children

  • Amanda E. Macias,
  • Grant Stimes,
  • Sheldon L. Kaplan,
  • Jesus G. Vallejo,
  • Kristina G. Hulten and
  • J. Chase McNeil

Background: Clindamycin resistance among community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) complicates the management of a challenging infection. Little data exist to guide clinicians in the management of invasive clindamycin...

  • Article
  • Open Access
1 Citations
2,431 Views
24 Pages

Evaluation of Cinnamon Essential Oil and Its Emulsion on Biofilm-Associated Components of Acinetobacter baumannii Clinical Strains

  • Tea Ganić,
  • Ilinka Pećinar,
  • Biljana Nikolić,
  • Dušan Kekić,
  • Nina Tomić,
  • Stefana Cvetković,
  • Stefana Vuletić and
  • Dragana Mitić-Ćulafić

Background/Objectives: Acinetobacter baumannii, one of the most dangerous pathogens, is able to form biofilm structures and aggravate its treatment. For that reason, new antibiofilm agents are in need, and new sources of antibiofilm compounds are bei...

  • Article
  • Open Access
2 Citations
2,888 Views
13 Pages

Antibiotic Prescription Practice and Resistance Patterns of Bacterial Isolates from a Neonatal Intensive Care Unit: A Retrospective Study from Jordan

  • Mariam Alameri,
  • Lobna Gharaibeh,
  • Mervat Alsous,
  • Aseel Yaghi,
  • Asma’a Tanash,
  • Saqr Sa’id and
  • Hanan Sartawi

Background/Objectives: Neonatal sepsis is a systemic inflammation in neonates caused by bacteria, viruses, or fungi that can progress into severe conditions. In developing countries, neonatal sepsis is a major cause of mortality and a major public he...

  • Article
  • Open Access
2 Citations
2,869 Views
28 Pages

Background: Phage tail-like bacteriocins, or tailocins, provide a competitive advantage to producer cells by killing closely related bacteria. Morphologically similar to headless phages, their narrow target specificity is determined by receptor-bindi...

  • Article
  • Open Access
1 Citations
1,929 Views
20 Pages

Background: Antimicrobial resistance is one of the greatest challenges of our time, urging researchers in both veterinary and public health to engage in collaborative efforts, thereby fostering the One Health approach. Infections caused by Staphyloco...

  • Article
  • Open Access
3 Citations
3,188 Views
19 Pages

Background/Objectives: Given the magnitude and urgency of the global antimicrobial resistance (AMR) problem and the insufficiency of strategies to reduce antimicrobial use, there is a need for novel strategies. Traditional, Complementary, and Integra...

  • Article
  • Open Access
3 Citations
1,699 Views
20 Pages

Thromboelastometry-Based Profiling of Haemostatic Alterations in Neonatal Sepsis by Causative Pathogens

  • Rozeta Sokou,
  • Eleni A. Gounari,
  • Konstantina A. Tsante,
  • Aikaterini Konstantinidi,
  • Maria Lampridou,
  • Martha Theodoraki,
  • Anastasios G. Kriebardis,
  • Sotirios P. Fortis,
  • Nicoletta Iacovidou and
  • Andreas G. Tsantes

Background: Neonatal sepsis is a serious condition with high mortality, especially in premature and low-birth-weight neonates. This study aims to examine whether the haemostatic profile of neonates with sepsis defers depending on the type of bacteria...

  • Review
  • Open Access
1,809 Views
20 Pages

Oral Antibacterial Drug Prescribing in Primary Care Out-of-Hours Services: A Scoping Review

  • Sarah Khalid Al Hussain,
  • Rhian Deslandes,
  • Deborah Edwards and
  • Karen Louise Hodson

Background/Objectives: The rapid spread of antimicrobial resistance (AMR) presents a critical threat to global health. Primary care plays a significant role in this crisis, with oral antibacterial drugs among the most prescribed medications. Antibact...

  • Article
  • Open Access
2 Citations
3,528 Views
12 Pages

The rising threat of antimicrobial resistance (AMR) is a global concern in both human and veterinary medicine, with multidrug-resistant (MDR) pathogens such as Staphylococcus aureus and Staphylococcus pseudintermedius presenting significant challenge...

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Antibiotics - ISSN 2079-6382